RNA14_ASPOR
ID RNA14_ASPOR Reviewed; 1078 AA.
AC Q2UKV8;
DT 30-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT 24-JAN-2006, sequence version 1.
DT 25-MAY-2022, entry version 79.
DE RecName: Full=mRNA 3'-end-processing protein rna14;
GN Name=rna14; ORFNames=AO090003000655;
OS Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=510516;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 42149 / RIB 40;
RX PubMed=16372010; DOI=10.1038/nature04300;
RA Machida M., Asai K., Sano M., Tanaka T., Kumagai T., Terai G., Kusumoto K.,
RA Arima T., Akita O., Kashiwagi Y., Abe K., Gomi K., Horiuchi H.,
RA Kitamoto K., Kobayashi T., Takeuchi M., Denning D.W., Galagan J.E.,
RA Nierman W.C., Yu J., Archer D.B., Bennett J.W., Bhatnagar D.,
RA Cleveland T.E., Fedorova N.D., Gotoh O., Horikawa H., Hosoyama A.,
RA Ichinomiya M., Igarashi R., Iwashita K., Juvvadi P.R., Kato M., Kato Y.,
RA Kin T., Kokubun A., Maeda H., Maeyama N., Maruyama J., Nagasaki H.,
RA Nakajima T., Oda K., Okada K., Paulsen I., Sakamoto K., Sawano T.,
RA Takahashi M., Takase K., Terabayashi Y., Wortman J.R., Yamada O.,
RA Yamagata Y., Anazawa H., Hata Y., Koide Y., Komori T., Koyama Y.,
RA Minetoki T., Suharnan S., Tanaka A., Isono K., Kuhara S., Ogasawara N.,
RA Kikuchi H.;
RT "Genome sequencing and analysis of Aspergillus oryzae.";
RL Nature 438:1157-1161(2005).
CC -!- FUNCTION: Component of the cleavage factor IA (CFIA) complex, which is
CC involved in the endonucleolytic cleavage during polyadenylation-
CC dependent pre-mRNA 3'-end formation. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.
CC Note=Nucleus and/or cytoplasm. {ECO:0000250}.
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DR EMBL; AP007155; BAE57807.1; -; Genomic_DNA.
DR AlphaFoldDB; Q2UKV8; -.
DR SMR; Q2UKV8; -.
DR STRING; 510516.Q2UKV8; -.
DR EnsemblFungi; BAE57807; BAE57807; AO090003000655.
DR HOGENOM; CLU_007630_1_1_1; -.
DR OMA; WSVYLDY; -.
DR Proteomes; UP000006564; Chromosome 2.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0031124; P:mRNA 3'-end processing; IEA:InterPro.
DR InterPro; IPR003107; HAT.
DR InterPro; IPR045243; Rna14-like.
DR InterPro; IPR008847; Suf.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR19980; PTHR19980; 1.
DR Pfam; PF05843; Suf; 1.
DR SMART; SM00386; HAT; 5.
DR SUPFAM; SSF48452; SSF48452; 2.
PE 3: Inferred from homology;
KW Cytoplasm; mRNA processing; Nucleus; Reference proteome; Repeat.
FT CHAIN 1..1078
FT /note="mRNA 3'-end-processing protein rna14"
FT /id="PRO_0000238519"
FT REPEAT 280..312
FT /note="HAT 1"
FT REPEAT 314..345
FT /note="HAT 2"
FT REPEAT 356..391
FT /note="HAT 3"
FT REPEAT 405..438
FT /note="HAT 4"
FT REPEAT 475..508
FT /note="HAT 5"
FT REPEAT 520..552
FT /note="HAT 6"
FT REGION 15..209
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 222..251
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 632..663
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 851..950
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 36..65
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 66..80
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 81..117
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 152..172
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 186..209
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 222..240
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 856..890
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 896..917
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 918..949
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1078 AA; 120945 MW; 1CBD742DCEC2F391 CRC64;
MAEDDAEKAF FQAQAMNADS VDYKAVEDQG ASSDSDDYDP SKTLQDQYSA SILDSKQSEI
APSSASPSDP NPPTQSIPPE TDPSQPADSA YPSQTPSRAD SQASVSAPAS GTSVPLKTRT
IGGFVVEDED EDDAGDADYE PPAVLGVEDM NTISMNVPQQ PISGNANEDT PTPDVSMDGA
VQASADAKNF PNSSYTPASA AASKSDTPAL LSQDMYNSRT LQSENMQDSA AATPVPDSPS
TSKGRLPHDR VGILEDRIQE DPRGDIPAWL ELINEHRNRN RIDSAREVYE RFLTAFPFSA
EQWVAYATME SELNELYRLE QIFNRTLLTI PDVQLWTVYL DYVRRRNPLT TDTTGQSRRI
ISSAYDLALQ YVGVDKDSGS IWTDYVQFIR SGPGNVGGSG WQDQQKMDLL RKAYQKAICV
PTQAVNNLWK EYDQFEMGLN KLTGRKFLQE QSPAYMTARS SYTELQNITR DLNRTTLPRL
PPVLGSDGDI EFGQQVDIWK RWIKWEKGDP LVLKEEDQAA FKARVIYVYK QALMALRFLP
EIWFEAAEFC FLNDMENEGN EFLKNGIEAN PESCLLAFKR ADRLEITSES EQDPIKRGAK
VREPYDKLLN ALYDLIAKAR TRESQDVARL EETFAKINPD TQPSKTDDDD DDQSDSKARE
SMKNAQIEAL RNAHAIQIGI LSKTVSFAWI ALMRAMRRIQ GKGKPGEMPG SRQVFADARK
RGRITSDVYI ASALIEYHCY KDPAATKIFE RGAKLFPEDE NFALEYLKHL IDINDVINAR
AVFEMTVRKL ASNPENVHKT KPIFAFLHEY ESRYGDLVQV INLENRMREL FPEDPTLEQF
AHRYSSPAFD PTVVRPIISP SQTRPKTAFP TEQPVSRHGT PSSRYPDASV TNSPKRPLED
FDDEMNRPRK FIRADSPLKT TQRRQLDPPK RTQQVISNQT GSQFRSQGSP APLPRDIVYL
LSIIPSASAY NAGRFSPEKL VDLIRRIDMP TSISQIPLPP SVRGLGFPEM SICLWGRLPS
TTWPKTVHPC GKPTFIALSS ITRVKCKRFT GWRSPYIRKP SLPPYGTYSP SLAFLISV
