ID   RNA14_CANAL             Reviewed;         791 AA.
AC   Q5AM44; A0A1D8PGK2; Q5ALP5;
DT   30-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   10-MAY-2017, sequence version 2.
DT   03-AUG-2022, entry version 91.
DE   RecName: Full=mRNA 3'-end-processing protein RNA14;
GN   Name=RNA14; OrderedLocusNames=CAALFM_C202150CA;
GN   ORFNames=CaO19.1531, CaO19.9106;
OS   Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=237561;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA   Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA   Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA   Scherer S.;
RT   "The diploid genome sequence of Candida albicans.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=17419877; DOI=10.1186/gb-2007-8-4-r52;
RA   van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA   Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA   Chibana H., Nantel A., Magee P.T.;
RT   "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT   on the eight chromosomes.";
RL   Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=24025428; DOI=10.1186/gb-2013-14-9-r97;
RA   Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT   "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT   specific measurements and provides a simple model for repeat and indel
RT   structure.";
RL   Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
CC   -!- FUNCTION: Component of the cleavage factor IA (CFIA) complex, which is
CC       involved in the endonucleolytic cleavage during polyadenylation-
CC       dependent pre-mRNA 3'-end formation. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.
CC       Note=Nucleus and/or cytoplasm. {ECO:0000250}.
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DR   EMBL; CP017624; AOW27255.1; -; Genomic_DNA.
DR   RefSeq; XP_722575.2; XM_717482.2.
DR   AlphaFoldDB; Q5AM44; -.
DR   SMR; Q5AM44; -.
DR   STRING; 237561.Q5AM44; -.
DR   PRIDE; Q5AM44; -.
DR   GeneID; 3635749; -.
DR   KEGG; cal:CAALFM_C202150CA; -.
DR   CGD; CAL0000183478; orf19.9106.
DR   VEuPathDB; FungiDB:C2_02150C_A; -.
DR   eggNOG; KOG1914; Eukaryota.
DR   HOGENOM; CLU_007630_0_1_1; -.
DR   InParanoid; Q5AM44; -.
DR   OrthoDB; 331411at2759; -.
DR   PRO; PR:Q5AM44; -.
DR   Proteomes; UP000000559; Chromosome 2.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0032991; C:protein-containing complex; IEA:UniProt.
DR   GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR   GO; GO:0031124; P:mRNA 3'-end processing; IEA:InterPro.
DR   GO; GO:0031123; P:RNA 3'-end processing; IBA:GO_Central.
DR   InterPro; IPR003107; HAT.
DR   InterPro; IPR045243; Rna14-like.
DR   InterPro; IPR008847; Suf.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   PANTHER; PTHR19980; PTHR19980; 1.
DR   Pfam; PF05843; Suf; 1.
DR   SMART; SM00386; HAT; 7.
DR   SUPFAM; SSF48452; SSF48452; 2.
PE   3: Inferred from homology;
KW   Cytoplasm; mRNA processing; Nucleus; Reference proteome; Repeat.
FT   CHAIN           1..791
FT                   /note="mRNA 3'-end-processing protein RNA14"
FT                   /id="PRO_0000238520"
FT   REPEAT          44..76
FT                   /note="HAT 1"
FT   REPEAT          78..112
FT                   /note="HAT 2"
FT   REPEAT          119..154
FT                   /note="HAT 3"
FT   REPEAT          165..198
FT                   /note="HAT 4"
FT   REPEAT          231..263
FT                   /note="HAT 5"
FT   REPEAT          273..305
FT                   /note="HAT 6"
FT   REGION          379..449
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          725..745
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        386..408
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        412..449
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   791 AA;  91659 MW;  6539A8F66A583BCF CRC64;
     MFIPQNKSKR LSLDKIGQLE EDLELNPLDY NKWQKLIDQL IIKDNQEQVR NTFDKYLKIF
     KFDGASWCKY IKYELNRDEK EKVENLFQQC LGITDNVELC RLYVDYVRGV TDFVTGGEKA
     RGVVVQAFEF AINKVGIDIT SESLWQDYIQ FLQSWNPNAN WEQQQKIDLI RKVYKKFLTI
     PTENIEVSWS QYTKWENELN PATASKFISE KSGEFMLARS WNTEFNRITD KSLKRNLNPG
     DHNDEDVVKQ LKYWLRWLEL EKENKLELKD ETVNDKRIQY VYKQATYALP FVPEIWFQYV
     KYLLVQNEEG NLQESIRLLK EGGLVLNPKS MLLTFQLAEL YERDNSFNNA KIVFKNLLDA
     LQKDYNSVAN QIAELKERID PATDKDNIQE DDDDNEEEEE EENDNDNDND NGGDSKQQPP
     SKKLKLNPNG GQNGSNSENN GEAVSAPSSS VKLPQVYRIS LADSKQLLSF ENEQKRLSDA
     ITLTYVKFMI ASKRSEGIKE ARNVFKQARK FTDIGYQIFI ESALLEHYSD KKSTALKIFD
     LGKKNFATNG KFLLNYLDYL IMINDVDTMR TVIQSSDANF TKEIGNLQEE LKLTNLDPIT
     RKKLEKQITN LKKFLKQLYK KYISFAATFL SLDVTHSFAK KCEQLFPKDD PIDLFTDRYK
     LDNINIIKKD ELGRDDILTS FDGIIDEEEL QRLKRRKLSN GSGSSSSYSF NEEESKSAIK
     NIEEQKTRVQ QEQDQENQGI NKPEESFVGP SIIALMSALP NASYFGLPSE SVFNSEKLVT
     LFANLSNIPS Q