ID   RNA14_CANGA             Reviewed;         646 AA.
AC   Q6FU45;
DT   30-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 107.
DE   RecName: Full=mRNA 3'-end-processing protein RNA14;
GN   Name=RNA14; OrderedLocusNames=CAGL0F06479g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Component of the cleavage factor IA (CFIA) complex, which is
CC       involved in the endonucleolytic cleavage during polyadenylation-
CC       dependent pre-mRNA 3'-end formation. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.
CC       Note=Nucleus and/or cytoplasm. {ECO:0000250}.
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DR   EMBL; CR380952; CAG59173.1; -; Genomic_DNA.
DR   RefSeq; XP_446249.1; XM_446249.1.
DR   AlphaFoldDB; Q6FU45; -.
DR   SMR; Q6FU45; -.
DR   STRING; 5478.XP_446249.1; -.
DR   EnsemblFungi; CAG59173; CAG59173; CAGL0F06479g.
DR   GeneID; 2887866; -.
DR   KEGG; cgr:CAGL0F06479g; -.
DR   CGD; CAL0129762; CAGL0F06479g.
DR   VEuPathDB; FungiDB:CAGL0F06479g; -.
DR   eggNOG; KOG1914; Eukaryota.
DR   HOGENOM; CLU_007630_0_1_1; -.
DR   InParanoid; Q6FU45; -.
DR   OMA; PKRQYFK; -.
DR   Proteomes; UP000002428; Chromosome F.
DR   GO; GO:0005829; C:cytosol; IEA:EnsemblFungi.
DR   GO; GO:0005739; C:mitochondrion; IEA:EnsemblFungi.
DR   GO; GO:0005849; C:mRNA cleavage factor complex; IEA:EnsemblFungi.
DR   GO; GO:0003723; F:RNA binding; IEA:EnsemblFungi.
DR   GO; GO:0006378; P:mRNA polyadenylation; IEA:EnsemblFungi.
DR   GO; GO:0098789; P:pre-mRNA cleavage required for polyadenylation; IEA:EnsemblFungi.
DR   GO; GO:0072423; P:response to DNA damage checkpoint signaling; IEA:EnsemblFungi.
DR   InterPro; IPR003107; HAT.
DR   InterPro; IPR045243; Rna14-like.
DR   InterPro; IPR008847; Suf.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   PANTHER; PTHR19980; PTHR19980; 1.
DR   Pfam; PF05843; Suf; 1.
DR   SMART; SM00386; HAT; 6.
DR   SUPFAM; SSF48452; SSF48452; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; mRNA processing; Nucleus; Reference proteome; Repeat.
FT   CHAIN           1..646
FT                   /note="mRNA 3'-end-processing protein RNA14"
FT                   /id="PRO_0000238521"
FT   REPEAT          46..78
FT                   /note="HAT 1"
FT   REPEAT          80..114
FT                   /note="HAT 2"
FT   REPEAT          128..160
FT                   /note="HAT 3"
FT   REPEAT          171..204
FT                   /note="HAT 4"
FT   REPEAT          249..281
FT                   /note="HAT 5"
FT   REPEAT          290..322
FT                   /note="HAT 6"
FT   REGION          571..599
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        576..599
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   646 AA;  76307 MW;  056196438D2D2795 CRC64;
     MSTTNEETQA NASKDYSEDA LKMSYAAQPL DIMRALKLIE YYESKDDYDN SRKLYAELHE
     RFPLYSPLWT MHLQSELQRN EFDTVEKLLA QCLAGDLENN DLSLWSTYLD YVRRKNNLIT
     GGQEARAVVI KAFKLVMDKC ATFEPKASSF WNDYLGFLHQ WKPMNKWEEQ QRLDMIREVY
     KKMLCVPFDK LEKMWNQYTL WEQETNTLTA RKFIGELSAD YMKARSIYQE LLNVTANIRR
     TSPLNLRTAN KNNIPQYVLP CKKNDHTQLE AWLKWIAWEK ENKLELTEDA LKDRVTYVYK
     QAIQQLLFEP EIWYDYVMYE FDNDAARKNI LKVALQANPT SPTLTFKLAE CYEVENKSEE
     VQNCFEKTID ELLRQYKNDN GNDELSSDII WERKTLTYIY CIYMNTMKRL SGLSAARAVF
     GKCRKLKKAM THDIYVENAY LEFQNQNDHK TASKVLELGL KYFGDDGEYI NKYMDFLSLL
     NRGSQMKTLF ETSIEKVEDL RQLKKIYVKM IGYESKYGNL NNVYQLEKRF FEKFPDTDLI
     QLFSTRYKIQ DDNKIKNLEL TYKLPDIISS DGDPSGVDKS FKKRQIENDE NLPDSKRQKS
     QPLLPKEILD ILAVLPKKQY FKNAFLDPSN LVNYLNEQVK LADEEN