RNA14_EMENI
ID RNA14_EMENI Reviewed; 1075 AA.
AC Q5B3I8; C8V9S5;
DT 30-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT 19-OCT-2011, sequence version 2.
DT 03-AUG-2022, entry version 93.
DE RecName: Full=mRNA 3'-end-processing protein rna14;
GN Name=rna14; ORFNames=AN4892;
OS Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 /
OS M139) (Aspergillus nidulans).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Nidulantes.
OX NCBI_TaxID=227321;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX PubMed=16372000; DOI=10.1038/nature04341;
RA Galagan J.E., Calvo S.E., Cuomo C., Ma L.-J., Wortman J.R., Batzoglou S.,
RA Lee S.-I., Bastuerkmen M., Spevak C.C., Clutterbuck J., Kapitonov V.,
RA Jurka J., Scazzocchio C., Farman M.L., Butler J., Purcell S., Harris S.,
RA Braus G.H., Draht O., Busch S., D'Enfert C., Bouchier C., Goldman G.H.,
RA Bell-Pedersen D., Griffiths-Jones S., Doonan J.H., Yu J., Vienken K.,
RA Pain A., Freitag M., Selker E.U., Archer D.B., Penalva M.A., Oakley B.R.,
RA Momany M., Tanaka T., Kumagai T., Asai K., Machida M., Nierman W.C.,
RA Denning D.W., Caddick M.X., Hynes M., Paoletti M., Fischer R., Miller B.L.,
RA Dyer P.S., Sachs M.S., Osmani S.A., Birren B.W.;
RT "Sequencing of Aspergillus nidulans and comparative analysis with A.
RT fumigatus and A. oryzae.";
RL Nature 438:1105-1115(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX PubMed=19146970; DOI=10.1016/j.fgb.2008.12.003;
RA Wortman J.R., Gilsenan J.M., Joardar V., Deegan J., Clutterbuck J.,
RA Andersen M.R., Archer D., Bencina M., Braus G., Coutinho P., von Dohren H.,
RA Doonan J., Driessen A.J., Durek P., Espeso E., Fekete E., Flipphi M.,
RA Estrada C.G., Geysens S., Goldman G., de Groot P.W., Hansen K.,
RA Harris S.D., Heinekamp T., Helmstaedt K., Henrissat B., Hofmann G.,
RA Homan T., Horio T., Horiuchi H., James S., Jones M., Karaffa L.,
RA Karanyi Z., Kato M., Keller N., Kelly D.E., Kiel J.A., Kim J.M.,
RA van der Klei I.J., Klis F.M., Kovalchuk A., Krasevec N., Kubicek C.P.,
RA Liu B., Maccabe A., Meyer V., Mirabito P., Miskei M., Mos M., Mullins J.,
RA Nelson D.R., Nielsen J., Oakley B.R., Osmani S.A., Pakula T., Paszewski A.,
RA Paulsen I., Pilsyk S., Pocsi I., Punt P.J., Ram A.F., Ren Q., Robellet X.,
RA Robson G., Seiboth B., van Solingen P., Specht T., Sun J.,
RA Taheri-Talesh N., Takeshita N., Ussery D., vanKuyk P.A., Visser H.,
RA van de Vondervoort P.J., de Vries R.P., Walton J., Xiang X., Xiong Y.,
RA Zeng A.P., Brandt B.W., Cornell M.J., van den Hondel C.A., Visser J.,
RA Oliver S.G., Turner G.;
RT "The 2008 update of the Aspergillus nidulans genome annotation: a community
RT effort.";
RL Fungal Genet. Biol. 46:S2-13(2009).
CC -!- FUNCTION: Component of the cleavage factor IA (CFIA) complex, which is
CC involved in the endonucleolytic cleavage during polyadenylation-
CC dependent pre-mRNA 3'-end formation. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.
CC Note=Nucleus and/or cytoplasm. {ECO:0000250}.
CC -!- SEQUENCE CAUTION:
CC Sequence=EAA60970.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AACD01000084; EAA60970.1; ALT_SEQ; Genomic_DNA.
DR EMBL; BN001303; CBF76536.1; -; Genomic_DNA.
DR RefSeq; XP_662496.1; XM_657404.1.
DR AlphaFoldDB; Q5B3I8; -.
DR SMR; Q5B3I8; -.
DR STRING; 162425.CADANIAP00005510; -.
DR PRIDE; Q5B3I8; -.
DR EnsemblFungi; CBF76536; CBF76536; ANIA_04892.
DR EnsemblFungi; EAA60970; EAA60970; AN4892.2.
DR GeneID; 2872687; -.
DR KEGG; ani:AN4892.2; -.
DR eggNOG; KOG1914; Eukaryota.
DR HOGENOM; CLU_007630_1_1_1; -.
DR InParanoid; Q5B3I8; -.
DR OMA; WSVYLDY; -.
DR OrthoDB; 331411at2759; -.
DR Proteomes; UP000000560; Chromosome III.
DR Proteomes; UP000005890; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR GO; GO:0031124; P:mRNA 3'-end processing; IEA:InterPro.
DR GO; GO:0031123; P:RNA 3'-end processing; IBA:GO_Central.
DR InterPro; IPR003107; HAT.
DR InterPro; IPR045243; Rna14-like.
DR InterPro; IPR008847; Suf.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR19980; PTHR19980; 1.
DR Pfam; PF05843; Suf; 1.
DR SMART; SM00386; HAT; 6.
DR SUPFAM; SSF48452; SSF48452; 2.
PE 3: Inferred from homology;
KW Cytoplasm; mRNA processing; Nucleus; Reference proteome; Repeat.
FT CHAIN 1..1075
FT /note="mRNA 3'-end-processing protein rna14"
FT /id="PRO_0000238524"
FT REPEAT 270..302
FT /note="HAT 1"
FT REPEAT 304..335
FT /note="HAT 2"
FT REPEAT 346..381
FT /note="HAT 3"
FT REPEAT 395..428
FT /note="HAT 4"
FT REPEAT 465..498
FT /note="HAT 5"
FT REPEAT 510..542
FT /note="HAT 6"
FT REGION 20..185
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 215..237
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 621..653
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 840..941
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 23..73
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 88..111
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 150..185
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 841..858
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 865..879
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 885..903
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 905..940
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1075 AA; 120475 MW; DC3053CB5502F956 CRC64;
MAEDDAEKAF FEAQAMNAGS MGYNGAEDQN ANASDSDEYD PSSTLQDQYP APSENLQLQE
TDTPTSVSQP QPSFREDADP AGNAHPSQPP SRPESQASTS VPATGVSVQP KTRTIGGFVV
EDEDEDDAGD ADYEPPAVLG VEDMNIIPSQ PIPGNANEAT STPDVSLDEA AQESASAKNV
PNSSLSSVSL AFKNDGSMDL GQNLYNSRTS LQPEIARESA TATPAPDSPS TAKGRLPHDR
VGILEDRIRE DPRGDIPAWL ELINEHRSRN RIDSARDVYE RFLKVFPLSA EMWVAYATME
SELNELFRLE QIFNRTLLTI PAVQLWTVYL DYVRRRNPLS TDTTGQARKV ISSAYELALQ
HIGMDKESGS IWADYIQFIR SGPGNVGGSG WQDQQKMDLL RKAYQRAICV PMQAVNTLWK
EYDQFEMGLN KLTGRKFLQE QSPSYMTARS SYTELQNFTR DLNRTTLPRL PPVPGSEGDF
EYLQQIEIWK RWINWEKGDP LVLKEDDLTA YKGRVVYVYK QALMALRFLP EIWFEAADFC
FLNDMETEGN EFLKNGIDAN PESCLLAFKR ADRLEITSES EQDPIKRGAK VREPYDRLLD
ALYDLIAKAR TREAQDVARL EETFKLRPDT QPAANDDDDD DQSETKAKES VKNAQIEAVR
HAHSIQIGIL SKTVSFAWIA LMRAMRRIQG KGKPGEVPGS RQVFADARKR GRITSDVYIA
SALIEYHCYK DPAATKIFER GAKLFPEDEN FALEYLKHLI DINDIINARA VFEMTVRKLA
ANPENVHKTK PIFAFLHEYE SRYGDLVQVI NLETRMRELF PDDPTLEQFA HRFSAPNFDP
TTFRPIISPS QTRPKTVYPG GQVPSRHGTP SSRFPEASVT NSPKRPLEDF DDDMSRPRKF
VRGESPLRTT TQRRQLDQQK RTQTALQVPS SGSQYRSQGS PAPLPRDIVY LLSVIPPAST
YTAGRFSAEK MIDLVRRLDL PASISQIPLP QSARGLGTGQ TTIGGQQFSD DGGYYYKGGV
VDMCALHFMD DGVFRLYVAG LAGNILARIL FFGSGGLLAY LLRTVQIWDP EIPRR
