RNA14_GIBZE
ID RNA14_GIBZE Reviewed; 997 AA.
AC Q4IR09; A0A098D1E1; A0A0E0RLZ0; V6QTG7;
DT 30-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT 16-AUG-2005, sequence version 1.
DT 25-MAY-2022, entry version 91.
DE RecName: Full=mRNA 3'-end-processing protein RNA14;
GN Name=RNA14; ORFNames=FGRRES_00349, FGSG_00349;
OS Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084
OS / PH-1) (Wheat head blight fungus) (Fusarium graminearum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium.
OX NCBI_TaxID=229533;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1;
RX PubMed=17823352; DOI=10.1126/science.1143708;
RA Cuomo C.A., Gueldener U., Xu J.-R., Trail F., Turgeon B.G., Di Pietro A.,
RA Walton J.D., Ma L.-J., Baker S.E., Rep M., Adam G., Antoniw J., Baldwin T.,
RA Calvo S.E., Chang Y.-L., DeCaprio D., Gale L.R., Gnerre S., Goswami R.S.,
RA Hammond-Kosack K., Harris L.J., Hilburn K., Kennell J.C., Kroken S.,
RA Magnuson J.K., Mannhaupt G., Mauceli E.W., Mewes H.-W., Mitterbauer R.,
RA Muehlbauer G., Muensterkoetter M., Nelson D., O'Donnell K., Ouellet T.,
RA Qi W., Quesneville H., Roncero M.I.G., Seong K.-Y., Tetko I.V., Urban M.,
RA Waalwijk C., Ward T.J., Yao J., Birren B.W., Kistler H.C.;
RT "The Fusarium graminearum genome reveals a link between localized
RT polymorphism and pathogen specialization.";
RL Science 317:1400-1402(2007).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1;
RX PubMed=20237561; DOI=10.1038/nature08850;
RA Ma L.-J., van der Does H.C., Borkovich K.A., Coleman J.J., Daboussi M.-J.,
RA Di Pietro A., Dufresne M., Freitag M., Grabherr M., Henrissat B.,
RA Houterman P.M., Kang S., Shim W.-B., Woloshuk C., Xie X., Xu J.-R.,
RA Antoniw J., Baker S.E., Bluhm B.H., Breakspear A., Brown D.W.,
RA Butchko R.A.E., Chapman S., Coulson R., Coutinho P.M., Danchin E.G.J.,
RA Diener A., Gale L.R., Gardiner D.M., Goff S., Hammond-Kosack K.E.,
RA Hilburn K., Hua-Van A., Jonkers W., Kazan K., Kodira C.D., Koehrsen M.,
RA Kumar L., Lee Y.-H., Li L., Manners J.M., Miranda-Saavedra D.,
RA Mukherjee M., Park G., Park J., Park S.-Y., Proctor R.H., Regev A.,
RA Ruiz-Roldan M.C., Sain D., Sakthikumar S., Sykes S., Schwartz D.C.,
RA Turgeon B.G., Wapinski I., Yoder O., Young S., Zeng Q., Zhou S.,
RA Galagan J., Cuomo C.A., Kistler H.C., Rep M.;
RT "Comparative genomics reveals mobile pathogenicity chromosomes in
RT Fusarium.";
RL Nature 464:367-373(2010).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1;
RX PubMed=26198851; DOI=10.1186/s12864-015-1756-1;
RA King R., Urban M., Hammond-Kosack M.C.U., Hassani-Pak K.,
RA Hammond-Kosack K.E.;
RT "The completed genome sequence of the pathogenic ascomycete fungus Fusarium
RT graminearum.";
RL BMC Genomics 16:544-544(2015).
CC -!- FUNCTION: Component of the cleavage factor IA (CFIA) complex, which is
CC involved in the endonucleolytic cleavage during polyadenylation-
CC dependent pre-mRNA 3'-end formation. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.
CC Note=Nucleus and/or cytoplasm. {ECO:0000250}.
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DR EMBL; DS231663; ESU05521.1; -; Genomic_DNA.
DR EMBL; HG970332; CEF72265.1; -; Genomic_DNA.
DR RefSeq; XP_011316006.1; XM_011317704.1.
DR AlphaFoldDB; Q4IR09; -.
DR SMR; Q4IR09; -.
DR STRING; 5518.FGSG_00349P0; -.
DR EnsemblFungi; ESU05521; ESU05521; FGSG_00349.
DR GeneID; 23547840; -.
DR KEGG; fgr:FGSG_00349; -.
DR VEuPathDB; FungiDB:FGRAMPH1_01G00925; -.
DR eggNOG; KOG1914; Eukaryota.
DR HOGENOM; CLU_007630_1_1_1; -.
DR InParanoid; Q4IR09; -.
DR Proteomes; UP000070720; Chromosome 1.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0031124; P:mRNA 3'-end processing; IEA:InterPro.
DR InterPro; IPR003107; HAT.
DR InterPro; IPR045243; Rna14-like.
DR InterPro; IPR008847; Suf.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR19980; PTHR19980; 1.
DR Pfam; PF05843; Suf; 1.
DR SMART; SM00386; HAT; 6.
DR SUPFAM; SSF48452; SSF48452; 2.
PE 3: Inferred from homology;
KW Cytoplasm; mRNA processing; Nucleus; Reference proteome; Repeat.
FT CHAIN 1..997
FT /note="mRNA 3'-end-processing protein RNA14"
FT /id="PRO_0000238525"
FT REPEAT 194..226
FT /note="HAT 1"
FT REPEAT 228..259
FT /note="HAT 2"
FT REPEAT 270..305
FT /note="HAT 3"
FT REPEAT 319..352
FT /note="HAT 4"
FT REPEAT 389..422
FT /note="HAT 5"
FT REPEAT 434..466
FT /note="HAT 6"
FT REPEAT 654..686
FT /note="HAT 7"
FT REGION 1..152
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 549..579
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 792..854
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 907..997
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 69..83
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 91..113
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 116..138
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 792..815
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 997 AA; 112359 MW; B985E7BC0573C934 CRC64;
MASEGTSWGA EDIGAQGDQV QHSEEQVDNY AHDSLASGDA DAADNGTEDD GGEYDPESVT
IGTPAMVPEP ASSGTQRQTS KPKMSGGFIV EASDDEDEDE DEDEDEDEDE QPASAVPQTD
AVSTQNHPGP STTSDEHVPA APTHAPVPPA VPSNVTPVLP GFGPVDLLEF RVKEDPRGDM
DAWQELIASH RDFSPLEKAR STYNRFVEIF PQAADKWVEW IELELKYNNF VEVEQLFGRC
LMQVPNVKLW TVYLDYIRRR NDLNNDPSGQ ARRTVTQSYE FVIDNIGVDR DSGNIWQQYV
QFVKNGPGQI DGTDWQDRQK MDQLRGIYRR AVAVPMSTVN NLWKEYDQFE MGLNKMTGRK
FIQERSPVYM SAKSANIALD NITRHLDRTN LPRLPPAPGF NGDQEFRDQV EMWKKWIAWE
KEDPLVLKSD EPKAYNQRVL HVYKQALMAL RFWPEIWVDA AEWCFQNDIR ENDKEMGTEL
LVEGIKANRE SVLLALKHAD HIEVNYPDKE VDKAEFAQAV RKPYDDVLET LYEMGDKVKE
REKLEISTLK QAAAQDPVQT SIEENDDDED NTPKRSPTEE RILAIQKGYA AETQLLSRTI
SYVWIALARA MRRIQGKGSQ AEGGLRKVFT DARQKGRLTS DVYVAVALLE SVVYKDPVGA
KIFERGARLF PNDEMFMIEY LKYLHSKDDT TNARVVFETC INRLVSNPDT LAKAKLLYAY
FHKYESQYGE LSQISKLEDR MAELFPEDPK LKSFVDRFST EKFDPIATPI IISKTAQMRP
KQIVPVVQHQ HQQSISLRNS PMPVRQEQNP RPQYVRATAS PKRPLAVDDE ELNPPKRLAR
GASPLKGAAG RRLDQQRRNQ ASALHRDITF LLNILPSSQS YDAQRFNSAA LVSILRDTEI
PDFATLKAAG GGQPRFGNPT HTRQPSGEFV NRPLSPYGRM SAAAGGYRNS PLRPETGNAY
QSNPYPPPEA SGQQPTWPQA PGGYGAPAPG QFGGYRY
