ID   RNA14_YARLI             Reviewed;         806 AA.
AC   Q6C8L8;
DT   30-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 92.
DE   RecName: Full=mRNA 3'-end-processing protein RNA14;
GN   Name=RNA14; OrderedLocusNames=YALI0D18612g;
OS   Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Dipodascaceae; Yarrowia.
OX   NCBI_TaxID=284591;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CLIB 122 / E 150;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Component of the cleavage factor IA (CFIA) complex, which is
CC       involved in the endonucleolytic cleavage during polyadenylation-
CC       dependent pre-mRNA 3'-end formation. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.
CC       Note=Nucleus and/or cytoplasm. {ECO:0000250}.
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DR   EMBL; CR382130; CAG81186.1; -; Genomic_DNA.
DR   RefSeq; XP_502994.1; XM_502994.1.
DR   AlphaFoldDB; Q6C8L8; -.
DR   SMR; Q6C8L8; -.
DR   STRING; 4952.CAG81186; -.
DR   EnsemblFungi; CAG81186; CAG81186; YALI0_D18612g.
DR   GeneID; 2911125; -.
DR   KEGG; yli:YALI0D18612g; -.
DR   VEuPathDB; FungiDB:YALI0_D18612g; -.
DR   HOGENOM; CLU_007630_0_1_1; -.
DR   InParanoid; Q6C8L8; -.
DR   OMA; PKRQYFK; -.
DR   Proteomes; UP000001300; Chromosome D.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0032991; C:protein-containing complex; IEA:UniProt.
DR   GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR   GO; GO:0031124; P:mRNA 3'-end processing; IEA:InterPro.
DR   GO; GO:0031123; P:RNA 3'-end processing; IBA:GO_Central.
DR   InterPro; IPR003107; HAT.
DR   InterPro; IPR045243; Rna14-like.
DR   InterPro; IPR008847; Suf.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   PANTHER; PTHR19980; PTHR19980; 1.
DR   Pfam; PF05843; Suf; 1.
DR   SMART; SM00386; HAT; 7.
DR   SUPFAM; SSF48452; SSF48452; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; mRNA processing; Nucleus; Reference proteome; Repeat.
FT   CHAIN           1..806
FT                   /note="mRNA 3'-end-processing protein RNA14"
FT                   /id="PRO_0000238530"
FT   REPEAT          221..253
FT                   /note="HAT 1"
FT   REPEAT          255..286
FT                   /note="HAT 2"
FT   REPEAT          299..334
FT                   /note="HAT 3"
FT   REPEAT          345..378
FT                   /note="HAT 4"
FT   REPEAT          404..440
FT                   /note="HAT 5"
FT   REGION          1..187
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          729..770
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        62..110
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        147..183
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        729..756
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   806 AA;  90675 MW;  40FB5EC354832048 CRC64;
     MSDDYDPTAV AFKPGDMETD MNTGEPLALE AEAAAKDPAH NEESGEDTNA NVESGTLVHQ
     GDEPESIDKE DKVEDGPDTK SDGGVLDEPK DGEQRDDEKK EEHKPENPSE EVAEDDDYVP
     AAVSEPVEED SAGGGSVGGT GIPDGAISSL AASTTIPPPS DPNQVGGGAS STSNNNNSGP
     DNNKRKRLAT DTIGILEDRI AANPRDMPAW LDLISTIVRK EKLDESRDIY ERFLALYPLS
     AEIWIEYITL EMDNGEFKRL EQLFGRCLTR LPNLKLWNIY LTYVRRVNVL SSESDKITEA
     RTNIIKAFEF YLDHVGIDRE SGNVWFEYLD FIKSKPATTT WEEQQKNDLT RKIYRKAIGI
     PLNNLSILWT AYTNFEYSLN KATARKFINE KSGSCQNARQ CQTVLENLMR GLDRSSVPKS
     GPRDEFQVRA WKKWIDWEKS NPLGTDNKAE TNKRLLYCLK QAVMSLQFVP EIWFLAAEYC
     FDDPLLKTEA LQFLKDGLSL NPNSSLLAFR LAEYYEREAD AEKMRTIYDE HIESLGKERQ
     ALIEAQGDPE AEPTAEIIKL NTQISIAYSV CMKAVKRFEG IKPGRMVFKK ARNTGFATYH
     IYVASALMEF HHNKNPTVAT NVFELGLKYC GSNAAYVQHY LDFLISLHDD TNARALFEKT
     IPLLGPSDAA SLIKSMIKFE SDFGEITSVV KLQDRLRQLN PDTSPITIIA DRFATSDFDV
     IRQCDMLQKP KSRTDEDSDS ERPSKRARRT SHGNDQGDKM EPFNLPQKID ALLRQLPNSS
     DYGEATFDPQ RLVDLFRDVR IPDGLL