RNFA_VIBC3
ID RNFA_VIBC3 Reviewed; 213 AA.
AC A0A0H3AKU6;
DT 28-MAR-2018, integrated into UniProtKB/Swiss-Prot.
DT 16-SEP-2015, sequence version 1.
DT 25-MAY-2022, entry version 24.
DE RecName: Full=Ion-translocating oxidoreductase complex subunit A {ECO:0000255|HAMAP-Rule:MF_00459, ECO:0000305};
DE EC=7.-.-.- {ECO:0000255|HAMAP-Rule:MF_00459, ECO:0000305};
DE AltName: Full=Rnf electron transport complex subunit A {ECO:0000255|HAMAP-Rule:MF_00459, ECO:0000305};
GN Name=rnfA {ECO:0000255|HAMAP-Rule:MF_00459};
GN OrderedLocusNames=VC0395_A0538 {ECO:0000312|EMBL:ABQ21142.1};
OS Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 /
OS O395).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=345073;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 39541 / Classical Ogawa 395 / O395;
RA Heidelberg J.;
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP SUBCELLULAR LOCATION, AND TOPOLOGY.
RC STRAIN=ATCC 39541 / Classical Ogawa 395 / O395;
RX PubMed=25831459; DOI=10.1021/acs.biochem.5b00020;
RA Hreha T.N., Mezic K.G., Herce H.D., Duffy E.B., Bourges A., Pryshchep S.,
RA Juarez O., Barquera B.;
RT "Complete topology of the RNF complex from Vibrio cholerae.";
RL Biochemistry 54:2443-2455(2015).
CC -!- FUNCTION: Part of a membrane-bound complex that couples electron
CC transfer with translocation of ions across the membrane.
CC {ECO:0000255|HAMAP-Rule:MF_00459}.
CC -!- SUBUNIT: The complex is composed of six subunits: RnfA, RnfB, RnfC,
CC RnfD, RnfE and RnfG. {ECO:0000255|HAMAP-Rule:MF_00459}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_00459, ECO:0000269|PubMed:25831459}; Multi-pass membrane
CC protein {ECO:0000255|HAMAP-Rule:MF_00459}.
CC -!- SIMILARITY: Belongs to the NqrDE/RnfAE family. {ECO:0000255|HAMAP-
CC Rule:MF_00459}.
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DR EMBL; CP000627; ABQ21142.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0H3AKU6; -.
DR SMR; A0A0H3AKU6; -.
DR STRING; 345073.VC395_1032; -.
DR EnsemblBacteria; ABQ21142; ABQ21142; VC0395_A0538.
DR KEGG; vco:VC0395_A0538; -.
DR PATRIC; fig|345073.21.peg.1002; -.
DR eggNOG; COG4657; Bacteria.
DR OMA; CPFFGVS; -.
DR Proteomes; UP000000249; Chromosome 2.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022900; P:electron transport chain; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00459; RsxA_RnfA; 1.
DR InterPro; IPR011293; Ion_transpt_RnfA/RsxA.
DR InterPro; IPR003667; NqrDE/RnfAE.
DR Pfam; PF02508; Rnf-Nqr; 1.
DR PIRSF; PIRSF006102; NQR_DE; 1.
DR TIGRFAMs; TIGR01943; rnfA; 1.
PE 1: Evidence at protein level;
KW Cell inner membrane; Cell membrane; Electron transport; Membrane;
KW Translocase; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..213
FT /note="Ion-translocating oxidoreductase complex subunit A"
FT /id="PRO_0000443484"
FT TOPO_DOM 1..24
FT /note="Periplasmic"
FT /evidence="ECO:0000305|PubMed:25831459"
FT TRANSMEM 25..45
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00459"
FT TOPO_DOM 46..58
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305|PubMed:25831459"
FT TRANSMEM 59..79
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00459"
FT TOPO_DOM 80..86
FT /note="Periplasmic"
FT /evidence="ECO:0000305|PubMed:25831459"
FT TRANSMEM 87..107
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00459"
FT TOPO_DOM 108..121
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305|PubMed:25831459"
FT TRANSMEM 122..142
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00459"
FT TOPO_DOM 143..153
FT /note="Periplasmic"
FT /evidence="ECO:0000305|PubMed:25831459"
FT TRANSMEM 154..174
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00459"
FT TOPO_DOM 175..190
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305|PubMed:25831459"
FT TRANSMEM 191..211
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00459"
FT TOPO_DOM 212..213
FT /note="Periplasmic"
FT /evidence="ECO:0000269|PubMed:25831459"
SQ SEQUENCE 213 AA; 23263 MW; A1129A2106DD00BC CRC64;
MLLLWQSRIM PGSEANIYIT MTEYLLLLIG TVLVNNFVLV KFLGLCPFMG VSKKLETAIG
MGLATTFVLT LASVCAYLVE SYVLRPLGIE YLRTMSFILV IAVVVQFTEM VVHKTSPTLY
RLLGIFLPLI TTNCAVLGVA LLNINENHNF IQSIIYGFGA AVGFSLVLIL FASMRERIHV
ADVPAPFKGA SIAMITAGLM SLAFMGFTGL VKL
