RNFC_RHOCB
ID RNFC_RHOCB Reviewed; 519 AA.
AC D5ARZ1;
DT 28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT 15-JUN-2010, sequence version 1.
DT 03-AUG-2022, entry version 68.
DE RecName: Full=Ion-translocating oxidoreductase complex subunit C {ECO:0000255|HAMAP-Rule:MF_00461, ECO:0000305};
DE EC=7.-.-.- {ECO:0000255|HAMAP-Rule:MF_00461, ECO:0000305};
DE AltName: Full=Nitrogen fixation protein RnfC {ECO:0000305};
DE AltName: Full=Rnf electron transport complex subunit C {ECO:0000255|HAMAP-Rule:MF_00461, ECO:0000305};
GN Name=rnfC {ECO:0000255|HAMAP-Rule:MF_00461, ECO:0000303|PubMed:9154934};
GN OrderedLocusNames=RCAP_rcc03289;
OS Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC Rhodobacteraceae; Rhodobacter.
OX NCBI_TaxID=272942;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-309 / NBRC 16581 / SB1003;
RX PubMed=20418398; DOI=10.1128/jb.00366-10;
RA Strnad H., Lapidus A., Paces J., Ulbrich P., Vlcek C., Paces V.,
RA Haselkorn R.;
RT "Complete genome sequence of the photosynthetic purple nonsulfur bacterium
RT Rhodobacter capsulatus SB 1003.";
RL J. Bacteriol. 192:3545-3546(2010).
RN [2]
RP FUNCTION, AND SUBCELLULAR LOCATION.
RC STRAIN=ATCC BAA-309 / NBRC 16581 / SB1003;
RX PubMed=9154934; DOI=10.1021/bi970014q;
RA Kumagai H., Fujiwara T., Matsubara H., Saeki K.;
RT "Membrane localization, topology, and mutual stabilization of the rnfABC
RT gene products in Rhodobacter capsulatus and implications for a new family
RT of energy-coupling NADH oxidoreductases.";
RL Biochemistry 36:5509-5521(1997).
CC -!- FUNCTION: Part of a membrane-bound complex that couples electron
CC transfer with translocation of ions across the membrane (By
CC similarity). Required for nitrogen fixation. Stabilizes RnfB
CC (PubMed:9154934). {ECO:0000255|HAMAP-Rule:MF_00461,
CC ECO:0000269|PubMed:9154934}.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00461};
CC Note=Binds 2 [4Fe-4S] clusters per subunit. {ECO:0000255|HAMAP-
CC Rule:MF_00461};
CC -!- SUBUNIT: The complex is composed of six subunits: RnfA, RnfB, RnfC,
CC RnfD, RnfE and RnfG. {ECO:0000255|HAMAP-Rule:MF_00461}.
CC -!- SUBCELLULAR LOCATION: Cellular chromatophore membrane
CC {ECO:0000255|HAMAP-Rule:MF_00461, ECO:0000269|PubMed:9154934};
CC Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_00461,
CC ECO:0000269|PubMed:9154934}.
CC -!- SIMILARITY: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC
CC subfamily. {ECO:0000255|HAMAP-Rule:MF_00461}.
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DR EMBL; CP001312; ADE87013.1; -; Genomic_DNA.
DR RefSeq; WP_013068985.1; NC_014034.1.
DR AlphaFoldDB; D5ARZ1; -.
DR SMR; D5ARZ1; -.
DR STRING; 272942.RCAP_rcc03289; -.
DR PRIDE; D5ARZ1; -.
DR EnsemblBacteria; ADE87013; ADE87013; RCAP_rcc03289.
DR GeneID; 31492069; -.
DR KEGG; rcp:RCAP_rcc03289; -.
DR eggNOG; COG4656; Bacteria.
DR HOGENOM; CLU_010808_6_2_5; -.
DR OMA; YPMGSEK; -.
DR OrthoDB; 688908at2; -.
DR Proteomes; UP000002361; Chromosome.
DR GO; GO:0042717; C:plasma membrane-derived chromatophore membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0009055; F:electron transfer activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0009399; P:nitrogen fixation; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.50.11540; -; 1.
DR HAMAP; MF_00461; RsxC_RnfC; 1.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR010208; Ion_transpt_RnfC/RsxC.
DR InterPro; IPR011538; Nuo51_FMN-bd.
DR InterPro; IPR037225; Nuo51_FMN-bd_sf.
DR InterPro; IPR026902; RnfC_N.
DR InterPro; IPR019554; Soluble_ligand-bd.
DR PANTHER; PTHR43034; PTHR43034; 1.
DR Pfam; PF01512; Complex1_51K; 1.
DR Pfam; PF13237; Fer4_10; 1.
DR Pfam; PF13375; RnfC_N; 1.
DR Pfam; PF10531; SLBB; 1.
DR SUPFAM; SSF142019; SSF142019; 1.
DR TIGRFAMs; TIGR01945; rnfC; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 2.
DR PROSITE; PS51379; 4FE4S_FER_2; 2.
PE 3: Inferred from homology;
KW 4Fe-4S; Electron transport; Iron; Iron-sulfur; Membrane; Metal-binding;
KW Nitrogen fixation; Reference proteome; Repeat; Translocase; Transport.
FT CHAIN 1..519
FT /note="Ion-translocating oxidoreductase complex subunit C"
FT /id="PRO_0000410721"
FT DOMAIN 372..401
FT /note="4Fe-4S ferredoxin-type 1"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00461"
FT DOMAIN 411..440
FT /note="4Fe-4S ferredoxin-type 2"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00461"
FT REGION 494..519
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 381
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00461"
FT BINDING 384
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00461"
FT BINDING 387
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00461"
FT BINDING 391
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00461"
FT BINDING 420
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00461"
FT BINDING 423
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00461"
FT BINDING 426
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00461"
FT BINDING 430
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00461"
SQ SEQUENCE 519 AA; 55588 MW; E5451EB2A3FA6026 CRC64;
MRLPSIATLF HPLQSFSIRG GIHPETHKHL TSECEIETMP MPALIRLPLQ QHIGAEAEPI
VKRDDLVLKG QLIAKARGPL SANIHAPTSG RVIAVGHFVA PHASGLPVPT ITIRPDGEDK
WGPHLPRLRP ENAAPEEIAA QVAAAGIVGM GGATFPSAVK LNLRAKYDLT TLIINGAECE
PYLTCDDRLM RERAEEIADG IGIMARALGV KQVFVAIESN KPQAIEAMTR YNRALGYTFK
IHVVPTQYPM GSEKHLVKMI TGQETPARAL TADLGVVVHN IATAHAVHLA VRYGEPLIAR
TVTVSGHGIR RPANLRVLIG TPVSEIIAHC GGFTEEPDRL LLGGPMMGMP IQNPRVPVVK
GTNGILALTA AETPEAKTMP CIRCGRCVQG CPVGLTPFEL NARIHAGDLE GAAKVGLMDC
LACGCCSYNC PANLPLVQSF QFAKGKLSER QSRKHQQEET KRLAAARKAR EEAIAEAKKQ
MMLKRKAEMA AKKKAEEAAA AAAMPPPATA TAIQGEATP
