AB1E_ARATH
ID AB1E_ARATH Reviewed; 603 AA.
AC Q9LID6;
DT 07-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 134.
DE RecName: Full=ABC transporter E family member 1;
DE Short=ABC transporter ABCE.1;
DE Short=AtABCE1;
DE AltName: Full=RNase L inhibitor-like protein 1;
DE Short=AtRLI1;
DE Short=AthaRLI1;
GN Name=ABCE1; Synonyms=RLI1; OrderedLocusNames=At3g13640; ORFNames=MMM17.7;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10907853; DOI=10.1093/dnares/7.3.217;
RA Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence
RT features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC
RT clones.";
RL DNA Res. 7:217-221(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=11346655; DOI=10.1074/jbc.m103104200;
RA Sanchez-Fernandez R., Davies T.G., Coleman J.O., Rea P.A.;
RT "The Arabidopsis thaliana ABC protein superfamily, a complete inventory.";
RL J. Biol. Chem. 276:30231-30244(2001).
RN [5]
RP GENE FAMILY.
RX PubMed=11855639; DOI=10.1007/s004250100661;
RA Martinoia E., Klein M., Geisler M., Bovet L., Forestier C.,
RA Kolukisaoglu H.U., Mueller-Roeber B., Schulz B.;
RT "Multifunctionality of plant ABC transporters -- more than just
RT detoxifiers.";
RL Planta 214:345-355(2002).
RN [6]
RP TISSUE SPECIFICITY.
RX PubMed=15383904; DOI=10.1007/s00239-004-2600-4;
RA Braz A.S.K., Finnegan J., Waterhouse P., Margis R.;
RT "A plant orthologue of RNase L inhibitor (RLI) is induced in plants showing
RT RNA interference.";
RL J. Mol. Evol. 59:20-30(2004).
RN [7]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=18299247; DOI=10.1016/j.tplants.2008.02.001;
RA Verrier P.J., Bird D., Burla B., Dassa E., Forestier C., Geisler M.,
RA Klein M., Kolukisaoglu H.U., Lee Y., Martinoia E., Murphy A., Rea P.A.,
RA Samuels L., Schulz B., Spalding E.J., Yazaki K., Theodoulou F.L.;
RT "Plant ABC proteins - a unified nomenclature and updated inventory.";
RL Trends Plant Sci. 13:151-159(2008).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in roots, stems, leaves, flowers and
CC siliques. {ECO:0000269|PubMed:15383904}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCE family.
CC {ECO:0000305}.
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DR EMBL; AP001307; BAB01911.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE75386.1; -; Genomic_DNA.
DR EMBL; BT003947; AAO41992.1; -; mRNA.
DR EMBL; BT005042; AAO50575.1; -; mRNA.
DR RefSeq; NP_187973.1; NM_112210.3.
DR AlphaFoldDB; Q9LID6; -.
DR SMR; Q9LID6; -.
DR BioGRID; 5902; 1.
DR IntAct; Q9LID6; 1.
DR STRING; 3702.AT3G13640.1; -.
DR PaxDb; Q9LID6; -.
DR PRIDE; Q9LID6; -.
DR ProteomicsDB; 244600; -.
DR EnsemblPlants; AT3G13640.1; AT3G13640.1; AT3G13640.
DR GeneID; 820568; -.
DR Gramene; AT3G13640.1; AT3G13640.1; AT3G13640.
DR KEGG; ath:AT3G13640; -.
DR Araport; AT3G13640; -.
DR TAIR; locus:2091506; AT3G13640.
DR eggNOG; KOG0063; Eukaryota.
DR HOGENOM; CLU_017344_4_1_1; -.
DR InParanoid; Q9LID6; -.
DR OMA; DAYMHPQ; -.
DR OrthoDB; 359213at2759; -.
DR PhylomeDB; Q9LID6; -.
DR PRO; PR:Q9LID6; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9LID6; baseline and differential.
DR Genevisible; Q9LID6; AT.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IBA:GO_Central.
DR GO; GO:0005506; F:iron ion binding; IBA:GO_Central.
DR GO; GO:0043024; F:ribosomal small subunit binding; IBA:GO_Central.
DR GO; GO:0000054; P:ribosomal subunit export from nucleus; IBA:GO_Central.
DR GO; GO:0006413; P:translational initiation; IBA:GO_Central.
DR GO; GO:0006415; P:translational termination; IBA:GO_Central.
DR CDD; cd03236; ABC_RNaseL_inhibitor_domain1; 1.
DR Gene3D; 3.40.50.300; -; 2.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR013283; RLI1.
DR InterPro; IPR034348; RLI_dom_1.
DR InterPro; IPR007209; RNaseL-inhib-like_metal-bd_dom.
DR PANTHER; PTHR19248; PTHR19248; 1.
DR Pfam; PF00005; ABC_tran; 2.
DR Pfam; PF00037; Fer4; 1.
DR Pfam; PF04068; RLI; 1.
DR PRINTS; PR01868; ABCEFAMILY.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; SSF52540; 2.
DR PROSITE; PS00198; 4FE4S_FER_1; 1.
DR PROSITE; PS51379; 4FE4S_FER_2; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 2: Evidence at transcript level;
KW 4Fe-4S; ATP-binding; Iron; Iron-sulfur; Membrane; Metal-binding;
KW Nucleotide-binding; Reference proteome; Repeat; Transport.
FT CHAIN 1..603
FT /note="ABC transporter E family member 1"
FT /id="PRO_0000379137"
FT DOMAIN 7..39
FT /note="4Fe-4S ferredoxin-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00711"
FT DOMAIN 46..75
FT /note="4Fe-4S ferredoxin-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00711"
FT DOMAIN 70..315
FT /note="ABC transporter 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT DOMAIN 344..566
FT /note="ABC transporter 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT BINDING 110..117
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT BINDING 381..388
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ SEQUENCE 603 AA; 68161 MW; B5DE663E568BF543 CRC64;
MSDRLTRIAI VSEDRCKPKK CRQECKKSCP VVKTGKLCIE VGSTSKSAFI SEELCIGCGI
CVKKCPFEAI QIINLPKDLA KDTTHRYGAN GFKLHRLPIP RPGQVLGLVG TNGIGKSTAL
KILAGKLKPN LGRFNTPPDW EEILTHFRGS ELQSYFIRVV EENLKTAIKP QHVDYIKEVV
RGNLGKMLEK LDERGLMEEI CADMELNQVL EREARQVSGG ELQRFAIAAV FVKKADIYMF
DEPSSYLDVR QRLKAAQVIR SLLRHDSYVI VVEHDLSVLD YLSDFVCCLY GKPGAYGVVT
LPFSVREGIN VFLAGFIPTE NLRFRDESLT FRVSETTQEN DGEVKSYARY KYPNMTKQLG
DFKLEVMEGE FTDSQIIVML GENGTGKTTF IRMLAGAFPR EEGVQSEIPE FNVSYKPQGN
DSKRECTVRQ LLHDKIRDAC AHPQFMSDVI RPLQIEQLMD QVVKTLSGGE KQRVAITLCL
GKPADIYLID EPSAHLDSEQ RITASKVIKR FILHAKKTAF IVEHDFIMAT YLADRVIVYE
GQPAVKCIAH SPQSLLSGMN HFLSHLNITF RRDPTNFRPR INKLESIKDK EQKTAGSYYY
LDD
