ID   ATPI_LACSA              Reviewed;         247 AA.
AC   Q56P09;
DT   10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=ATP synthase subunit a, chloroplastic {ECO:0000255|HAMAP-Rule:MF_01393};
DE   AltName: Full=ATP synthase F0 sector subunit a {ECO:0000255|HAMAP-Rule:MF_01393};
DE   AltName: Full=F-ATPase subunit IV {ECO:0000255|HAMAP-Rule:MF_01393};
GN   Name=atpI {ECO:0000255|HAMAP-Rule:MF_01393}; ORFNames=PSC016;
OS   Lactuca sativa (Garden lettuce).
OG   Plastid; Chloroplast.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae;
OC   Lactucinae; Lactuca.
OX   NCBI_TaxID=4236;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=15917497; DOI=10.1093/molbev/msi174;
RA   Kim K.-J., Choi K.-S., Jansen R.K.;
RT   "Two chloroplast DNA inversions originated simultaneously during the early
RT   evolution of the sunflower family (Asteraceae).";
RL   Mol. Biol. Evol. 22:1783-1792(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Cisco;
RX   PubMed=16604461; DOI=10.1007/s11248-005-3997-2;
RA   Kanamoto H., Yamashita A., Asao H., Okumura S., Takase H., Hattori M.,
RA   Yokota A., Tomizawa K.;
RT   "Efficient and stable transformation of Lactuca sativa L. cv. Cisco
RT   (lettuce) plastids.";
RL   Transgenic Res. 15:205-217(2006).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Salinas;
RA   Timme R.E., Kuehl J.V., Boore J.L., Jansen R.K.;
RT   "A comparison of the first two published chloroplast genomes in Asteraceae:
RT   Lactuca and Helianthus.";
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Key component of the proton channel; it plays a direct role
CC       in the translocation of protons across the membrane.
CC       {ECO:0000255|HAMAP-Rule:MF_01393}.
CC   -!- SUBUNIT: F-type ATPases have 2 components, CF(1) - the catalytic core
CC       - and CF(0) - the membrane proton channel. CF(1) has five subunits:
CC       alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main
CC       subunits: a, b, b' and c. {ECO:0000255|HAMAP-Rule:MF_01393}.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast thylakoid membrane
CC       {ECO:0000255|HAMAP-Rule:MF_01393}; Multi-pass membrane protein
CC       {ECO:0000255|HAMAP-Rule:MF_01393}.
CC   -!- SIMILARITY: Belongs to the ATPase A chain family. {ECO:0000255|HAMAP-
CC       Rule:MF_01393}.
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DR   EMBL; AY865171; AAX58146.1; -; Genomic_DNA.
DR   EMBL; DQ383816; ABD47224.1; -; Genomic_DNA.
DR   EMBL; AP007232; BAE47585.1; -; Genomic_DNA.
DR   RefSeq; YP_398320.1; NC_007578.1.
DR   AlphaFoldDB; Q56P09; -.
DR   SMR; Q56P09; -.
DR   GeneID; 3772794; -.
DR   KEGG; lsv:3772794; -.
DR   OrthoDB; 1136313at2759; -.
DR   GO; GO:0009535; C:chloroplast thylakoid membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0045263; C:proton-transporting ATP synthase complex, coupling factor F(o); IEA:UniProtKB-KW.
DR   GO; GO:0046933; F:proton-transporting ATP synthase activity, rotational mechanism; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.20.120.220; -; 1.
DR   HAMAP; MF_01393; ATP_synth_a_bact; 1.
DR   InterPro; IPR045082; ATP_syn_F0_a_bact/chloroplast.
DR   InterPro; IPR000568; ATP_synth_F0_asu.
DR   InterPro; IPR023011; ATP_synth_F0_asu_AS.
DR   InterPro; IPR035908; F0_ATP_A_sf.
DR   PANTHER; PTHR42823; PTHR42823; 1.
DR   Pfam; PF00119; ATP-synt_A; 1.
DR   PRINTS; PR00123; ATPASEA.
DR   SUPFAM; SSF81336; SSF81336; 1.
DR   TIGRFAMs; TIGR01131; ATP_synt_6_or_A; 1.
DR   PROSITE; PS00449; ATPASE_A; 1.
PE   3: Inferred from homology;
KW   ATP synthesis; CF(0); Chloroplast; Hydrogen ion transport; Ion transport;
KW   Membrane; Plastid; Thylakoid; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..247
FT                   /note="ATP synthase subunit a, chloroplastic"
FT                   /id="PRO_0000362565"
FT   TRANSMEM        38..58
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01393"
FT   TRANSMEM        95..115
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01393"
FT   TRANSMEM        134..154
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01393"
FT   TRANSMEM        199..219
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01393"
FT   TRANSMEM        220..240
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01393"
SQ   SEQUENCE   247 AA;  27027 MW;  259C1A643A8DFA24 CRC64;
     MNVLSCSINT LNGLYDISGV EVGQHFYWKI GGFQVHGQVL ITSWVVIAIL LASATLAVRN
     PQTIPTSGQN FFEYVLEFIR DVSKTQIGEE YGPWVPFIGT MFLFIFVSNW SGALLPWKII
     QLPHGELAAP TNDINTTVAL ALLTSVAYFY AGLSKKGLGY FGKYIQPTPI LLPINILEDF
     TKPLSLSFRL FGNILADELV VVVLVSLVPS VVPIPVMFLG LFTSGIQALI FATLAAAYIG
     ESMEGHH