AB1G_ARATH
ID AB1G_ARATH Reviewed; 740 AA.
AC O80946;
DT 27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1998, sequence version 1.
DT 03-AUG-2022, entry version 147.
DE RecName: Full=ABC transporter G family member 1;
DE Short=ABC transporter ABCG.1;
DE Short=AtABCG1;
DE AltName: Full=White-brown complex homolog protein 1;
DE Short=AtWBC1;
GN Name=ABCG1; Synonyms=WBC1; OrderedLocusNames=At2g39350; ORFNames=T16B24.1;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=11346655; DOI=10.1074/jbc.m103104200;
RA Sanchez-Fernandez R., Davies T.G., Coleman J.O., Rea P.A.;
RT "The Arabidopsis thaliana ABC protein superfamily, a complete inventory.";
RL J. Biol. Chem. 276:30231-30244(2001).
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=18299247; DOI=10.1016/j.tplants.2008.02.001;
RA Verrier P.J., Bird D., Burla B., Dassa E., Forestier C., Geisler M.,
RA Klein M., Kolukisaoglu H.U., Lee Y., Martinoia E., Murphy A., Rea P.A.,
RA Samuels L., Schulz B., Spalding E.J., Yazaki K., Theodoulou F.L.;
RT "Plant ABC proteins - a unified nomenclature and updated inventory.";
RL Trends Plant Sci. 13:151-159(2008).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Multi-pass membrane
CC protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCG family.
CC Eye pigment precursor importer (TC 3.A.1.204) subfamily. {ECO:0000305}.
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DR EMBL; AC004697; AAC28975.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC09664.1; -; Genomic_DNA.
DR EMBL; AK117338; BAC42008.1; -; mRNA.
DR PIR; T02567; T02567.
DR RefSeq; NP_181467.1; NM_129492.3.
DR AlphaFoldDB; O80946; -.
DR SMR; O80946; -.
DR BioGRID; 3858; 1.
DR IntAct; O80946; 1.
DR STRING; 3702.AT2G39350.1; -.
DR PaxDb; O80946; -.
DR PRIDE; O80946; -.
DR ProteomicsDB; 244577; -.
DR EnsemblPlants; AT2G39350.1; AT2G39350.1; AT2G39350.
DR GeneID; 818520; -.
DR Gramene; AT2G39350.1; AT2G39350.1; AT2G39350.
DR KEGG; ath:AT2G39350; -.
DR Araport; AT2G39350; -.
DR TAIR; locus:2039682; AT2G39350.
DR eggNOG; KOG0061; Eukaryota.
DR HOGENOM; CLU_000604_57_8_1; -.
DR InParanoid; O80946; -.
DR OMA; TIHQPGM; -.
DR OrthoDB; 1022017at2759; -.
DR PhylomeDB; O80946; -.
DR PRO; PR:O80946; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; O80946; baseline and differential.
DR Genevisible; O80946; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0042626; F:ATPase-coupled transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0010208; P:pollen wall assembly; IGI:TAIR.
DR GO; GO:0009624; P:response to nematode; HEP:TAIR.
DR GO; GO:0055085; P:transmembrane transport; IBA:GO_Central.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC_2_trans.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF01061; ABC2_membrane; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 2: Evidence at transcript level;
KW ATP-binding; Membrane; Nucleotide-binding; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..740
FT /note="ABC transporter G family member 1"
FT /id="PRO_0000240673"
FT TRANSMEM 453..473
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 488..508
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 529..549
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 563..585
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 594..614
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 713..733
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 82..334
FT /note="ABC transporter"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT DOMAIN 434..644
FT /note="ABC transmembrane type-2"
FT BINDING 127..134
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ SEQUENCE 740 AA; 82331 MW; 66D402FB9E376AF5 CRC64;
MARIVAANDD DSMELNTISS IHDSTLGQLL KNVSDVRKMA IGDETPVHES LNQDYNDGYM
RTVPFVLSFD NLTYNVSVRP KLDFRNLFPR RRTEDPEIAQ TARPKTKTLL NNISGETRDG
EIMAVLGASG SGKSTLIDAL ANRIAKGSLK GTVKLNGETL QSRMLKVISA YVMQDDLLFP
MLTVEETLMF AAEFRLPRSL PKSKKKLRVQ ALIDQLGIRN AAKTIIGDEG HRGISGGERR
RVSIGIDIIH DPILLFLDEP TSGLDSTSAF MVVKVLKRIA QSGSIVIMSI HQPSHRVLGL
LDRLIFLSRG HTVYSGSPAS LPRFFTEFGS PIPENENRTE FALDLIRELE GSAGGTRGLI
EFNKKWQEMK KQSNRQPPLT PPSSPYPNLT LKEAIAASIS RGKLVSGGES VAHGGATTNT
TTLAVPAFAN PMWIEIKTLS KRSMLNSRRQ PELFGIRIAS VVITGFILAT VFWRLDNSPK
GVQERLGFFA FAMSTMFYTC ADALPVFLQE RYIFMRETAY NAYRRSSYVL SHAIVSFPSL
IFLSVAFAAT TYWAVGLDGG LTGLLFYCLI ILASFWSGSS FVTFLSGVVP SVMLGYTIVV
AILAYFLLFS GFFINRNRIP DYWIWFHYMS LVKYPYEAVL QNEFSDATKC FVRGVQIFDN
TPLGELPEVM KLKLLGTVSK SLGVTISSTT CLTTGSDILR QQGVVQLSKW NCLFITVAFG
FFFRILFYFT LLLGSKNKRR
