ID   AB1I_ARATH              Reviewed;         229 AA.
AC   Q9C8T1;
DT   24-MAY-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   03-AUG-2022, entry version 134.
DE   RecName: Full=ABC transporter I family member 1;
DE            Short=ABC transporter ABCI.1;
DE            Short=AtABCI1;
DE   AltName: Full=Cytochrome c biogenesis ATP-binding export protein ccmA-like;
DE   AltName: Full=MRP-related protein 3;
DE   AltName: Full=Putative non-intrinsic ABC protein 10;
DE            EC=7.6.2.5;
GN   Name=ABCI1; Synonyms=CCMA, NAP10; OrderedLocusNames=At1g63270;
GN   ORFNames=F9N12.11;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130712; DOI=10.1038/35048500;
RA   Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA   Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA   Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA   Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA   Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA   Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA   Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA   Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA   Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA   Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA   Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA   Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA   Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA   Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA   Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT   "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL   Nature 408:816-820(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=11346655; DOI=10.1074/jbc.m103104200;
RA   Sanchez-Fernandez R., Davies T.G., Coleman J.O., Rea P.A.;
RT   "The Arabidopsis thaliana ABC protein superfamily, a complete inventory.";
RL   J. Biol. Chem. 276:30231-30244(2001).
RN   [4]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=18299247; DOI=10.1016/j.tplants.2008.02.001;
RA   Verrier P.J., Bird D., Burla B., Dassa E., Forestier C., Geisler M.,
RA   Klein M., Kolukisaoglu H.U., Lee Y., Martinoia E., Murphy A., Rea P.A.,
RA   Samuels L., Schulz B., Spalding E.J., Yazaki K., Theodoulou F.L.;
RT   "Plant ABC proteins - a unified nomenclature and updated inventory.";
RL   Trends Plant Sci. 13:151-159(2008).
CC   -!- FUNCTION: Part of the ABC transporter complex CcmAB involved in the
CC       biogenesis of c-type cytochromes; once thought to export heme, this
CC       seems not to be the case, but its exact role is uncertain. Responsible
CC       for energy coupling to the transport system (By similarity).
CC       {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O + heme b(in) = ADP + H(+) + heme b(out) + phosphate;
CC         Xref=Rhea:RHEA:19261, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:60344,
CC         ChEBI:CHEBI:456216; EC=7.6.2.5;
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Peripheral membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCI family.
CC       {ECO:0000305}.
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DR   EMBL; AC022355; AAG52155.1; -; Genomic_DNA.
DR   EMBL; CP002684; AEE34080.1; -; Genomic_DNA.
DR   PIR; E96658; E96658.
DR   RefSeq; NP_176516.1; NM_105006.3.
DR   AlphaFoldDB; Q9C8T1; -.
DR   SMR; Q9C8T1; -.
DR   BioGRID; 27854; 1.
DR   IntAct; Q9C8T1; 1.
DR   STRING; 3702.AT1G63270.1; -.
DR   TCDB; 3.A.1.107.2; the atp-binding cassette (abc) superfamily.
DR   PaxDb; Q9C8T1; -.
DR   PRIDE; Q9C8T1; -.
DR   ProteomicsDB; 245083; -.
DR   EnsemblPlants; AT1G63270.1; AT1G63270.1; AT1G63270.
DR   GeneID; 842633; -.
DR   Gramene; AT1G63270.1; AT1G63270.1; AT1G63270.
DR   KEGG; ath:AT1G63270; -.
DR   Araport; AT1G63270; -.
DR   TAIR; locus:2038478; AT1G63270.
DR   eggNOG; KOG0059; Eukaryota.
DR   HOGENOM; CLU_000604_1_2_1; -.
DR   InParanoid; Q9C8T1; -.
DR   OMA; NLAWLCA; -.
DR   OrthoDB; 1208859at2759; -.
DR   PhylomeDB; Q9C8T1; -.
DR   BioCyc; ARA:AT1G63270-MON; -.
DR   PRO; PR:Q9C8T1; -.
DR   Proteomes; UP000006548; Chromosome 1.
DR   ExpressionAtlas; Q9C8T1; baseline and differential.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015439; F:ABC-type heme transporter activity; IEA:UniProtKB-EC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR005895; ABC_transptr_haem_export_CcmA.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR43499; PTHR43499; 1.
DR   Pfam; PF00005; ABC_tran; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR01189; ccmA; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
DR   PROSITE; PS51243; CCMA; 1.
PE   2: Evidence at transcript level;
KW   ATP-binding; Cytochrome c-type biogenesis; Hydrolase; Membrane;
KW   Nucleotide-binding; Reference proteome; Translocase; Transport.
FT   CHAIN           1..229
FT                   /note="ABC transporter I family member 1"
FT                   /id="PRO_0000092230"
FT   DOMAIN          11..228
FT                   /note="ABC transporter"
FT   BINDING         43..50
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   229 AA;  25976 MW;  48B925CC1ED796BB CRC64;
     MSIRRPQIPR LLLQNVSCMR NAQQILRHVN VSLHDGGALV LTGTNGSGKS TFLRMLAGFS
     KPSAGEILWN GHDITQSGIF QQYKLQLNWI SLKDAIKERF TVLDNVQWFE LLENKIGKAQ
     PALELMGLGR LVKEKSRMLS MGQRKRLQLA RLLAIDRPIW LLDEPSVALD DEGVRLLEYI
     IAEHRKKGGI VIVATHLPID IEDAMILRLP PRFPRKMTLI DMLDRADIS