ID   RNKA_CERCA              Reviewed;         138 AA.
AC   Q9NDV2;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   25-MAY-2022, entry version 37.
DE   RecName: Full=Ribonuclease kappa-A;
DE            Short=RNase K-A;
DE            Short=RNase kappa-A;
DE            EC=3.1.-.-;
DE   Flags: Precursor;
OS   Ceratitis capitata (Mediterranean fruit fly) (Tephritis capitata).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Tephritoidea;
OC   Tephritidae; Ceratitis; Ceratitis.
OX   NCBI_TaxID=7213;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, AND ENZYME ACTIVITY.
RX   PubMed=10696591; DOI=10.1016/s0965-1748(99)00112-5;
RA   Sideris D.C., Rampias T.N., Fragoulis E.G.;
RT   "Isolation and sequencing of a cDNA encoding for a ribonuclease from the
RT   insect Ceratitis capitata.";
RL   Insect Biochem. Mol. Biol. 30:153-161(2000).
CC   -!- FUNCTION: Endoribonuclease. {ECO:0000269|PubMed:10696591}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the RNase K family. {ECO:0000305}.
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DR   EMBL; Y15384; CAB77385.1; -; mRNA.
DR   AlphaFoldDB; Q9NDV2; -.
DR   SMR; Q9NDV2; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004521; F:endoribonuclease activity; ISS:UniProtKB.
PE   2: Evidence at transcript level;
KW   Endonuclease; Hydrolase; Membrane; Nuclease; Signal; Transmembrane;
KW   Transmembrane helix.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000255"
FT   CHAIN           25..138
FT                   /note="Ribonuclease kappa-A"
FT                   /id="PRO_5000147249"
FT   TOPO_DOM        25..75
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        76..96
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        97..138
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   138 AA;  15925 MW;  4FACA19FA8F7659D CRC64;
     MVLYFSPVLT FFLANFFNSK STTTENLQVF LVENQHRDSK RKINPTFSKK GIEVRQQNEN
     LWSKIVALRF DYSVWGIIQL VLMMGLFFYI NSVALIEDLP IDEEFNSVEE FYTAATSAYN
     QNAYTVGLPV HLCAYASI