RNKA_DANRE
ID RNKA_DANRE Reviewed; 101 AA.
AC Q0P467;
DT 22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT 19-SEP-2006, sequence version 1.
DT 03-AUG-2022, entry version 79.
DE RecName: Full=Ribonuclease kappa-A;
DE Short=RNase K-A;
DE Short=RNase kappa-A;
DE EC=3.1.-.-;
GN Name=rnaseka; ORFNames=zgc:153350;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Ovary;
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Endoribonuclease which preferentially cleaves ApU and ApG
CC phosphodiester bonds. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the RNase K family. {ECO:0000305}.
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DR EMBL; BC122250; AAI22251.1; -; mRNA.
DR RefSeq; NP_001038870.1; NM_001045405.2.
DR AlphaFoldDB; Q0P467; -.
DR SMR; Q0P467; -.
DR STRING; 7955.ENSDARP00000091898; -.
DR PaxDb; Q0P467; -.
DR Ensembl; ENSDART00000101124; ENSDARP00000091898; ENSDARG00000069461.
DR GeneID; 751692; -.
DR KEGG; dre:751692; -.
DR CTD; 751692; -.
DR ZFIN; ZDB-GENE-060825-301; rnaseka.
DR eggNOG; ENOG502S351; Eukaryota.
DR GeneTree; ENSGT00390000009664; -.
DR HOGENOM; CLU_140554_2_1_1; -.
DR InParanoid; Q0P467; -.
DR OMA; SQNAYNC; -.
DR OrthoDB; 1615928at2759; -.
DR PhylomeDB; Q0P467; -.
DR TreeFam; TF300182; -.
DR PRO; PR:Q0P467; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Chromosome 7.
DR Bgee; ENSDARG00000069461; Expressed in pharyngeal gill and 27 other tissues.
DR ExpressionAtlas; Q0P467; baseline and differential.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0004521; F:endoribonuclease activity; ISS:UniProtKB.
DR InterPro; IPR026770; RNase_K.
DR PANTHER; PTHR31733; PTHR31733; 1.
PE 3: Inferred from homology;
KW Endonuclease; Hydrolase; Membrane; Nuclease; Reference proteome;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..101
FT /note="Ribonuclease kappa-A"
FT /id="PRO_0000344223"
FT TRANSMEM 13..33
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 68..88
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 101 AA; 11266 MW; 2E2A48E11F0648AC CRC64;
MVSLLFCGPK LAACGLVLSI WGVIMLALLG IFFTTHSAIL IEDVPLTEED LHSQDTPPQS
VYKLYNQVGY NCFIAAVIYV GIGFLSFCQV RLNKRKEYLV H