ID   RNKB_DANRE              Reviewed;         101 AA.
AC   Q0P442;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   19-SEP-2006, sequence version 1.
DT   03-AUG-2022, entry version 80.
DE   RecName: Full=Ribonuclease kappa-B;
DE            Short=RNase K-B;
DE            Short=RNase kappa-B;
DE            EC=3.1.-.-;
GN   Name=rnasekb; ORFNames=zgc:153424;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Larval eye;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Endoribonuclease which preferentially cleaves ApU and ApG
CC       phosphodiester bonds. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the RNase K family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC122286; AAI22287.1; -; mRNA.
DR   RefSeq; NP_001038840.1; NM_001045375.1.
DR   AlphaFoldDB; Q0P442; -.
DR   SMR; Q0P442; -.
DR   STRING; 7955.ENSDARP00000091585; -.
DR   PaxDb; Q0P442; -.
DR   Ensembl; ENSDART00000163908; ENSDARP00000138622; ENSDARG00000104458.
DR   GeneID; 336290; -.
DR   KEGG; dre:336290; -.
DR   CTD; 336290; -.
DR   ZFIN; ZDB-GENE-060825-160; rnasekb.
DR   eggNOG; ENOG502S351; Eukaryota.
DR   GeneTree; ENSGT00390000009664; -.
DR   HOGENOM; CLU_140554_2_1_1; -.
DR   InParanoid; Q0P442; -.
DR   OMA; RQVGINC; -.
DR   OrthoDB; 1615928at2759; -.
DR   PhylomeDB; Q0P442; -.
DR   TreeFam; TF300182; -.
DR   PRO; PR:Q0P442; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 10.
DR   Bgee; ENSDARG00000104458; Expressed in brain and 27 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004521; F:endoribonuclease activity; ISS:UniProtKB.
DR   InterPro; IPR026770; RNase_K.
DR   PANTHER; PTHR31733; PTHR31733; 1.
PE   3: Inferred from homology;
KW   Endonuclease; Hydrolase; Membrane; Nuclease; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..101
FT                   /note="Ribonuclease kappa-B"
FT                   /id="PRO_0000344224"
FT   TRANSMEM        13..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        68..88
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   101 AA;  11046 MW;  DCE504FFDF3EDBB2 CRC64;
     MPSLLFCGPK LAACGIVLSV WGVIMLSMLG IFFSAKSAVL IEDVPFTEED IRNDKDPPQI
     IYGLYNQVGI NCFIAAAIYV GVGAVSLCQV RLNKRQEYMV T