ID   RNKB_XENLA              Reviewed;         101 AA.
AC   Q566G2;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   10-MAY-2005, sequence version 1.
DT   03-AUG-2022, entry version 43.
DE   RecName: Full=Ribonuclease kappa-B;
DE            Short=RNase K-B;
DE            Short=RNase kappa-B;
DE            EC=3.1.-.-;
GN   Name=rnasek-b;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Eye;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Endoribonuclease which preferentially cleaves ApU and ApG
CC       phosphodiester bonds. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the RNase K family. {ECO:0000305}.
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DR   EMBL; BC093561; AAH93561.1; -; mRNA.
DR   RefSeq; NP_001090277.1; NM_001096808.1.
DR   AlphaFoldDB; Q566G2; -.
DR   SMR; Q566G2; -.
DR   DNASU; 779185; -.
DR   GeneID; 779185; -.
DR   KEGG; xla:779185; -.
DR   CTD; 779185; -.
DR   Xenbase; XB-GENE-6252970; rnasek.L.
DR   OMA; RQVGINC; -.
DR   OrthoDB; 1615928at2759; -.
DR   Proteomes; UP000186698; Chromosome 3L.
DR   Bgee; 779185; Expressed in brain and 19 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004521; F:endoribonuclease activity; ISS:UniProtKB.
DR   InterPro; IPR026770; RNase_K.
DR   PANTHER; PTHR31733; PTHR31733; 1.
PE   3: Inferred from homology;
KW   Endonuclease; Hydrolase; Membrane; Nuclease; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..101
FT                   /note="Ribonuclease kappa-B"
FT                   /id="PRO_0000344226"
FT   TRANSMEM        13..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        68..88
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   101 AA;  11346 MW;  2C8C25D5E021BD61 CRC64;
     MVSLLCCGPK LAACGIVLSV WGVIMLVLLG VFFNVHSAVL IEDVPFTEAD MFEDPNPPAK
     MYRLYEQVSY NCFIAAAIYI VLGGFSFCQV RLNKRKEYMV R