ID   RNK_ECO57               Reviewed;         136 AA.
AC   P0AFW6; P40679;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   20-DEC-2005, sequence version 1.
DT   03-AUG-2022, entry version 91.
DE   RecName: Full=Regulator of nucleoside diphosphate kinase {ECO:0000255|HAMAP-Rule:MF_00954};
GN   Name=rnk {ECO:0000255|HAMAP-Rule:MF_00954};
GN   OrderedLocusNames=Z0754, ECs0649;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA   Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA   Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA   Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA   Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA   Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA   Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA   Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT   genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- FUNCTION: May act as an anti-Gre factor. {ECO:0000255|HAMAP-
CC       Rule:MF_00954}.
CC   -!- SUBUNIT: Interacts with the RNA polymerase. {ECO:0000255|HAMAP-
CC       Rule:MF_00954}.
CC   -!- SIMILARITY: Belongs to the Rnk family. {ECO:0000255|HAMAP-
CC       Rule:MF_00954}.
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DR   EMBL; AE005174; AAG54945.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB34072.1; -; Genomic_DNA.
DR   PIR; A90710; A90710.
DR   PIR; E85560; E85560.
DR   RefSeq; NP_308676.1; NC_002695.1.
DR   RefSeq; WP_000089731.1; NZ_SWKA01000005.1.
DR   AlphaFoldDB; P0AFW6; -.
DR   SMR; P0AFW6; -.
DR   STRING; 155864.EDL933_0683; -.
DR   EnsemblBacteria; AAG54945; AAG54945; Z0754.
DR   EnsemblBacteria; BAB34072; BAB34072; ECs_0649.
DR   GeneID; 66671115; -.
DR   GeneID; 917008; -.
DR   KEGG; ece:Z0754; -.
DR   KEGG; ecs:ECs_0649; -.
DR   PATRIC; fig|386585.9.peg.760; -.
DR   eggNOG; COG0782; Bacteria.
DR   HOGENOM; CLU_120358_1_1_6; -.
DR   OMA; VHCREES; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0070063; F:RNA polymerase binding; IEA:InterPro.
DR   GO; GO:0032784; P:regulation of DNA-templated transcription, elongation; IEA:InterPro.
DR   Gene3D; 3.10.50.30; -; 1.
DR   HAMAP; MF_00954; Rnk; 1.
DR   InterPro; IPR036953; GreA/GreB_C_sf.
DR   InterPro; IPR028625; Rnk.
DR   InterPro; IPR029462; Rnk_N.
DR   InterPro; IPR001437; Tscrpt_elong_fac_GreA/B_C.
DR   InterPro; IPR023459; Tscrpt_elong_fac_GreA/B_fam.
DR   PANTHER; PTHR30437; PTHR30437; 1.
DR   Pfam; PF01272; GreA_GreB; 1.
DR   Pfam; PF14760; Rnk_N; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..136
FT                   /note="Regulator of nucleoside diphosphate kinase"
FT                   /id="PRO_0000097388"
SQ   SEQUENCE   136 AA;  14927 MW;  7043926623BA5E1E CRC64;
     MSRPTIIIND LDAERIDILL EQPAYAGLPI ADALNAELDR AQMCSPEEMP HDVVTMNSRV
     KFRNLSDGEV RVRTLVYPAK MTDSNTQLSV MAPVGAALLG LRVGDSIHWE LPGGVATHLE
     VLELEYQPEA AGDYLL