ID   RNK_SHIFL               Reviewed;         136 AA.
AC   P0AFW7; P40679;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   20-DEC-2005, sequence version 1.
DT   25-MAY-2022, entry version 95.
DE   RecName: Full=Regulator of nucleoside diphosphate kinase {ECO:0000255|HAMAP-Rule:MF_00954};
GN   Name=rnk {ECO:0000255|HAMAP-Rule:MF_00954};
GN   OrderedLocusNames=SF0528, S0534;
OS   Shigella flexneri.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=623;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=301 / Serotype 2a;
RX   PubMed=12384590; DOI=10.1093/nar/gkf566;
RA   Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA   Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA   Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA   Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT   "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT   through comparison with genomes of Escherichia coli K12 and O157.";
RL   Nucleic Acids Res. 30:4432-4441(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX   PubMed=12704152; DOI=10.1128/iai.71.5.2775-2786.2003;
RA   Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G.,
RA   Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T.,
RA   Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.;
RT   "Complete genome sequence and comparative genomics of Shigella flexneri
RT   serotype 2a strain 2457T.";
RL   Infect. Immun. 71:2775-2786(2003).
CC   -!- FUNCTION: May act as an anti-Gre factor. {ECO:0000255|HAMAP-
CC       Rule:MF_00954}.
CC   -!- SUBUNIT: Interacts with the RNA polymerase. {ECO:0000255|HAMAP-
CC       Rule:MF_00954}.
CC   -!- SIMILARITY: Belongs to the Rnk family. {ECO:0000255|HAMAP-
CC       Rule:MF_00954}.
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DR   EMBL; AE005674; AAN42174.1; -; Genomic_DNA.
DR   EMBL; AE014073; AAP16045.1; -; Genomic_DNA.
DR   RefSeq; NP_706467.1; NC_004337.2.
DR   RefSeq; WP_000089731.1; NZ_WPGW01000089.1.
DR   AlphaFoldDB; P0AFW7; -.
DR   SMR; P0AFW7; -.
DR   STRING; 198214.SF0528; -.
DR   EnsemblBacteria; AAN42174; AAN42174; SF0528.
DR   EnsemblBacteria; AAP16045; AAP16045; S0534.
DR   GeneID; 1023415; -.
DR   GeneID; 66671115; -.
DR   KEGG; sfl:SF0528; -.
DR   KEGG; sfx:S0534; -.
DR   PATRIC; fig|198214.7.peg.614; -.
DR   HOGENOM; CLU_120358_1_1_6; -.
DR   OMA; VHCREES; -.
DR   OrthoDB; 1536415at2; -.
DR   Proteomes; UP000001006; Chromosome.
DR   Proteomes; UP000002673; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0070063; F:RNA polymerase binding; IEA:InterPro.
DR   GO; GO:0032784; P:regulation of DNA-templated transcription, elongation; IEA:InterPro.
DR   Gene3D; 3.10.50.30; -; 1.
DR   HAMAP; MF_00954; Rnk; 1.
DR   InterPro; IPR036953; GreA/GreB_C_sf.
DR   InterPro; IPR028625; Rnk.
DR   InterPro; IPR029462; Rnk_N.
DR   InterPro; IPR001437; Tscrpt_elong_fac_GreA/B_C.
DR   InterPro; IPR023459; Tscrpt_elong_fac_GreA/B_fam.
DR   PANTHER; PTHR30437; PTHR30437; 1.
DR   Pfam; PF01272; GreA_GreB; 1.
DR   Pfam; PF14760; Rnk_N; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..136
FT                   /note="Regulator of nucleoside diphosphate kinase"
FT                   /id="PRO_0000097389"
SQ   SEQUENCE   136 AA;  14927 MW;  7043926623BA5E1E CRC64;
     MSRPTIIIND LDAERIDILL EQPAYAGLPI ADALNAELDR AQMCSPEEMP HDVVTMNSRV
     KFRNLSDGEV RVRTLVYPAK MTDSNTQLSV MAPVGAALLG LRVGDSIHWE LPGGVATHLE
     VLELEYQPEA AGDYLL