ID   RNP1_HALSA              Reviewed;         123 AA.
AC   O24785; Q9HPC6;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   25-MAY-2022, entry version 120.
DE   RecName: Full=Ribonuclease P protein component 1 {ECO:0000255|HAMAP-Rule:MF_00754};
DE            Short=RNase P component 1 {ECO:0000255|HAMAP-Rule:MF_00754};
DE            EC=3.1.26.5 {ECO:0000255|HAMAP-Rule:MF_00754};
DE   AltName: Full=Rpp29 {ECO:0000255|HAMAP-Rule:MF_00754};
GN   Name=rnp1 {ECO:0000255|HAMAP-Rule:MF_00754}; OrderedLocusNames=VNG_1699C;
OS   Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)
OS   (Halobacterium halobium).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Halobacteriaceae; Halobacterium.
OX   NCBI_TaxID=64091;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8876975; DOI=10.1080/15216549600201402;
RA   Miyokawa T., Urayama T., Shimooka K., Itoh T.;
RT   "Organization and nucleotide sequences of ten ribosomal protein genes from
RT   the region equivalent to the S10 operon in the archaebacterium,
RT   Halobacterium halobium.";
RL   Biochem. Mol. Biol. Int. 39:1209-1220(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700922 / JCM 11081 / NRC-1;
RX   PubMed=11016950; DOI=10.1073/pnas.190337797;
RA   Ng W.V., Kennedy S.P., Mahairas G.G., Berquist B., Pan M., Shukla H.D.,
RA   Lasky S.R., Baliga N.S., Thorsson V., Sbrogna J., Swartzell S., Weir D.,
RA   Hall J., Dahl T.A., Welti R., Goo Y.A., Leithauser B., Keller K., Cruz R.,
RA   Danson M.J., Hough D.W., Maddocks D.G., Jablonski P.E., Krebs M.P.,
RA   Angevine C.M., Dale H., Isenbarger T.A., Peck R.F., Pohlschroder M.,
RA   Spudich J.L., Jung K.-H., Alam M., Freitas T., Hou S., Daniels C.J.,
RA   Dennis P.P., Omer A.D., Ebhardt H., Lowe T.M., Liang P., Riley M., Hood L.,
RA   DasSarma S.;
RT   "Genome sequence of Halobacterium species NRC-1.";
RL   Proc. Natl. Acad. Sci. U.S.A. 97:12176-12181(2000).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 8-84.
RX   PubMed=2470481; DOI=10.1139/m89-023;
RA   Spiridonova V.A., Akhmanova A.S., Kagramanova V.K., Koepke A.K.E.,
RA   Mankin A.S.;
RT   "Ribosomal protein gene cluster of Halobacterium halobium: nucleotide
RT   sequence of the genes coding for S3 and L29 equivalent ribosomal
RT   proteins.";
RL   Can. J. Microbiol. 35:153-159(1989).
CC   -!- FUNCTION: Part of ribonuclease P, a protein complex that generates
CC       mature tRNA molecules by cleaving their 5'-ends. {ECO:0000255|HAMAP-
CC       Rule:MF_00754}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Endonucleolytic cleavage of RNA, removing 5'-extranucleotides
CC         from tRNA precursor.; EC=3.1.26.5; Evidence={ECO:0000255|HAMAP-
CC         Rule:MF_00754};
CC   -!- SUBUNIT: Consists of a catalytic RNA component and at least 4-5 protein
CC       subunits. {ECO:0000255|HAMAP-Rule:MF_00754}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00754}.
CC   -!- SIMILARITY: Belongs to the eukaryotic/archaeal RNase P protein
CC       component 1 family. {ECO:0000255|HAMAP-Rule:MF_00754}.
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DR   EMBL; AB006961; BAA22278.1; -; Genomic_DNA.
DR   EMBL; AE004437; AAG19944.1; -; Genomic_DNA.
DR   PIR; D84322; D84322.
DR   PIR; T43824; T43824.
DR   RefSeq; WP_010903242.1; NC_002607.1.
DR   AlphaFoldDB; O24785; -.
DR   SMR; O24785; -.
DR   STRING; 64091.VNG_1699C; -.
DR   PaxDb; O24785; -.
DR   EnsemblBacteria; AAG19944; AAG19944; VNG_1699C.
DR   GeneID; 5954228; -.
DR   GeneID; 62887094; -.
DR   KEGG; hal:VNG_1699C; -.
DR   PATRIC; fig|64091.14.peg.1296; -.
DR   HOGENOM; CLU_107020_0_0_2; -.
DR   InParanoid; O24785; -.
DR   OMA; RVVMVPK; -.
DR   OrthoDB; 124913at2157; -.
DR   PhylomeDB; O24785; -.
DR   Proteomes; UP000000554; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0030677; C:ribonuclease P complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0004526; F:ribonuclease P activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0001682; P:tRNA 5'-leader removal; IEA:UniProtKB-UniRule.
DR   Gene3D; 2.30.30.210; -; 1.
DR   HAMAP; MF_00754; RNase_P_1; 1.
DR   InterPro; IPR036980; RNase_P/MRP_Rpp29_sf.
DR   InterPro; IPR023538; RNP1.
DR   InterPro; IPR023534; Rof/RNase_P-like.
DR   InterPro; IPR002730; Rpp29/RNP1.
DR   Pfam; PF01868; RNase_P-MRP_p29; 1.
DR   SMART; SM00538; POP4; 1.
DR   SUPFAM; SSF101744; SSF101744; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Endonuclease; Hydrolase; Nuclease; Reference proteome;
KW   tRNA processing.
FT   CHAIN           1..123
FT                   /note="Ribonuclease P protein component 1"
FT                   /id="PRO_0000128427"
FT   REGION          73..93
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   123 AA;  13135 MW;  E6941EE7E22237EB CRC64;
     MTTITPESLP RHELLGLHAR VAADTDQSRV GIAGRVVDET MQTVVLRTAS GVAQVPKKGA
     TFEFRLTDEA AAPDNGVGTA FKPAGGETRQ TTGESVAYVT VDGGRLLSRP ERRSENGVDS
     KWR