RNP3_PYRAB
ID RNP3_PYRAB Reviewed; 212 AA.
AC Q9UXX7; G8ZK97;
DT 13-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 25-MAY-2022, entry version 100.
DE RecName: Full=Ribonuclease P protein component 3 {ECO:0000255|HAMAP-Rule:MF_00756};
DE Short=RNase P component 3 {ECO:0000255|HAMAP-Rule:MF_00756};
DE EC=3.1.26.5 {ECO:0000255|HAMAP-Rule:MF_00756};
DE AltName: Full=Rpp30 {ECO:0000255|HAMAP-Rule:MF_00756};
GN Name=rnp3 {ECO:0000255|HAMAP-Rule:MF_00756}; OrderedLocusNames=PYRAB17310;
GN ORFNames=PAB1136;
OS Pyrococcus abyssi (strain GE5 / Orsay).
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Pyrococcus.
OX NCBI_TaxID=272844;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GE5 / Orsay;
RX PubMed=12622808; DOI=10.1046/j.1365-2958.2003.03381.x;
RA Cohen G.N., Barbe V., Flament D., Galperin M., Heilig R., Lecompte O.,
RA Poch O., Prieur D., Querellou J., Ripp R., Thierry J.-C., Van der Oost J.,
RA Weissenbach J., Zivanovic Y., Forterre P.;
RT "An integrated analysis of the genome of the hyperthermophilic archaeon
RT Pyrococcus abyssi.";
RL Mol. Microbiol. 47:1495-1512(2003).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=GE5 / Orsay;
RX PubMed=22057919; DOI=10.1007/s00284-011-0035-x;
RA Gao J., Wang J.;
RT "Re-annotation of two hyperthermophilic archaea Pyrococcus abyssi GE5 and
RT Pyrococcus furiosus DSM 3638.";
RL Curr. Microbiol. 64:118-129(2012).
CC -!- FUNCTION: Part of ribonuclease P, a protein complex that generates
CC mature tRNA molecules by cleaving their 5'-ends. {ECO:0000255|HAMAP-
CC Rule:MF_00756}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Endonucleolytic cleavage of RNA, removing 5'-extranucleotides
CC from tRNA precursor.; EC=3.1.26.5; Evidence={ECO:0000255|HAMAP-
CC Rule:MF_00756};
CC -!- SUBUNIT: Consists of a catalytic RNA component and at least 4-5 protein
CC subunits. {ECO:0000255|HAMAP-Rule:MF_00756}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00756}.
CC -!- SIMILARITY: Belongs to the eukaryotic/archaeal RNase P protein
CC component 3 family. {ECO:0000255|HAMAP-Rule:MF_00756}.
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DR EMBL; AJ248288; CAB50636.1; -; Genomic_DNA.
DR EMBL; HE613800; CCE71204.1; -; Genomic_DNA.
DR PIR; F75024; F75024.
DR RefSeq; WP_010868850.1; NC_000868.1.
DR AlphaFoldDB; Q9UXX7; -.
DR SMR; Q9UXX7; -.
DR STRING; 272844.PAB1136; -.
DR EnsemblBacteria; CAB50636; CAB50636; PAB1136.
DR GeneID; 1496033; -.
DR KEGG; pab:PAB1136; -.
DR PATRIC; fig|272844.11.peg.1849; -.
DR eggNOG; arCOG00307; Archaea.
DR HOGENOM; CLU_1302679_0_0_2; -.
DR OMA; WFDEVVF; -.
DR OrthoDB; 66325at2157; -.
DR PhylomeDB; Q9UXX7; -.
DR Proteomes; UP000000810; Chromosome.
DR Proteomes; UP000009139; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0030677; C:ribonuclease P complex; IEA:UniProtKB-UniRule.
DR GO; GO:0004526; F:ribonuclease P activity; IEA:UniProtKB-UniRule.
DR GO; GO:0001682; P:tRNA 5'-leader removal; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00756; RNase_P_3; 1.
DR InterPro; IPR016195; Pol/histidinol_Pase-like.
DR InterPro; IPR023539; RNase_P_comp-3_arc.
DR InterPro; IPR002738; RNase_P_p30.
DR Pfam; PF01876; RNase_P_p30; 1.
DR SUPFAM; SSF89550; SSF89550; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Endonuclease; Hydrolase; Nuclease; tRNA processing.
FT CHAIN 1..212
FT /note="Ribonuclease P protein component 3"
FT /id="PRO_0000140044"
SQ SEQUENCE 212 AA; 24365 MW; D170AE61916E5CA8 CRC64;
MAGGGGLKFV EMDVRNDDAY KLAKEWFDEV VFSVKFQDSI DKELLREAER NYGLVAILLV
NPRLSIVKEA VQRFKQNYLI YVESSDLRTI RYSIERGVDA IISPWVGRKD PGIDHTLARM
MAKKGVALGF SLRPLLEASP YDKANILKFM RKAWQLTNKY KVKRFITSSA NEKWHIRWPR
DLATLGIIIG MEVQQAKAAL STYPDIILKR LK
