AB21I_ARATH
ID AB21I_ARATH Reviewed; 282 AA.
AC Q9XF19; Q8LBC2;
DT 03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1999, sequence version 1.
DT 03-AUG-2022, entry version 142.
DE RecName: Full=ABC transporter I family member 21;
DE Short=ABC transporter ABCI.21;
DE Short=AtABCI21;
DE AltName: Full=GCN-related protein 1;
DE AltName: Full=Non-intrinsic ABC protein 2;
GN Name=ABCI21; Synonyms=NAP2, POP1; OrderedLocusNames=At5g44110;
GN ORFNames=MLN1.3;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), INDUCTION, TISSUE SPECIFICITY, AND
RP SUBCELLULAR LOCATION.
RC STRAIN=cv. Wassilewskija;
RX AGRICOLA=IND43814144; DOI=10.1016/j.plantsci.2006.02.014;
RA Marin E., Divol F., Bechtold N., Vavasseur A., Nussaume L., Forestier C.;
RT "Molecular characterization of three Arabidopsis soluble ABC proteins which
RT expression is induced by sugars.";
RL Plant Sci. 171:84-90(2006).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9330910; DOI=10.1093/dnares/4.3.215;
RA Sato S., Kotani H., Nakamura Y., Kaneko T., Asamizu E., Fukami M.,
RA Miyajima N., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. I. Sequence
RT features of the 1.6 Mb regions covered by twenty physically assigned P1
RT clones.";
RL DNA Res. 4:215-230(1997).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [7]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=11346655; DOI=10.1074/jbc.m103104200;
RA Sanchez-Fernandez R., Davies T.G., Coleman J.O., Rea P.A.;
RT "The Arabidopsis thaliana ABC protein superfamily, a complete inventory.";
RL J. Biol. Chem. 276:30231-30244(2001).
RN [8]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=18299247; DOI=10.1016/j.tplants.2008.02.001;
RA Verrier P.J., Bird D., Burla B., Dassa E., Forestier C., Geisler M.,
RA Klein M., Kolukisaoglu H.U., Lee Y., Martinoia E., Murphy A., Rea P.A.,
RA Samuels L., Schulz B., Spalding E.J., Yazaki K., Theodoulou F.L.;
RT "Plant ABC proteins - a unified nomenclature and updated inventory.";
RL Trends Plant Sci. 13:151-159(2008).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|Ref.1}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=A number of isoforms are produced. According to EST
CC sequences.;
CC Name=1;
CC IsoId=Q9XF19-1; Sequence=Displayed;
CC -!- TISSUE SPECIFICITY: Expressed in root elongating zone and root
CC meristem, as well as in elongating etiolated hypocotyls.
CC {ECO:0000269|Ref.1}.
CC -!- INDUCTION: By sucrose. {ECO:0000269|Ref.1}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCI family.
CC {ECO:0000305}.
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DR EMBL; AF127664; AAD20643.1; -; mRNA.
DR EMBL; AB005239; BAB10978.1; -; Genomic_DNA.
DR EMBL; CP002688; AED95059.1; -; Genomic_DNA.
DR EMBL; BT006201; AAP12850.1; -; mRNA.
DR EMBL; AY087299; AAM64851.1; -; mRNA.
DR EMBL; AK228176; BAF00132.1; -; mRNA.
DR RefSeq; NP_199224.1; NM_123778.3. [Q9XF19-1]
DR AlphaFoldDB; Q9XF19; -.
DR SMR; Q9XF19; -.
DR BioGRID; 19684; 2.
DR IntAct; Q9XF19; 2.
DR STRING; 3702.AT5G44110.1; -.
DR PaxDb; Q9XF19; -.
DR PRIDE; Q9XF19; -.
DR ProteomicsDB; 244496; -. [Q9XF19-1]
DR EnsemblPlants; AT5G44110.1; AT5G44110.1; AT5G44110. [Q9XF19-1]
DR GeneID; 834434; -.
DR Gramene; AT5G44110.1; AT5G44110.1; AT5G44110. [Q9XF19-1]
DR KEGG; ath:AT5G44110; -.
DR Araport; AT5G44110; -.
DR TAIR; locus:2167644; AT5G44110.
DR eggNOG; KOG2355; Eukaryota.
DR HOGENOM; CLU_057592_1_0_1; -.
DR InParanoid; Q9XF19; -.
DR OMA; WATHLYY; -.
DR PhylomeDB; Q9XF19; -.
DR PRO; PR:Q9XF19; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9XF19; baseline and differential.
DR Genevisible; Q9XF19; AT.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0010218; P:response to far red light; IEP:TAIR.
DR GO; GO:0010114; P:response to red light; IEP:TAIR.
DR Gene3D; 3.40.50.300; -; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; ATP-binding; Cytoplasm; Nucleotide-binding;
KW Reference proteome; Transport.
FT CHAIN 1..282
FT /note="ABC transporter I family member 21"
FT /id="PRO_0000250654"
FT DOMAIN 13..248
FT /note="ABC transporter"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT BINDING 46..53
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ SEQUENCE 282 AA; 31360 MW; 6F0E88F3EFDB1577 CRC64;
MAEKNASAVD GAIRVSGMQF SYDVQDPIFF DFNLDLPAGS RCLLVGANGS GKTTLLKILA
GKHMVGGKNV VQVLDRSAFH DTELVCSGDL SYLGGSWSKT AGSAGDIPLQ GDFSAEHMIF
GVEGIDPFRR EKLIDLLDIN LQWRMHKVSD GQRRRVQICM GLLHPFKVLL LDEVTVDLDV
VARMDLLEFF KEECEQRGAT IVYATHIFDG LETWASHLAY INGGELKLSA KLDEIKDLKT
SPNLLSVVEA WLRSETKVEK KTKKKPVVTS PFMSSRQMAY YR
