AB24G_ARATH
ID AB24G_ARATH Reviewed; 1109 AA.
AC Q9MAG3; Q0WU00;
DT 27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT 08-FEB-2011, sequence version 2.
DT 03-AUG-2022, entry version 141.
DE RecName: Full=ABC transporter G family member 24;
DE Short=ABC transporter ABCG.24;
DE Short=AtABCG24;
DE AltName: Full=Probable white-brown complex homolog protein 25;
DE Short=AtWBC25;
GN Name=ABCG24; Synonyms=WBC25; OrderedLocusNames=At1g53390;
GN ORFNames=F12M16.28;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=11346655; DOI=10.1074/jbc.m103104200;
RA Sanchez-Fernandez R., Davies T.G., Coleman J.O., Rea P.A.;
RT "The Arabidopsis thaliana ABC protein superfamily, a complete inventory.";
RL J. Biol. Chem. 276:30231-30244(2001).
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=18299247; DOI=10.1016/j.tplants.2008.02.001;
RA Verrier P.J., Bird D., Burla B., Dassa E., Forestier C., Geisler M.,
RA Klein M., Kolukisaoglu H.U., Lee Y., Martinoia E., Murphy A., Rea P.A.,
RA Samuels L., Schulz B., Spalding E.J., Yazaki K., Theodoulou F.L.;
RT "Plant ABC proteins - a unified nomenclature and updated inventory.";
RL Trends Plant Sci. 13:151-159(2008).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Multi-pass membrane
CC protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCG family.
CC Eye pigment precursor importer (TC 3.A.1.204) subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAE99398.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AC008007; AAF69540.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE32936.1; -; Genomic_DNA.
DR EMBL; AK227394; BAE99398.1; ALT_INIT; mRNA.
DR RefSeq; NP_175745.4; NM_104218.5.
DR AlphaFoldDB; Q9MAG3; -.
DR SMR; Q9MAG3; -.
DR STRING; 3702.AT1G53390.1; -.
DR iPTMnet; Q9MAG3; -.
DR PaxDb; Q9MAG3; -.
DR PRIDE; Q9MAG3; -.
DR ProteomicsDB; 244635; -.
DR EnsemblPlants; AT1G53390.1; AT1G53390.1; AT1G53390.
DR GeneID; 841775; -.
DR Gramene; AT1G53390.1; AT1G53390.1; AT1G53390.
DR KEGG; ath:AT1G53390; -.
DR Araport; AT1G53390; -.
DR TAIR; locus:2009680; AT1G53390.
DR eggNOG; KOG0061; Eukaryota.
DR HOGENOM; CLU_000604_57_0_1; -.
DR InParanoid; Q9MAG3; -.
DR OMA; EIHTHSQ; -.
DR OrthoDB; 1022017at2759; -.
DR PhylomeDB; Q9MAG3; -.
DR PRO; PR:Q9MAG3; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9MAG3; baseline and differential.
DR Genevisible; Q9MAG3; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0042626; F:ATPase-coupled transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0055085; P:transmembrane transport; IBA:GO_Central.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR043926; ABCG_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF19055; ABC2_membrane_7; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 2: Evidence at transcript level;
KW ATP-binding; Membrane; Nucleotide-binding; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..1109
FT /note="ABC transporter G family member 24"
FT /id="PRO_0000240696"
FT TRANSMEM 877..897
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 904..924
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 954..974
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 986..1006
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1007..1027
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1085..1105
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 507..749
FT /note="ABC transporter"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT DOMAIN 859..1059
FT /note="ABC transmembrane type-2"
FT REGION 378..399
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 411..439
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 411..431
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 541..548
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ SEQUENCE 1109 AA; 122877 MW; 08E15D0274B568E0 CRC64;
MNFNTSLVIM LLNLKMSVDR RNWLKHGCNL RLVILVLWLV CYVSNGQTIG DTSDFNNPAV
LPLVTQMVYR SLSNSTAALN RELGIRAKFC VKDPDADWNR AFNFSSNLNF LSSCIKKTQG
SIGKRICTAA EMKFYFNGFF NKTNNPGYLK PNVNCNLTSW VSGCEPGWGC SVDPTEQVDL
QNSKDFPERR RNCMPCCEGF FCPRGLTCMI PCPLGAHCPL ATLNKTTSLC EPYTYQLPSG
RPNHTCGGAN VWADIRSSGE VFCSAGSYCP TTTQKVPCDS GHYCRMGSTS EKPCFKLTSC
NPNTANQNMH AFGIMVIAAV STILLIIYNC SDQILTTRER RQAKSREAAV KKARAHHRWK
AAREAAKKHV SGIRAQITRT FSGKRANQDG DTNKMLGRGD SSEIDEAIDM STCSSPASSS
AAQSSYENED HAAAGSNGRA SLGIEGKRVK GQTLAKIKKT QSQIFKYAYD RIEKEKAMEQ
ENKNLTFSGI VKMATNSETR KRHLMELSFK DLTLTLKSNG KQVLRCVTGS MKPGRITAVM
GPSGAGKTSL LSALAGKAVG CKLSGLILIN GKQESIHSYK KIIGFVPQDD VVHGNLTVEE
NLWFHAKCRL PADLSKADKV LVVERIIDSL GLQAVRSSLV GTVEKRGISG GQRKRVNVGL
EMVMEPSVLF LDEPTSGLDS ASSQLLLRAL RHEALEGVNI CMVVHQPSYT LFKTFNDLVL
LAKGGLTVYH GSVNKVEEYF SGLGIHVPDR INPPDYYIDV LEGVVISMGN SGIGYKELPQ
RWMLHKGYSV PLDMRNNSAA GLETNPDLGT NSPDNAEQTF ARELWRDVKS NFRLRRDKIR
HNFLKSRDLS HRRTPSTWLQ YKYFLGRIAK QRMREAQLQA TDYLILLLAG ACLGSLIKAS
DESFGAPGYI YTIIAVSLLC KIAALRSFSL DKLHYWRESA SGMSSSACFL AKDTIDIFNI
LVKPLVYLSM FYFFTNPRST FFDNYIVLVC LVYCVTGIAY ALAIFLQPST AQLFSVLLPV
VLTLVATQPK NSELIRIIAD LSYPKWALEA FVIGNAQKYY GVWMITRCGS LMKSGYDINK
WSLCIMILLL VGLTTRGVAF VGMLILQKK
