RNS13_MOUSE
ID RNS13_MOUSE Reviewed; 153 AA.
AC Q5GAM7;
DT 23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2005, sequence version 1.
DT 03-AUG-2022, entry version 99.
DE RecName: Full=Probable inactive ribonuclease-like protein 13;
DE Flags: Precursor;
GN Name=Rnase13;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=15676279; DOI=10.1016/j.ygeno.2004.10.008;
RA Cho S., Beintema J.J., Zhang J.;
RT "The ribonuclease A superfamily of mammals and birds: identifying new
RT members and tracing evolutionary histories.";
RL Genomics 85:208-220(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- FUNCTION: Does not exhibit any ribonuclease activity. {ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the pancreatic ribonuclease family.
CC {ECO:0000305}.
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DR EMBL; AY665825; AAV87192.1; -; Genomic_DNA.
DR EMBL; BC132614; AAI32615.1; -; mRNA.
DR EMBL; BC132616; AAI32617.1; -; mRNA.
DR CCDS; CCDS27048.1; -.
DR RefSeq; NP_001011687.1; NM_001011687.2.
DR RefSeq; XP_006519281.1; XM_006519218.1.
DR RefSeq; XP_006519282.1; XM_006519219.1.
DR RefSeq; XP_017171565.1; XM_017316076.1.
DR AlphaFoldDB; Q5GAM7; -.
DR SMR; Q5GAM7; -.
DR STRING; 10090.ENSMUSP00000087203; -.
DR PhosphoSitePlus; Q5GAM7; -.
DR PaxDb; Q5GAM7; -.
DR PRIDE; Q5GAM7; -.
DR ProteomicsDB; 260826; -.
DR Antibodypedia; 47225; 98 antibodies from 17 providers.
DR DNASU; 497071; -.
DR Ensembl; ENSMUST00000089771; ENSMUSP00000087203; ENSMUSG00000068392.
DR GeneID; 497071; -.
DR KEGG; mmu:497071; -.
DR UCSC; uc007tnn.2; mouse.
DR CTD; 440163; -.
DR MGI; MGI:3528592; Rnase13.
DR VEuPathDB; HostDB:ENSMUSG00000068392; -.
DR eggNOG; ENOG502SRBA; Eukaryota.
DR GeneTree; ENSGT00390000015830; -.
DR HOGENOM; CLU_1685971_0_0_1; -.
DR InParanoid; Q5GAM7; -.
DR OMA; GYCNGLM; -.
DR OrthoDB; 1461382at2759; -.
DR PhylomeDB; Q5GAM7; -.
DR TreeFam; TF343810; -.
DR BioGRID-ORCS; 497071; 4 hits in 72 CRISPR screens.
DR PRO; PR:Q5GAM7; -.
DR Proteomes; UP000000589; Chromosome 14.
DR RNAct; Q5GAM7; protein.
DR Bgee; ENSMUSG00000068392; Expressed in hindlimb stylopod muscle and 6 other tissues.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0050830; P:defense response to Gram-positive bacterium; IBA:GO_Central.
DR Gene3D; 3.10.130.10; -; 1.
DR InterPro; IPR029739; RNASE13.
DR InterPro; IPR001427; RNaseA.
DR InterPro; IPR036816; RNaseA-like_dom_sf.
DR InterPro; IPR023412; RNaseA_domain.
DR PANTHER; PTHR11437; PTHR11437; 1.
DR PANTHER; PTHR11437:SF11; PTHR11437:SF11; 1.
DR Pfam; PF00074; RnaseA; 1.
DR SMART; SM00092; RNAse_Pc; 1.
DR SUPFAM; SSF54076; SSF54076; 1.
PE 2: Evidence at transcript level;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..22
FT /evidence="ECO:0000255"
FT CHAIN 23..153
FT /note="Probable inactive ribonuclease-like protein 13"
FT /id="PRO_0000308706"
SQ SEQUENCE 153 AA; 17592 MW; AE5215027F005AC8 CRC64;
MAPDVAWLLV LPLVFRPTLV TGITIQTAIK NFRTLHVDYP MVNYPKGFHG YCNGLMAYVR
GKLQDWYCPK IHYVVHAPLE DIQKFCKYSE SFCENYNEYC TLTQNSFPVT ICTLVHQQAP
TSCSYNSTLT NQRLYLLCSR KHDAEPIGII GLY
