AB25B_ORYSJ
ID AB25B_ORYSJ Reviewed; 641 AA.
AC Q9FNU2; I0IVW0;
DT 08-MAR-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 144.
DE RecName: Full=ABC transporter B family member 25 {ECO:0000303|PubMed:18299247};
DE Short=ABC transporter ABCB.25 {ECO:0000303|PubMed:18299247};
DE Short=OsABCB25 {ECO:0000303|PubMed:18299247};
DE AltName: Full=Protein ALS1 homolog {ECO:0000305};
DE AltName: Full=Protein ALUMINUM SENSITIVE 1 {ECO:0000303|PubMed:22035218};
DE Short=OsALS1 {ECO:0000303|PubMed:22035218};
GN Name=ABCB25 {ECO:0000303|PubMed:18299247};
GN Synonyms=ALS1 {ECO:0000303|PubMed:22035218};
GN OrderedLocusNames=Os03g0755100 {ECO:0000312|EMBL:BAF13225.1},
GN LOC_Os03g54790 {ECO:0000312|EMBL:ABF98942.1};
GN ORFNames=OSJNBb0081K01.19 {ECO:0000312|EMBL:AAR01687.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=11244114; DOI=10.1104/pp.125.3.1342;
RA Dubcovsky J., Ramakrishna W., SanMiguel P.J., Busso C.S., Yan L.,
RA Shiloff B.A., Bennetzen J.L.;
RT "Comparative sequence analysis of colinear barley and rice bacterial
RT artificial chromosomes.";
RL Plant Physiol. 125:1342-1353(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, SUBCELLULAR LOCATION, TISSUE
RP SPECIFICITY, INDUCTION BY ALUMINUM, AND DISRUPTION PHENOTYPE.
RX PubMed=22035218; DOI=10.1111/j.1365-313x.2011.04837.x;
RA Huang C.F., Yamaji N., Chen Z., Ma J.F.;
RT "A tonoplast-localized half-size ABC transporter is required for internal
RT detoxification of aluminum in rice.";
RL Plant J. 69:857-867(2012).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16109971; DOI=10.1101/gr.3869505;
RG The rice chromosome 3 sequencing consortium;
RA Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B.,
RA Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T.,
RA Fadrosh D., Bera J., Weaver B., Jin S., Johri S., Reardon M., Webb K.,
RA Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T.,
RA Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R.,
RA Salzberg S.L., White O., Fraser C.M., Yu Y., Kim H., Rambo T., Currie J.,
RA Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S.S.,
RA Luo M., Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M.,
RA Pries G., Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M.,
RA Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L.,
RA O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R.,
RA Jin W., Lee H.R., Jiang J., Jackson S.;
RT "Sequence, annotation, and analysis of synteny between rice chromosome 3
RT and diverged grass species.";
RL Genome Res. 15:1284-1291(2005).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [5]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [6]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [7]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [8]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=18299247; DOI=10.1016/j.tplants.2008.02.001;
RA Verrier P.J., Bird D., Burla B., Dassa E., Forestier C., Geisler M.,
RA Klein M., Kolukisaoglu H.U., Lee Y., Martinoia E., Murphy A., Rea P.A.,
RA Samuels L., Schulz B., Spalding E.J., Yazaki K., Theodoulou F.L.;
RT "Plant ABC proteins - a unified nomenclature and updated inventory.";
RL Trends Plant Sci. 13:151-159(2008).
CC -!- FUNCTION: Metal transporter involved in the sequestration of aluminum
CC into vacuoles, which is required for cellular detoxification of
CC aluminum. {ECO:0000269|PubMed:22035218}.
CC -!- SUBCELLULAR LOCATION: Vacuole membrane {ECO:0000269|PubMed:22035218};
CC Multi-pass membrane protein {ECO:0000255}.
CC -!- TISSUE SPECIFICITY: Expressed in primary roots ans lateral roots.
CC {ECO:0000269|PubMed:22035218}.
CC -!- INDUCTION: Induced by aluminum in roots. {ECO:0000269|PubMed:22035218}.
CC -!- DISRUPTION PHENOTYPE: No visible phenotype under normal growth
CC conditions, but mutant plants are hypersensitive to aluminum.
CC {ECO:0000269|PubMed:22035218}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCB family.
CC Multidrug resistance exporter (TC 3.A.1.201) subfamily. {ECO:0000305}.
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DR EMBL; AY013245; AAG45492.1; -; Genomic_DNA.
DR EMBL; AB625451; BAM09409.1; -; mRNA.
DR EMBL; AC120509; AAR01687.1; -; Genomic_DNA.
DR EMBL; DP000009; ABF98942.1; -; Genomic_DNA.
DR EMBL; AP008209; BAF13225.1; -; Genomic_DNA.
DR EMBL; AP014959; BAS86444.1; -; Genomic_DNA.
DR EMBL; AK066049; BAG89793.1; -; mRNA.
DR AlphaFoldDB; Q9FNU2; -.
DR SMR; Q9FNU2; -.
DR STRING; 4530.OS03T0755100-01; -.
DR PaxDb; Q9FNU2; -.
DR PRIDE; Q9FNU2; -.
DR EnsemblPlants; Os03t0755100-01; Os03t0755100-01; Os03g0755100.
DR Gramene; Os03t0755100-01; Os03t0755100-01; Os03g0755100.
DR eggNOG; KOG0058; Eukaryota.
DR HOGENOM; CLU_000604_84_3_1; -.
DR InParanoid; Q9FNU2; -.
DR OMA; WGTYLVK; -.
DR PlantReactome; R-OSA-9639136; Response to Aluminum stress.
DR Proteomes; UP000000763; Chromosome 3.
DR Proteomes; UP000059680; Chromosome 3.
DR Genevisible; Q9FNU2; OS.
DR GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR GO; GO:0009705; C:plant-type vacuole membrane; IDA:UniProtKB.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0015083; F:aluminum ion transmembrane transporter activity; IDA:UniProtKB.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0042626; F:ATPase-coupled transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:1902602; P:aluminum ion transmembrane transport; IDA:UniProtKB.
DR GO; GO:0010217; P:cellular aluminum ion homeostasis; IMP:UniProtKB.
DR GO; GO:0010044; P:response to aluminum ion; IMP:UniProtKB.
DR GO; GO:0055085; P:transmembrane transport; IBA:GO_Central.
DR Gene3D; 1.20.1560.10; -; 1.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR039421; Type_1_exporter.
DR PANTHER; PTHR24221; PTHR24221; 1.
DR Pfam; PF00664; ABC_membrane; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR SUPFAM; SSF90123; SSF90123; 1.
DR PROSITE; PS50929; ABC_TM1F; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 2: Evidence at transcript level;
KW ATP-binding; Membrane; Nucleotide-binding; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport; Vacuole.
FT CHAIN 1..641
FT /note="ABC transporter B family member 25"
FT /id="PRO_0000405575"
FT TRANSMEM 52..72
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 100..120
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 191..211
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 284..304
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 320..340
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 55..346
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT DOMAIN 380..617
FT /note="ABC transporter"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT BINDING 415..422
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ SEQUENCE 641 AA; 69200 MW; F82D17EABADE0134 CRC64;
MGKNLRIKTG NRAPLLAQGE TSRALSDLEE GSNVQPENVG FCRVIKLARH DAGKLVIATM
ALLVASLSNI LVPKYGGKII DIVSRDVRRP EDKAQALDDV TGTILYIVII VVTGSVCTAL
RAWLFNSASE RVVARLRKDL FSHLVNQEIA FFDVTRTGEL LSRLSEDTQI IKNAATTNLS
EALRNITTTS IGLGFMFATS WKLTLLALVI VPVISIAVRK FGRFLRELSH QTQAAAAVAS
SIAEESFGAI RTVRSFAQES HEVLRYGEKV DETLKLGLKQ AKVVGMFSGG LNAASTLSVV
IVVIYGANLT INGYMTTGSL TSFILYSLTV GSSVSALSGL YTTVMKASGA SRRVFQLLDR
VSSMANSGDR CPTNENDGEV ELDDVWFAYP SRPSHMILKG ITLKLTPGSK VALVGPSGGG
KTTIANLIER FYDPLKGRIL LNGVPLPEIS HQFLHRKVSI VSQEPVLFNC SIEENIAYGL
EGKASSADVE NAAKMANAHN FICSFPDQYK TVVGERGIRL SGGQKQRVAI ARALLMNPRV
LLLDEATSAL DAESEYLVQD AMDSLMKGRT VLVIAHRLST VKSADTVAVI SDGQIVESGT
HDELLSRDGI YTALVKRQLQ GPRFEGTSNA TAEIEPISNG Q
