ID   RNY_ALKMQ               Reviewed;         475 AA.
AC   A6TRJ1;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   21-AUG-2007, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=Ribonuclease Y {ECO:0000255|HAMAP-Rule:MF_00335};
DE            Short=RNase Y {ECO:0000255|HAMAP-Rule:MF_00335};
DE            EC=3.1.-.- {ECO:0000255|HAMAP-Rule:MF_00335};
GN   Name=rny {ECO:0000255|HAMAP-Rule:MF_00335}; OrderedLocusNames=Amet_2657;
OS   Alkaliphilus metalliredigens (strain QYMF).
OC   Bacteria; Firmicutes; Clostridia; Eubacteriales; Clostridiaceae;
OC   Alkaliphilus.
OX   NCBI_TaxID=293826;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=QYMF;
RX   PubMed=27811105; DOI=10.1128/genomea.01226-16;
RA   Hwang C., Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina Del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Chertkov O., Brettin T., Bruce D., Han C., Schmutz J., Larimer F.,
RA   Land M.L., Hauser L., Kyrpides N., Mikhailova N., Ye Q., Zhou J.,
RA   Richardson P., Fields M.W.;
RT   "Complete genome sequence of Alkaliphilus metalliredigens strain QYMF, an
RT   alkaliphilic and metal-reducing bacterium isolated from borax-contaminated
RT   leachate ponds.";
RL   Genome Announc. 4:0-0(2016).
CC   -!- FUNCTION: Endoribonuclease that initiates mRNA decay.
CC       {ECO:0000255|HAMAP-Rule:MF_00335}.
CC   -!- SIMILARITY: Belongs to the RNase Y family. {ECO:0000255|HAMAP-
CC       Rule:MF_00335}.
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DR   EMBL; CP000724; ABR48809.1; -; Genomic_DNA.
DR   AlphaFoldDB; A6TRJ1; -.
DR   STRING; 293826.Amet_2657; -.
DR   EnsemblBacteria; ABR48809; ABR48809; Amet_2657.
DR   KEGG; amt:Amet_2657; -.
DR   eggNOG; COG1418; Bacteria.
DR   HOGENOM; CLU_028328_0_0_9; -.
DR   OMA; PHAILGM; -.
DR   Proteomes; UP000001572; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0004521; F:endoribonuclease activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006402; P:mRNA catabolic process; IEA:UniProtKB-UniRule.
DR   CDD; cd00077; HDc; 1.
DR   Gene3D; 3.30.1370.10; -; 1.
DR   HAMAP; MF_00335; RNase_Y; 1.
DR   InterPro; IPR003607; HD/PDEase_dom.
DR   InterPro; IPR006674; HD_domain.
DR   InterPro; IPR006675; HDIG_dom.
DR   InterPro; IPR004087; KH_dom.
DR   InterPro; IPR004088; KH_dom_type_1.
DR   InterPro; IPR036612; KH_dom_type_1_sf.
DR   InterPro; IPR017705; Ribonuclease_Y.
DR   InterPro; IPR022711; RNase_Y_N.
DR   PANTHER; PTHR12826:SF15; PTHR12826:SF15; 1.
DR   Pfam; PF01966; HD; 1.
DR   Pfam; PF00013; KH_1; 1.
DR   Pfam; PF12072; RNase_Y_N; 1.
DR   SMART; SM00471; HDc; 1.
DR   SMART; SM00322; KH; 1.
DR   SUPFAM; SSF54791; SSF54791; 1.
DR   TIGRFAMs; TIGR00277; HDIG; 1.
DR   TIGRFAMs; TIGR03319; RNase_Y; 1.
DR   PROSITE; PS51831; HD; 1.
DR   PROSITE; PS50084; KH_TYPE_1; 1.
PE   3: Inferred from homology;
KW   Endonuclease; Hydrolase; Nuclease; Reference proteome; RNA-binding.
FT   CHAIN           1..475
FT                   /note="Ribonuclease Y"
FT                   /id="PRO_0000344808"
FT   DOMAIN          165..228
FT                   /note="KH"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00335"
FT   DOMAIN          291..384
FT                   /note="HD"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01175"
FT   REGION          34..73
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   475 AA;  54276 MW;  974C42EEF26C5016 CRC64;
     MAKKIKDDAD KNAETTKKEV LLEAKEEIHK LRNEFERESR ERRNELQRVE RRLMQKEESL
     DKKSETLEQK DDRLSRKLRD LETKEEEIKL LYNKEVQKLE ELSGLTSQQA RELLLSDVEK
     EVKYEAAMMV KDIETKAKDD ADKKAREIIT LAIQKCAADH VAETTVTVVQ LPNDEMKGRI
     IGREGRNIRT LETLTGIDLI IDDTPEAVIL SGFDPIRREV ARIALEKLIA DGRIHPARIE
     EMVEKAKKEV ENILKEEGEQ ATFDTGVHGL HPELIRLLGR LKYRTSYGQN VLKHAIEVSH
     LAGLMATELG ADPKLAKRAG LLHDIGKAVD HEVEGTHIEI GMELLRKYKE TKDVIHAMST
     HHGDFEPETI EAILVTAADA ISAARPGARR ETLESYIKRL EKLEDIANNY DGVEKSFAIQ
     AGREIRIIVK PEVYNDDEIY MFAREITKKI EADLEYPGQI KVNVIRETRA IEYAK