ID   RNY_CAMFF               Reviewed;         517 AA.
AC   A0RNB3;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   09-JAN-2007, sequence version 1.
DT   03-AUG-2022, entry version 95.
DE   RecName: Full=Ribonuclease Y {ECO:0000255|HAMAP-Rule:MF_00335};
DE            Short=RNase Y {ECO:0000255|HAMAP-Rule:MF_00335};
DE            EC=3.1.-.- {ECO:0000255|HAMAP-Rule:MF_00335};
GN   Name=rny {ECO:0000255|HAMAP-Rule:MF_00335}; OrderedLocusNames=CFF8240_0502;
OS   Campylobacter fetus subsp. fetus (strain 82-40).
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Campylobacteraceae; Campylobacter.
OX   NCBI_TaxID=360106;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=82-40;
RA   Fouts D.E., Nelson K.E.;
RT   "Sequence of Campylobacter fetus subsp. fetus 82-40.";
RL   Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Endoribonuclease that initiates mRNA decay.
CC       {ECO:0000255|HAMAP-Rule:MF_00335}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_00335};
CC       Single-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00335}.
CC   -!- SIMILARITY: Belongs to the RNase Y family. {ECO:0000255|HAMAP-
CC       Rule:MF_00335}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000487; ABK83316.1; -; Genomic_DNA.
DR   RefSeq; WP_002848839.1; NC_008599.1.
DR   AlphaFoldDB; A0RNB3; -.
DR   SMR; A0RNB3; -.
DR   STRING; 360106.CFF8240_0502; -.
DR   PRIDE; A0RNB3; -.
DR   EnsemblBacteria; ABK83316; ABK83316; CFF8240_0502.
DR   GeneID; 61064346; -.
DR   KEGG; cff:CFF8240_0502; -.
DR   eggNOG; COG1418; Bacteria.
DR   HOGENOM; CLU_028328_1_0_7; -.
DR   OMA; PHAILGM; -.
DR   OrthoDB; 1012190at2; -.
DR   Proteomes; UP000000760; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004521; F:endoribonuclease activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006402; P:mRNA catabolic process; IEA:UniProtKB-UniRule.
DR   CDD; cd00077; HDc; 1.
DR   HAMAP; MF_00335; RNase_Y; 1.
DR   InterPro; IPR003607; HD/PDEase_dom.
DR   InterPro; IPR006674; HD_domain.
DR   InterPro; IPR006675; HDIG_dom.
DR   InterPro; IPR036612; KH_dom_type_1_sf.
DR   InterPro; IPR017705; Ribonuclease_Y.
DR   InterPro; IPR022711; RNase_Y_N.
DR   PANTHER; PTHR12826:SF15; PTHR12826:SF15; 1.
DR   Pfam; PF01966; HD; 1.
DR   Pfam; PF12072; RNase_Y_N; 1.
DR   SMART; SM00471; HDc; 1.
DR   SUPFAM; SSF54791; SSF54791; 1.
DR   TIGRFAMs; TIGR00277; HDIG; 1.
DR   TIGRFAMs; TIGR03319; RNase_Y; 1.
DR   PROSITE; PS51831; HD; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Endonuclease; Hydrolase; Membrane; Nuclease; RNA-binding;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..517
FT                   /note="Ribonuclease Y"
FT                   /id="PRO_0000344834"
FT   TRANSMEM        1..21
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00335"
FT   DOMAIN          207..273
FT                   /note="KH"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00335"
FT   DOMAIN          333..426
FT                   /note="HD"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01175"
SQ   SEQUENCE   517 AA;  57498 MW;  E18471C8B7A22C6B CRC64;
     MIEVVVGIGA GLIGIGAGYL VAKKINDANY SIFLEQAKAK AKAIEFEAES ILKDAKVKVN
     EAEFEAKKRY EEKGSRLQKE YNQKLDDISK KEHAILNEQE ILKNSKDELE KSQNQAKTLY
     EEGLNLKIAY QDKLSETLKV LEHVAGLTED EAKNMVLRKV EEKSRAEIAH IVRKYEEEAK
     KEAKKRANYI LAQATSRYAG EFAAERLINV VNIKNDELKG RIIGKEGRNI KTLEMVLGVD
     VIIDDTPHAI ILSSFNLYRR AIATRVIELL VEDGRIQPAR IEEIHKKVCD EFEASILEEG
     ENILIDLGIS KVHPEIVKLI GKLKFRASYG QNALAHSLEV AHLSGIIAAE TGGDEKLAKR
     AGILHDIGKA LTHEYEGSHV DLGAEICKRY KEHPVVINAI YAHHGHEEAL SVECAAVCAA
     DALSAARPGA RREVLESFLK RVEEIESIAI SKEGIKGAYA INAGREIRVI ANAKLVNDDE
     AVLLAKEIAE EIQDKIQYPG EIKVNVIREL RAIEFAK