ID   RNY_CHLAA               Reviewed;         510 AA.
AC   A9WJM3;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-FEB-2008, sequence version 1.
DT   03-AUG-2022, entry version 84.
DE   RecName: Full=Ribonuclease Y {ECO:0000255|HAMAP-Rule:MF_00335};
DE            Short=RNase Y {ECO:0000255|HAMAP-Rule:MF_00335};
DE            EC=3.1.-.- {ECO:0000255|HAMAP-Rule:MF_00335};
GN   Name=rny {ECO:0000255|HAMAP-Rule:MF_00335}; OrderedLocusNames=Caur_2722;
OS   Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl).
OC   Bacteria; Chloroflexi; Chloroflexia; Chloroflexales; Chloroflexineae;
OC   Chloroflexaceae; Chloroflexus.
OX   NCBI_TaxID=324602;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29366 / DSM 635 / J-10-fl;
RX   PubMed=21714912; DOI=10.1186/1471-2164-12-334;
RA   Tang K.H., Barry K., Chertkov O., Dalin E., Han C.S., Hauser L.J.,
RA   Honchak B.M., Karbach L.E., Land M.L., Lapidus A., Larimer F.W.,
RA   Mikhailova N., Pitluck S., Pierson B.K., Blankenship R.E.;
RT   "Complete genome sequence of the filamentous anoxygenic phototrophic
RT   bacterium Chloroflexus aurantiacus.";
RL   BMC Genomics 12:334-334(2011).
CC   -!- FUNCTION: Endoribonuclease that initiates mRNA decay.
CC       {ECO:0000255|HAMAP-Rule:MF_00335}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_00335};
CC       Single-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00335}.
CC   -!- SIMILARITY: Belongs to the RNase Y family. {ECO:0000255|HAMAP-
CC       Rule:MF_00335}.
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DR   EMBL; CP000909; ABY35927.1; -; Genomic_DNA.
DR   RefSeq; WP_012258580.1; NC_010175.1.
DR   RefSeq; YP_001636316.1; NC_010175.1.
DR   AlphaFoldDB; A9WJM3; -.
DR   SMR; A9WJM3; -.
DR   STRING; 324602.Caur_2722; -.
DR   PRIDE; A9WJM3; -.
DR   EnsemblBacteria; ABY35927; ABY35927; Caur_2722.
DR   KEGG; cau:Caur_2722; -.
DR   PATRIC; fig|324602.8.peg.3069; -.
DR   eggNOG; COG1418; Bacteria.
DR   HOGENOM; CLU_028328_1_0_0; -.
DR   InParanoid; A9WJM3; -.
DR   OMA; PHAILGM; -.
DR   Proteomes; UP000002008; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004521; F:endoribonuclease activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006402; P:mRNA catabolic process; IEA:UniProtKB-UniRule.
DR   CDD; cd00077; HDc; 1.
DR   Gene3D; 3.30.1370.10; -; 1.
DR   HAMAP; MF_00335; RNase_Y; 1.
DR   InterPro; IPR003607; HD/PDEase_dom.
DR   InterPro; IPR006674; HD_domain.
DR   InterPro; IPR006675; HDIG_dom.
DR   InterPro; IPR004087; KH_dom.
DR   InterPro; IPR004088; KH_dom_type_1.
DR   InterPro; IPR036612; KH_dom_type_1_sf.
DR   InterPro; IPR017705; Ribonuclease_Y.
DR   InterPro; IPR022711; RNase_Y_N.
DR   PANTHER; PTHR12826:SF15; PTHR12826:SF15; 1.
DR   Pfam; PF01966; HD; 1.
DR   Pfam; PF00013; KH_1; 1.
DR   Pfam; PF12072; RNase_Y_N; 1.
DR   SMART; SM00471; HDc; 1.
DR   SMART; SM00322; KH; 1.
DR   SUPFAM; SSF54791; SSF54791; 1.
DR   TIGRFAMs; TIGR00277; HDIG; 1.
DR   TIGRFAMs; TIGR03319; RNase_Y; 1.
DR   PROSITE; PS51831; HD; 1.
DR   PROSITE; PS50084; KH_TYPE_1; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Endonuclease; Hydrolase; Membrane; Nuclease;
KW   Reference proteome; RNA-binding; Transmembrane; Transmembrane helix.
FT   CHAIN           1..510
FT                   /note="Ribonuclease Y"
FT                   /id="PRO_0000344843"
FT   TRANSMEM        4..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00335"
FT   DOMAIN          200..260
FT                   /note="KH"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00335"
FT   DOMAIN          326..419
FT                   /note="HD"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01175"
SQ   SEQUENCE   510 AA;  57378 MW;  0ADBAA3CF99536C9 CRC64;
     MTELLWAVVA LLAGLAGGAG IGVYWANNGV SSLVQRKAAE ARLLIEEARS QQKEILLQAK
     DEALRIRNEA EAELRESRQS LQKQEERLQR KEENIDRKLE GIERRERLIQ QRERQIEQLT
     QEAERLKRQQ AQELERISQL SREEARSIIL AEVERETRED AARRIRELEQ QTKEEADKIA
     RKIIGLAIQR CASDYVAEMT VSTVNLPSEE LKGRIIGREG RNIRAFEQIT GVDIIVDDTP
     EAVTLSCHDP VRREVARVAL LKLLKDGRIH PSRIEEVVHK TQLEIEQIMR EEGERVAYEA
     NVQGLHPDLI KLLGRLKYRT SYGQNVLQHS LECALLAAHM AAELGANVNI AKTAALLHDI
     GKAVDHEVQG PHALIGAEIA RRLGRSAAIV HAIAAHHYDE EPQTVEAFLV IAADAISGAR
     PGARRETLDL YIKRLEALET VATSFPGVQR AFAVQAGREV RVMVQPDQID DLASIHLARN
     VAKKIEESLQ YPGQIKVTII RETRAVDYAR