ID   RNY_ENDTX               Reviewed;         518 AA.
AC   B1GZX3;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   29-APR-2008, sequence version 1.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=Ribonuclease Y {ECO:0000255|HAMAP-Rule:MF_00335};
DE            Short=RNase Y {ECO:0000255|HAMAP-Rule:MF_00335};
DE            EC=3.1.-.- {ECO:0000255|HAMAP-Rule:MF_00335};
GN   Name=rny {ECO:0000255|HAMAP-Rule:MF_00335}; OrderedLocusNames=TGRD_322;
OS   Endomicrobium trichonymphae.
OC   Bacteria; Elusimicrobia; Endomicrobia; Endomicrobiales; Endomicrobiaceae;
OC   Endomicrobium.
OX   NCBI_TaxID=1408204;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=18391199; DOI=10.1073/pnas.0801389105;
RA   Hongoh Y., Sharma V.K., Prakash T., Noda S., Taylor T.D., Kudo T.,
RA   Sakaki Y., Toyoda A., Hattori M., Ohkuma M.;
RT   "Complete genome of the uncultured termite group 1 bacteria in a single
RT   host protist cell.";
RL   Proc. Natl. Acad. Sci. U.S.A. 105:5555-5560(2008).
CC   -!- FUNCTION: Endoribonuclease that initiates mRNA decay.
CC       {ECO:0000255|HAMAP-Rule:MF_00335}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_00335};
CC       Single-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00335}.
CC   -!- SIMILARITY: Belongs to the RNase Y family. {ECO:0000255|HAMAP-
CC       Rule:MF_00335}.
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DR   EMBL; AP009510; BAG13805.1; -; Genomic_DNA.
DR   RefSeq; WP_015423332.1; NC_020419.1.
DR   RefSeq; YP_001956266.1; NC_020419.1.
DR   AlphaFoldDB; B1GZX3; -.
DR   SMR; B1GZX3; -.
DR   STRING; 471821.TGRD_322; -.
DR   EnsemblBacteria; BAG13805; BAG13805; TGRD_322.
DR   KEGG; rsd:TGRD_322; -.
DR   PATRIC; fig|471821.5.peg.514; -.
DR   HOGENOM; CLU_028328_1_0_0; -.
DR   OMA; PHAILGM; -.
DR   OrthoDB; 1012190at2; -.
DR   Proteomes; UP000001691; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004521; F:endoribonuclease activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006402; P:mRNA catabolic process; IEA:UniProtKB-UniRule.
DR   CDD; cd00077; HDc; 1.
DR   Gene3D; 3.30.1370.10; -; 1.
DR   HAMAP; MF_00335; RNase_Y; 1.
DR   InterPro; IPR003607; HD/PDEase_dom.
DR   InterPro; IPR006674; HD_domain.
DR   InterPro; IPR006675; HDIG_dom.
DR   InterPro; IPR004087; KH_dom.
DR   InterPro; IPR004088; KH_dom_type_1.
DR   InterPro; IPR036612; KH_dom_type_1_sf.
DR   InterPro; IPR017705; Ribonuclease_Y.
DR   InterPro; IPR022711; RNase_Y_N.
DR   PANTHER; PTHR12826:SF15; PTHR12826:SF15; 1.
DR   Pfam; PF01966; HD; 1.
DR   Pfam; PF00013; KH_1; 1.
DR   Pfam; PF12072; RNase_Y_N; 1.
DR   SMART; SM00471; HDc; 1.
DR   SMART; SM00322; KH; 1.
DR   SUPFAM; SSF54791; SSF54791; 1.
DR   TIGRFAMs; TIGR00277; HDIG; 1.
DR   TIGRFAMs; TIGR03319; RNase_Y; 1.
DR   PROSITE; PS51831; HD; 1.
DR   PROSITE; PS50084; KH_TYPE_1; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Endonuclease; Hydrolase; Membrane; Nuclease; RNA-binding;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..518
FT                   /note="Ribonuclease Y"
FT                   /id="PRO_0000344971"
FT   TRANSMEM        1..21
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00335"
FT   DOMAIN          207..270
FT                   /note="KH"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00335"
FT   DOMAIN          333..427
FT                   /note="HD"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01175"
SQ   SEQUENCE   518 AA;  58669 MW;  86B7E992855FEE0A CRC64;
     MGNITVIVIT AFVASIVGYI LRLIYAKLNI RSVEQTSKRV IEEMKLIAET KAKEIILDAR
     LIVDRERKEF EHKIKERRQF IQNMENKLNQ REESLDRKMD AVDKKEKNLS EREKDFSSKE
     HLLSVKFSEV DKVKEEQKKF LERISGMTRE EAKKILISGM EEDAKQCAAV LLQKLEQEMR
     ENADKKSKEI LSIAIQRVAA DHTADITTST IQISNDEIKG RIIGREGRNI KAFEHATGVD
     LIVDDTPESI TISAFDGIRR QIAKIALERL IADGRIHPAR IEEVVKKVKK DMEQHLKETG
     EQAVIEAGVP CSNLEIIKLL GKLKYRTSYG QSQLQHTLEV TWLAGAIAGE LGLDVMFCKK
     AALLHDIGKA VDHEVEGTHH QISANIAKKY GESHKMINAI LSHHEGFEVP SSPEAFVIAT
     ADAISAARPG ARKESVERYL KRLEKLEKVV KEFRGVSIAY AMQAGREVRI LVEPEKINDN
     QTQILAHDIA KKIEQELEYP GQIKITVVRE TRVQEIAK