ID   RNY_MESFL               Reviewed;         503 AA.
AC   Q6F1Q9;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 92.
DE   RecName: Full=Ribonuclease Y {ECO:0000255|HAMAP-Rule:MF_00335};
DE            Short=RNase Y {ECO:0000255|HAMAP-Rule:MF_00335};
DE            EC=3.1.-.- {ECO:0000255|HAMAP-Rule:MF_00335};
GN   Name=rny {ECO:0000255|HAMAP-Rule:MF_00335}; OrderedLocusNames=Mfl207;
OS   Mesoplasma florum (strain ATCC 33453 / NBRC 100688 / NCTC 11704 / L1)
OS   (Acholeplasma florum).
OC   Bacteria; Tenericutes; Mollicutes; Entomoplasmatales; Entomoplasmataceae;
OC   Mesoplasma.
OX   NCBI_TaxID=265311;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33453 / NBRC 100688 / NCTC 11704 / L1;
RA   Birren B.W., Stange-Thomann N., Hafez N., DeCaprio D., Fisher S.,
RA   Butler J., Elkins T., Kodira C.D., Major J., Wang S., Nicol R., Nusbaum C.;
RL   Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Endoribonuclease that initiates mRNA decay.
CC       {ECO:0000255|HAMAP-Rule:MF_00335}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_00335};
CC       Single-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00335}.
CC   -!- SIMILARITY: Belongs to the RNase Y family. {ECO:0000255|HAMAP-
CC       Rule:MF_00335}.
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DR   EMBL; AE017263; AAT75564.1; -; Genomic_DNA.
DR   RefSeq; WP_011183104.1; NC_006055.1.
DR   RefSeq; YP_053448.1; NC_006055.1.
DR   AlphaFoldDB; Q6F1Q9; -.
DR   SMR; Q6F1Q9; -.
DR   STRING; 265311.Mfl207; -.
DR   EnsemblBacteria; AAT75564; AAT75564; Mfl207.
DR   GeneID; 2898287; -.
DR   KEGG; mfl:Mfl207; -.
DR   PATRIC; fig|265311.5.peg.208; -.
DR   eggNOG; COG1418; Bacteria.
DR   HOGENOM; CLU_028328_1_0_14; -.
DR   OMA; PHAILGM; -.
DR   Proteomes; UP000006647; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004521; F:endoribonuclease activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006402; P:mRNA catabolic process; IEA:UniProtKB-UniRule.
DR   CDD; cd00077; HDc; 1.
DR   HAMAP; MF_00335; RNase_Y; 1.
DR   InterPro; IPR003607; HD/PDEase_dom.
DR   InterPro; IPR006674; HD_domain.
DR   InterPro; IPR006675; HDIG_dom.
DR   InterPro; IPR004087; KH_dom.
DR   InterPro; IPR004088; KH_dom_type_1.
DR   InterPro; IPR036612; KH_dom_type_1_sf.
DR   InterPro; IPR017705; Ribonuclease_Y.
DR   InterPro; IPR022711; RNase_Y_N.
DR   PANTHER; PTHR12826:SF15; PTHR12826:SF15; 1.
DR   Pfam; PF01966; HD; 1.
DR   Pfam; PF00013; KH_1; 1.
DR   Pfam; PF12072; RNase_Y_N; 1.
DR   SMART; SM00471; HDc; 1.
DR   SMART; SM00322; KH; 1.
DR   SUPFAM; SSF54791; SSF54791; 1.
DR   TIGRFAMs; TIGR00277; HDIG; 1.
DR   TIGRFAMs; TIGR03319; RNase_Y; 1.
DR   PROSITE; PS51831; HD; 1.
DR   PROSITE; PS50084; KH_TYPE_1; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Endonuclease; Hydrolase; Membrane; Nuclease;
KW   Reference proteome; RNA-binding; Transmembrane; Transmembrane helix.
FT   CHAIN           1..503
FT                   /note="Ribonuclease Y"
FT                   /id="PRO_0000344906"
FT   TRANSMEM        2..22
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00335"
FT   DOMAIN          193..253
FT                   /note="KH"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00335"
FT   DOMAIN          319..412
FT                   /note="HD"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01175"
SQ   SEQUENCE   503 AA;  56766 MW;  9B557552A59E4B63 CRC64;
     MGIIIGLIIV SVALIISLCS LLYILTSKSQ KVLNEKKIKE AKNERKKILS DTYREINEQK
     KSFEENLQFE KNKLEIAKQN IENENNLLIK ERAIIIKQQE AIDVKNTDLD KRIKNYSDKR
     EELIKRLEII SNMTSFEAKA ELMKNVESKI QYEIVSQIKQ AENLAHARAK ELSNNIILSA
     MERFKTDIVN EKTTNLVKLP NDDIKGWIIG KDGRNLKTFE QLAGVEIIVD DTPEVVTISS
     FNPIRREIAT KTLEKLLIDK RIQPIKIEKE LKVQEKLIDE TILEIGYQVM DELGIHDMDK
     ELVKLVGKLK YRTSYGQNVL LHSVEVAKIA SSIASELGLN AKQALRAGLL HDIGKAIDFE
     KTGSHVFLGV EVARKYGEDE VIINSIEAHH EDVAKESEIA VIVAIADAIS ASKPGARNNS
     IEDFIVRMKE IEKIGNSIPG ISKTYAFQAG RQIRVIVDPV TTDDKDLAGI LETLKNDLKN
     SVIIPGEITI TAIREKREIL VFN