ID   RNY_MOOTA               Reviewed;         504 AA.
AC   Q2RJJ4;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2006, sequence version 1.
DT   25-MAY-2022, entry version 88.
DE   RecName: Full=Ribonuclease Y {ECO:0000255|HAMAP-Rule:MF_00335};
DE            Short=RNase Y {ECO:0000255|HAMAP-Rule:MF_00335};
DE            EC=3.1.-.- {ECO:0000255|HAMAP-Rule:MF_00335};
GN   Name=rny {ECO:0000255|HAMAP-Rule:MF_00335}; OrderedLocusNames=Moth_1081;
OS   Moorella thermoacetica (strain ATCC 39073 / JCM 9320).
OC   Bacteria; Firmicutes; Clostridia; Thermoanaerobacterales;
OC   Thermoanaerobacteraceae; Moorella group; Moorella.
OX   NCBI_TaxID=264732;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 39073 / JCM 9320;
RX   PubMed=18631365; DOI=10.1111/j.1462-2920.2008.01679.x;
RA   Pierce E., Xie G., Barabote R.D., Saunders E., Han C.S., Detter J.C.,
RA   Richardson P., Brettin T.S., Das A., Ljungdahl L.G., Ragsdale S.W.;
RT   "The complete genome sequence of Moorella thermoacetica (f. Clostridium
RT   thermoaceticum).";
RL   Environ. Microbiol. 10:2550-2573(2008).
CC   -!- FUNCTION: Endoribonuclease that initiates mRNA decay.
CC       {ECO:0000255|HAMAP-Rule:MF_00335}.
CC   -!- SIMILARITY: Belongs to the RNase Y family. {ECO:0000255|HAMAP-
CC       Rule:MF_00335}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000232; ABC19395.1; -; Genomic_DNA.
DR   RefSeq; YP_429938.1; NC_007644.1.
DR   AlphaFoldDB; Q2RJJ4; -.
DR   SMR; Q2RJJ4; -.
DR   STRING; 264732.Moth_1081; -.
DR   EnsemblBacteria; ABC19395; ABC19395; Moth_1081.
DR   KEGG; mta:Moth_1081; -.
DR   PATRIC; fig|264732.11.peg.1162; -.
DR   eggNOG; COG1418; Bacteria.
DR   HOGENOM; CLU_028328_1_0_9; -.
DR   OMA; PHAILGM; -.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0004521; F:endoribonuclease activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006402; P:mRNA catabolic process; IEA:UniProtKB-UniRule.
DR   CDD; cd00077; HDc; 1.
DR   Gene3D; 3.30.1370.10; -; 1.
DR   HAMAP; MF_00335; RNase_Y; 1.
DR   InterPro; IPR003607; HD/PDEase_dom.
DR   InterPro; IPR006674; HD_domain.
DR   InterPro; IPR006675; HDIG_dom.
DR   InterPro; IPR004087; KH_dom.
DR   InterPro; IPR004088; KH_dom_type_1.
DR   InterPro; IPR036612; KH_dom_type_1_sf.
DR   InterPro; IPR017705; Ribonuclease_Y.
DR   InterPro; IPR022711; RNase_Y_N.
DR   PANTHER; PTHR12826:SF15; PTHR12826:SF15; 1.
DR   Pfam; PF01966; HD; 1.
DR   Pfam; PF00013; KH_1; 1.
DR   Pfam; PF12072; RNase_Y_N; 1.
DR   SMART; SM00471; HDc; 1.
DR   SMART; SM00322; KH; 1.
DR   SUPFAM; SSF54791; SSF54791; 1.
DR   TIGRFAMs; TIGR00277; HDIG; 1.
DR   TIGRFAMs; TIGR03319; RNase_Y; 1.
DR   PROSITE; PS51831; HD; 1.
DR   PROSITE; PS50084; KH_TYPE_1; 1.
PE   3: Inferred from homology;
KW   Endonuclease; Hydrolase; Nuclease; RNA-binding.
FT   CHAIN           1..504
FT                   /note="Ribonuclease Y"
FT                   /id="PRO_0000344907"
FT   DOMAIN          194..279
FT                   /note="KH"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00335"
FT   DOMAIN          320..413
FT                   /note="HD"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01175"
SQ   SEQUENCE   504 AA;  56778 MW;  5FC8B0ED9DD23C1E CRC64;
     MLIAFLVGGA GGYAIRKYLA EAKIASAEKA AATIIEEAKK EAEARKREAV LEAKDEVHRM
     RNEVERESRE RRNELQRLER RLLQKEETLE RKSETLERKE ASLHRQEEAI QRTREEVEKI
     RQQQVSELER ISGLTTEAAR NILLKNVEEE IRHETAMLIK QVEAEAKEEA EKRAREIITY
     AIQHCAADYV AEATVSVVNL PNDEMKGRII GREGRNIRAL ETLTGVDLII DDTPEAVILS
     CFDPIRREIA RIALEKLIAD GRIHPARIEE MVEKARRELD TKIREEGEQA TFEVGIHGLH
     PELVRLLGKL KYRTSYGQNV LKHSLEVAFL AGAMAAELGV DVLVAKRAGL LHDIGKAVDF
     EVEGPHVNLG VELAKKYRES PEVIHAIEAH HGDVEPKSIE AGLVQAADAI SAARPGARRE
     TLEAYIKRLE KLEEIANSFS GVEKSYAIQA GREVRILVKP DKIDDAMAVR LARDIVKTIE
     QTMEYPGQIK VVVIRETRAV DYAK