ID   RNY_MYCCT               Reviewed;         509 AA.
AC   Q2SRU2;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2006, sequence version 1.
DT   25-MAY-2022, entry version 98.
DE   RecName: Full=Ribonuclease Y {ECO:0000255|HAMAP-Rule:MF_00335};
DE            Short=RNase Y {ECO:0000255|HAMAP-Rule:MF_00335};
DE            EC=3.1.-.- {ECO:0000255|HAMAP-Rule:MF_00335};
GN   Name=rny {ECO:0000255|HAMAP-Rule:MF_00335}; OrderedLocusNames=MCAP_0550;
OS   Mycoplasma capricolum subsp. capricolum (strain California kid / ATCC 27343
OS   / NCTC 10154).
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX   NCBI_TaxID=340047;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=California kid / ATCC 27343 / NCTC 10154;
RA   Glass J.I., Lartigue C., Pfannkoch C., Baden-Tillson H., Smith H.O.,
RA   Venter J.C., Roske K., Wise K.S., Calcutt M.J., Nelson W.C., Nierman W.C.;
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Endoribonuclease that initiates mRNA decay.
CC       {ECO:0000255|HAMAP-Rule:MF_00335}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_00335};
CC       Single-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00335}.
CC   -!- SIMILARITY: Belongs to the RNase Y family. {ECO:0000255|HAMAP-
CC       Rule:MF_00335}.
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DR   EMBL; CP000123; ABC01599.1; -; Genomic_DNA.
DR   RefSeq; WP_011387419.1; NC_007633.1.
DR   AlphaFoldDB; Q2SRU2; -.
DR   SMR; Q2SRU2; -.
DR   EnsemblBacteria; ABC01599; ABC01599; MCAP_0550.
DR   GeneID; 23778493; -.
DR   KEGG; mcp:MCAP_0550; -.
DR   HOGENOM; CLU_028328_1_0_14; -.
DR   OMA; PHAILGM; -.
DR   OrthoDB; 1012190at2; -.
DR   PhylomeDB; Q2SRU2; -.
DR   Proteomes; UP000001928; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004521; F:endoribonuclease activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006402; P:mRNA catabolic process; IEA:UniProtKB-UniRule.
DR   CDD; cd00077; HDc; 1.
DR   HAMAP; MF_00335; RNase_Y; 1.
DR   InterPro; IPR003607; HD/PDEase_dom.
DR   InterPro; IPR006674; HD_domain.
DR   InterPro; IPR006675; HDIG_dom.
DR   InterPro; IPR004087; KH_dom.
DR   InterPro; IPR004088; KH_dom_type_1.
DR   InterPro; IPR036612; KH_dom_type_1_sf.
DR   InterPro; IPR017705; Ribonuclease_Y.
DR   InterPro; IPR022711; RNase_Y_N.
DR   PANTHER; PTHR12826:SF15; PTHR12826:SF15; 1.
DR   Pfam; PF01966; HD; 1.
DR   Pfam; PF00013; KH_1; 1.
DR   Pfam; PF12072; RNase_Y_N; 1.
DR   SMART; SM00471; HDc; 1.
DR   SMART; SM00322; KH; 1.
DR   SUPFAM; SSF54791; SSF54791; 1.
DR   TIGRFAMs; TIGR00277; HDIG; 1.
DR   TIGRFAMs; TIGR03319; RNase_Y; 1.
DR   PROSITE; PS51831; HD; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Endonuclease; Hydrolase; Membrane; Nuclease; RNA-binding;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..509
FT                   /note="Ribonuclease Y"
FT                   /id="PRO_0000344908"
FT   TRANSMEM        5..25
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00335"
FT   DOMAIN          199..259
FT                   /note="KH"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00335"
FT   DOMAIN          325..418
FT                   /note="HD"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01175"
SQ   SEQUENCE   509 AA;  57509 MW;  350FB08DD5D49010 CRC64;
     MNDDIIILLS VFCGIFFICF IICSSIALYL WKSKSRKRLV EQYTKEAKQA KKQILANGYK
     EISEAKMLFL KRSELEKNEL DRVKEQLELR SNDLKRNQEI VESKSQRLDA SLLDLEKRKF
     LLDKKEEYLI KVLEDASSLT KSQAKELLIK QVKNKSEKEL ISILKNAELQ AHSNSKMIAN
     NIIISAMERI KVELTSQRTT NIVKLPSDDL KGRIIGKDGR NMKAFKQIGG VDIVIDETPN
     TVVVSSFNPI RREIATRTLE QLIIDGRIQP VKIENELKKQ EQELEYIIQE TGLSTIKELN
     INDIDIELVK LIGKLKFRTS YGQNVLAHSI EVAKLSGAIA SELGLDVEKA IRAGLLHDIG
     KAIDFEKQGS HVVLGAEIAK KYNEDPIVIN CIESHHEDKE KESEIAAIVA IADSISASRP
     GARYNAIDEF ILRMTEIEKI GNSIPGVAKT YALQSGRQIR LIVDPLVASD LDLAMILEKM
     KEEIKNKVII PGEITITVIR ERKETDVLK