RNY_MYCGA
ID RNY_MYCGA Reviewed; 593 AA.
AC Q7NB09;
DT 22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT 15-JUN-2010, sequence version 2.
DT 03-AUG-2022, entry version 110.
DE RecName: Full=Ribonuclease Y {ECO:0000255|HAMAP-Rule:MF_00335};
DE Short=RNase Y {ECO:0000255|HAMAP-Rule:MF_00335};
DE EC=3.1.-.- {ECO:0000255|HAMAP-Rule:MF_00335};
GN Name=rny {ECO:0000255|HAMAP-Rule:MF_00335}; OrderedLocusNames=MYCGA4710;
GN ORFNames=MGA_0141;
OS Mycoplasma gallisepticum (strain R(low / passage 15 / clone 2))
OS (Mycoplasmoides gallisepticum).
OC Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX NCBI_TaxID=710127;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R(low / passage 15 / clone 2);
RX PubMed=12949158; DOI=10.1099/mic.0.26427-0;
RA Papazisi L., Gorton T.S., Kutish G., Markham P.F., Browning G.F.,
RA Nguyen D.K., Swartzell S., Madan A., Mahairas G., Geary S.J.;
RT "The complete genome sequence of the avian pathogen Mycoplasma
RT gallisepticum strain R(low).";
RL Microbiology 149:2307-2316(2003).
CC -!- FUNCTION: Endoribonuclease that initiates mRNA decay.
CC {ECO:0000255|HAMAP-Rule:MF_00335}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_00335};
CC Single-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00335}.
CC -!- SIMILARITY: Belongs to the RNase Y family. {ECO:0000255|HAMAP-
CC Rule:MF_00335}.
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DR EMBL; AE015450; AAP56821.2; -; Genomic_DNA.
DR RefSeq; WP_011113720.1; NC_004829.2.
DR AlphaFoldDB; Q7NB09; -.
DR SMR; Q7NB09; -.
DR PRIDE; Q7NB09; -.
DR KEGG; mga:MGA_0141; -.
DR PATRIC; fig|233150.7.peg.529; -.
DR HOGENOM; CLU_459917_0_0_14; -.
DR OrthoDB; 1012190at2; -.
DR Proteomes; UP000001418; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004521; F:endoribonuclease activity; IEA:UniProtKB-UniRule.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006402; P:mRNA catabolic process; IEA:UniProtKB-UniRule.
DR CDD; cd00077; HDc; 1.
DR HAMAP; MF_00335; RNase_Y; 1.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR006675; HDIG_dom.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR InterPro; IPR017705; Ribonuclease_Y.
DR PANTHER; PTHR12826:SF15; PTHR12826:SF15; 1.
DR Pfam; PF01966; HD; 1.
DR SMART; SM00471; HDc; 1.
DR SMART; SM00322; KH; 1.
DR SUPFAM; SSF54791; SSF54791; 1.
DR TIGRFAMs; TIGR00277; HDIG; 1.
DR PROSITE; PS51831; HD; 1.
PE 3: Inferred from homology;
KW Cell membrane; Endonuclease; Hydrolase; Membrane; Nuclease;
KW Reference proteome; RNA-binding; Transmembrane; Transmembrane helix.
FT CHAIN 1..593
FT /note="Ribonuclease Y"
FT /id="PRO_0000344909"
FT TRANSMEM 6..26
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00335"
FT DOMAIN 218..278
FT /note="KH"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00335"
FT DOMAIN 354..464
FT /note="HD"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01175"
SQ SEQUENCE 593 AA; 68706 MW; 07792B935A8C2A35 CRC64;
MITISILLMY LIVGLLTALT VLIFVFILLK FYEFRFFKQT ETYQRELEQE ILKINNQEEL
EEKLKEHYLF QSNHKVFTKR DLREIRNFFI AVLSDKILLE NKNKLLSNEI IEKKKENEEL
KTKLDAKKVE EKITLLKEMN LTHEEAKKRL LEEYRGYVRN DLDKMVKEEE KAANDKKNAI
TNELNKLLIN AMGNVSLLTE TVRMNTVKTI KYEYVDVDPI KVKKVTDDFF GKIIGKEARN
KKYIERLFNV EIIIKPESSR ISISSFNTIK LEVAYNALNK IIEAVNDQGT HVLDESLIRK
SWYGALNEFS AEAKRIGEET LKELGLYESA FIPTKEISEF IGRLKFRGSN TQNVLTHSIE
AAQIAESIAD QLNLNKEKAK VCALLHDIGK AIDKESVSSE GKWKNLKYAA NDHVSAGVEI
AQYYKFDIDI IDAINCHHGR KKIYEKSKNF YAKITKIADF LSAARPGVRF VKDNDIERRF
DTISNILTKY VDEKIISTYK ILKNGYNINL MINPDITESE YSQLTLDLKK DIESDKELSK
YPITITYVQN ITRSETTNAI AHAKKTVEIY SEDKAELVND EELSTVEFLD EDI
