ID   RNY_MYCMY               Reviewed;         422 AA.
AC   Q01444;
DT   01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1993, sequence version 1.
DT   25-MAY-2022, entry version 84.
DE   RecName: Full=Ribonuclease Y {ECO:0000255|HAMAP-Rule:MF_00335};
DE            Short=RNase Y {ECO:0000255|HAMAP-Rule:MF_00335};
DE            EC=3.1.-.- {ECO:0000255|HAMAP-Rule:MF_00335};
DE   Flags: Fragment;
GN   Name=rny {ECO:0000255|HAMAP-Rule:MF_00335};
OS   Mycoplasma mycoides.
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX   NCBI_TaxID=2102;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1280809; DOI=10.1093/nar/20.21.5763;
RA   Samuelsson T.B.;
RT   "A Mycoplasma protein homologous to mammalian SRP54 recognizes a highly
RT   conserved domain of SRP RNA.";
RL   Nucleic Acids Res. 20:5763-5770(1992).
CC   -!- FUNCTION: Endoribonuclease that initiates mRNA decay.
CC       {ECO:0000255|HAMAP-Rule:MF_00335}.
CC   -!- SIMILARITY: Belongs to the RNase Y family. {ECO:0000255|HAMAP-
CC       Rule:MF_00335}.
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DR   EMBL; M91593; AAA25440.1; -; Genomic_DNA.
DR   PIR; S35480; S35480.
DR   AlphaFoldDB; Q01444; -.
DR   SMR; Q01444; -.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006402; P:mRNA catabolic process; IEA:InterPro.
DR   CDD; cd00077; HDc; 1.
DR   Gene3D; 3.30.1370.10; -; 1.
DR   HAMAP; MF_00335; RNase_Y; 1.
DR   InterPro; IPR003607; HD/PDEase_dom.
DR   InterPro; IPR006674; HD_domain.
DR   InterPro; IPR006675; HDIG_dom.
DR   InterPro; IPR004087; KH_dom.
DR   InterPro; IPR004088; KH_dom_type_1.
DR   InterPro; IPR036612; KH_dom_type_1_sf.
DR   InterPro; IPR017705; Ribonuclease_Y.
DR   InterPro; IPR022711; RNase_Y_N.
DR   PANTHER; PTHR12826:SF15; PTHR12826:SF15; 1.
DR   Pfam; PF01966; HD; 1.
DR   Pfam; PF00013; KH_1; 1.
DR   Pfam; PF12072; RNase_Y_N; 1.
DR   SMART; SM00471; HDc; 1.
DR   SMART; SM00322; KH; 1.
DR   SUPFAM; SSF54791; SSF54791; 1.
DR   TIGRFAMs; TIGR00277; HDIG; 1.
DR   TIGRFAMs; TIGR03319; RNase_Y; 1.
DR   PROSITE; PS51831; HD; 1.
PE   3: Inferred from homology;
KW   Endonuclease; Hydrolase; Nuclease; RNA-binding.
FT   CHAIN           <1..422
FT                   /note="Ribonuclease Y"
FT                   /id="PRO_0000163781"
FT   DOMAIN          112..172
FT                   /note="KH"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00335"
FT   DOMAIN          238..331
FT                   /note="HD"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01175"
FT   NON_TER         1
SQ   SEQUENCE   422 AA;  47328 MW;  D64F4FAD873C0969 CRC64;
     DLRANDLKRS QEIVESKSQR LDAGILDLEK RKFLVDQKEE YLIKLLEDVS GLTKYQAKEL
     LIKQIKNKSE KELISILKNA ELQAHSKAKI ISNNILILAM ERIKVELTSQ RTTNIVKLPS
     DDLKGRIIGK DGRNMKTFEQ IGGVDIVVDE TPNVVVVSSF NPIRREIATR TLEQLIIDGR
     IQPVKIENEL KKQEQELEYI IQETGLNTIK ELNINDIDIE LVKLIGKLKF RTSYGQNVLA
     HSIEVAKLSG AIASELGLDV EKAIRAGLLH DIGKAIDFEK QGSHVVLGAE IARKYNEDPI
     IINSIESHHE DKEKSSEIAA IVAIADSISA SRPGARYNAI DEFILRMHEI EKIGNSIPGV
     AKTYALQSGR QIRLIVDPLV ASDLDLALIL EKMKEQIKNK VIIPGEITIT VIREKKETDI
     LK