ID   RNY_SALAI               Reviewed;         588 AA.
AC   A8M7V7;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   04-DEC-2007, sequence version 1.
DT   25-MAY-2022, entry version 87.
DE   RecName: Full=Ribonuclease Y {ECO:0000255|HAMAP-Rule:MF_00335};
DE            Short=RNase Y {ECO:0000255|HAMAP-Rule:MF_00335};
DE            EC=3.1.-.- {ECO:0000255|HAMAP-Rule:MF_00335};
GN   Name=rny {ECO:0000255|HAMAP-Rule:MF_00335}; OrderedLocusNames=Sare_1391;
OS   Salinispora arenicola (strain CNS-205).
OC   Bacteria; Actinobacteria; Micromonosporales; Micromonosporaceae;
OC   Salinispora.
OX   NCBI_TaxID=391037;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CNS-205;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA   Tice H., Pitluck S., Foster B., Schmutz J., Larimer F., Land M., Hauser L.,
RA   Kyrpides N., Ivanova N., Jensen P.R., Moore B.S., Penn K., Jenkins C.,
RA   Udwary D., Xiang L., Gontang E., Richardson P.;
RT   "Complete sequence of Salinispora arenicola CNS-205.";
RL   Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Endoribonuclease that initiates mRNA decay.
CC       {ECO:0000255|HAMAP-Rule:MF_00335}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_00335};
CC       Single-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00335}.
CC   -!- SIMILARITY: Belongs to the RNase Y family. {ECO:0000255|HAMAP-
CC       Rule:MF_00335}.
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DR   EMBL; CP000850; ABV97291.1; -; Genomic_DNA.
DR   RefSeq; WP_012181599.1; NC_009953.1.
DR   AlphaFoldDB; A8M7V7; -.
DR   SMR; A8M7V7; -.
DR   STRING; 391037.Sare_1391; -.
DR   EnsemblBacteria; ABV97291; ABV97291; Sare_1391.
DR   GeneID; 5703750; -.
DR   KEGG; saq:Sare_1391; -.
DR   PATRIC; fig|391037.6.peg.1416; -.
DR   eggNOG; COG1418; Bacteria.
DR   HOGENOM; CLU_028328_1_0_11; -.
DR   OMA; PHAILGM; -.
DR   OrthoDB; 1012190at2; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004521; F:endoribonuclease activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006402; P:mRNA catabolic process; IEA:UniProtKB-UniRule.
DR   CDD; cd00077; HDc; 1.
DR   HAMAP; MF_00335; RNase_Y; 1.
DR   InterPro; IPR003607; HD/PDEase_dom.
DR   InterPro; IPR006674; HD_domain.
DR   InterPro; IPR006675; HDIG_dom.
DR   InterPro; IPR004088; KH_dom_type_1.
DR   InterPro; IPR036612; KH_dom_type_1_sf.
DR   InterPro; IPR017705; Ribonuclease_Y.
DR   InterPro; IPR022711; RNase_Y_N.
DR   PANTHER; PTHR12826:SF15; PTHR12826:SF15; 1.
DR   Pfam; PF01966; HD; 1.
DR   Pfam; PF00013; KH_1; 1.
DR   Pfam; PF12072; RNase_Y_N; 1.
DR   SMART; SM00471; HDc; 1.
DR   SUPFAM; SSF54791; SSF54791; 1.
DR   TIGRFAMs; TIGR00277; HDIG; 1.
DR   TIGRFAMs; TIGR03319; RNase_Y; 1.
DR   PROSITE; PS51831; HD; 1.
DR   PROSITE; PS50084; KH_TYPE_1; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Endonuclease; Hydrolase; Membrane; Nuclease; RNA-binding;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..588
FT                   /note="Ribonuclease Y"
FT                   /id="PRO_0000344930"
FT   TRANSMEM        7..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00335"
FT   DOMAIN          278..359
FT                   /note="KH"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00335"
FT   DOMAIN          404..497
FT                   /note="HD"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01175"
FT   REGION          130..162
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        148..162
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   588 AA;  64289 MW;  2A34A8D7944955AB CRC64;
     MSGFDAVLLV AVLLLALIVL GAVLVGVRAV RGIAGAPRPE DPAFIAEKDR QEQSLAALRS
     AADEANSTVD AAKSAAAAAR TEAAAARAEA KAARAEARRV LDGARAEADT ILERVHKQAE
     ADAEQLRTAA RRSGEREAAV LATTTREQAA EVERRAARMD DRERLHSEEV ERLAERDRQL
     SAASAALAAR ESTLVDRDRE LAQAEDRRRR ELERVAGITA EAARGELVEA IEAQAKREAA
     LLVREIESEA RNTGEERARH IVVDAIQRVA SEQTAESVVS VLHLPGDEMK GRIIGREGRN
     IRAFESVTGV NLIIDDTPEA VLLSCFDPVR REVGRLTLEK LVLDGRIHPH RIEEVHDLAR
     QEVVQLCQRA AEDALVEVGI TEIHPELVSL LGRLRYRTSY GQNVLKHLVE TAHIAGIMAA
     ELRLDVPTIK RCAFLHDIGK ALTHEVEGSH AIVGADVARK YGESEDVVHA IEAHHNEVPP
     QTIEAVLTQA SDACSGGRPG ARRESLEAYV RRLERIEEIA AGKLGVERVF AMQAGREVRV
     MVRPEDVDDI SASVLARDVA KQIEEELTYP GQIRVTVVRE SRVTEIAR