ID   RNY_UREP2               Reviewed;         473 AA.
AC   B1AI70;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   08-APR-2008, sequence version 1.
DT   03-AUG-2022, entry version 80.
DE   RecName: Full=Ribonuclease Y {ECO:0000255|HAMAP-Rule:MF_00335};
DE            Short=RNase Y {ECO:0000255|HAMAP-Rule:MF_00335};
DE            EC=3.1.-.- {ECO:0000255|HAMAP-Rule:MF_00335};
GN   Name=rny {ECO:0000255|HAMAP-Rule:MF_00335}; OrderedLocusNames=UPA3_0084;
OS   Ureaplasma parvum serovar 3 (strain ATCC 27815 / 27 / NCTC 11736).
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Ureaplasma.
OX   NCBI_TaxID=505682;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27815 / 27 / NCTC 11736;
RA   Methe B.A., Glass J., Waites K., Shrivastava S.;
RT   "Genome sequence of Ureaplasma parvum serovar 3.";
RL   Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Endoribonuclease that initiates mRNA decay.
CC       {ECO:0000255|HAMAP-Rule:MF_00335}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_00335};
CC       Single-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00335}.
CC   -!- SIMILARITY: Belongs to the RNase Y family. {ECO:0000255|HAMAP-
CC       Rule:MF_00335}.
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DR   EMBL; CP000942; ACA32756.1; -; Genomic_DNA.
DR   RefSeq; WP_006688749.1; NC_010503.1.
DR   AlphaFoldDB; B1AI70; -.
DR   SMR; B1AI70; -.
DR   PRIDE; B1AI70; -.
DR   EnsemblBacteria; ACA32756; ACA32756; UPA3_0084.
DR   GeneID; 29672747; -.
DR   KEGG; upa:UPA3_0084; -.
DR   HOGENOM; CLU_028328_1_0_14; -.
DR   OMA; PHAILGM; -.
DR   OrthoDB; 1012190at2; -.
DR   Proteomes; UP000002162; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004521; F:endoribonuclease activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006402; P:mRNA catabolic process; IEA:UniProtKB-UniRule.
DR   CDD; cd00077; HDc; 1.
DR   HAMAP; MF_00335; RNase_Y; 1.
DR   InterPro; IPR003607; HD/PDEase_dom.
DR   InterPro; IPR006674; HD_domain.
DR   InterPro; IPR006675; HDIG_dom.
DR   InterPro; IPR036612; KH_dom_type_1_sf.
DR   InterPro; IPR017705; Ribonuclease_Y.
DR   PANTHER; PTHR12826:SF15; PTHR12826:SF15; 1.
DR   Pfam; PF01966; HD; 1.
DR   SMART; SM00471; HDc; 1.
DR   SUPFAM; SSF54791; SSF54791; 1.
DR   TIGRFAMs; TIGR00277; HDIG; 1.
DR   PROSITE; PS51831; HD; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Endonuclease; Hydrolase; Membrane; Nuclease; RNA-binding;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..473
FT                   /note="Ribonuclease Y"
FT                   /id="PRO_0000344972"
FT   TRANSMEM        4..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00335"
FT   DOMAIN          158..218
FT                   /note="KH"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00335"
FT   DOMAIN          285..378
FT                   /note="HD"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01175"
SQ   SEQUENCE   473 AA;  54323 MW;  D02D83602817F112 CRC64;
     MGYLIAFIIL LILFVLLITI VPVVMVVYLK KKQLKLTFVP KSQTSFKKIV QKTKDLEEEC
     EDLNNKNNEL KKAISDQNLQ IDLLKKNNEN FLLNATSLTA EQAKKELFNL LKIKFKKELA
     QEYAKIKHEF NEAQEIYAQN ILVETMEQIA EPLIVERSLF NIDIIDENLK GKIIGRDGRN
     KAVFENEGGV DLIVDRQQPI VGISTPNPIR REIARIVMQK LIDSKNIDIN RIELLFKEER
     EKFEKKVFEI GKNVVEQTLG FFDLPEGIYS YIGRMKFRNS YGQNILSHSL EVAEYAERIA
     KLINIDPIKA KKAAFFHDIG KTIDFESDLD HVEAGLLIAK KFNLDDYIYN AIESHHNKVI
     PTTIYGALVK IVDTLSAARP GARVNSYDEY YSRVKELETI CMRFEGVKSA YVIKSGRQLR
     VIVDSNLVSD EQLELLGHEI KVAIEENDLL TNYKIKIVLI KEKRISIDTN IIG