ID   RNY_WOLSU               Reviewed;         523 AA.
AC   Q7MAR9;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   22-JUL-2008, sequence version 2.
DT   25-MAY-2022, entry version 106.
DE   RecName: Full=Ribonuclease Y {ECO:0000255|HAMAP-Rule:MF_00335};
DE            Short=RNase Y {ECO:0000255|HAMAP-Rule:MF_00335};
DE            EC=3.1.-.- {ECO:0000255|HAMAP-Rule:MF_00335};
GN   Name=rny {ECO:0000255|HAMAP-Rule:MF_00335}; OrderedLocusNames=WS0071;
OS   Wolinella succinogenes (strain ATCC 29543 / DSM 1740 / LMG 7466 / NCTC
OS   11488 / FDC 602W) (Vibrio succinogenes).
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Wolinella.
OX   NCBI_TaxID=273121;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29543 / DSM 1740 / CCUG 13145 / JCM 31913 / LMG 7466 / NCTC
RC   11488 / FDC 602W;
RX   PubMed=14500908; DOI=10.1073/pnas.1932838100;
RA   Baar C., Eppinger M., Raddatz G., Simon J., Lanz C., Klimmek O.,
RA   Nandakumar R., Gross R., Rosinus A., Keller H., Jagtap P., Linke B.,
RA   Meyer F., Lederer H., Schuster S.C.;
RT   "Complete genome sequence and analysis of Wolinella succinogenes.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:11690-11695(2003).
CC   -!- FUNCTION: Endoribonuclease that initiates mRNA decay.
CC       {ECO:0000255|HAMAP-Rule:MF_00335}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_00335};
CC       Single-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00335}.
CC   -!- SIMILARITY: Belongs to the RNase Y family. {ECO:0000255|HAMAP-
CC       Rule:MF_00335}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAE09240.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; BX571657; CAE09240.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_041571662.1; NC_005090.1.
DR   AlphaFoldDB; Q7MAR9; -.
DR   SMR; Q7MAR9; -.
DR   STRING; 273121.WS0071; -.
DR   EnsemblBacteria; CAE09240; CAE09240; WS0071.
DR   KEGG; wsu:WS0071; -.
DR   eggNOG; COG1418; Bacteria.
DR   HOGENOM; CLU_028328_1_0_7; -.
DR   OrthoDB; 1012190at2; -.
DR   Proteomes; UP000000422; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004521; F:endoribonuclease activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006402; P:mRNA catabolic process; IEA:UniProtKB-UniRule.
DR   CDD; cd00077; HDc; 1.
DR   Gene3D; 3.30.1370.10; -; 1.
DR   HAMAP; MF_00335; RNase_Y; 1.
DR   InterPro; IPR003607; HD/PDEase_dom.
DR   InterPro; IPR006674; HD_domain.
DR   InterPro; IPR006675; HDIG_dom.
DR   InterPro; IPR004087; KH_dom.
DR   InterPro; IPR004088; KH_dom_type_1.
DR   InterPro; IPR036612; KH_dom_type_1_sf.
DR   InterPro; IPR017705; Ribonuclease_Y.
DR   InterPro; IPR022711; RNase_Y_N.
DR   PANTHER; PTHR12826:SF15; PTHR12826:SF15; 1.
DR   Pfam; PF01966; HD; 1.
DR   Pfam; PF00013; KH_1; 1.
DR   Pfam; PF12072; RNase_Y_N; 1.
DR   SMART; SM00471; HDc; 1.
DR   SMART; SM00322; KH; 1.
DR   SUPFAM; SSF54791; SSF54791; 1.
DR   TIGRFAMs; TIGR00277; HDIG; 1.
DR   TIGRFAMs; TIGR03319; RNase_Y; 1.
DR   PROSITE; PS51831; HD; 1.
DR   PROSITE; PS50084; KH_TYPE_1; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Endonuclease; Hydrolase; Membrane; Nuclease;
KW   Reference proteome; RNA-binding; Transmembrane; Transmembrane helix.
FT   CHAIN           1..523
FT                   /note="Ribonuclease Y"
FT                   /id="PRO_0000344973"
FT   TRANSMEM        7..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00335"
FT   DOMAIN          213..279
FT                   /note="KH"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00335"
FT   DOMAIN          339..432
FT                   /note="HD"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01175"
SQ   SEQUENCE   523 AA;  58368 MW;  E2548C4ACFD20B70 CRC64;
     MIEWTILSSL ASALLAGGGT YLVYKKVSNA NYKIHLEKAK ARARAIEHEA EMILQEAKIR
     AKELEIGAKS KYENETSKVI KEYESYLIKL EKQEAKNQQR LERETQQLEE ERRRINHKQA
     SLSGMIEELE KLKGDYRSKL TESLEILSRV AGLTQEEAKE LALAKATEES RAQIAQIVRK
     YESEAKEEGR KRANYILAQA TTRFAGEFAA ERLINVVNLP NDELKGRIIG KEGRNIKTLE
     MLSGVDVIID DTPGAIVLSS FNLYRRAIAT RTIEALVEDG RIQPARIEEV YKKVEQEFEE
     KVLEEGEGIV LDMELGYVHP ELKKLIGRLK YRASYGQNAL GHSLEVANLA GVIAGELGGD
     VKLAKRAGLL HDIGKALTHD FGGSHVDLGA EVCSRYKEHP VVINAIFAHH GHEEAKSIES
     AAVCAADALS AARPGARREV LESFLKRVQE IEKIAMEKLG VRQAYAINAG REVRVIVNAD
     LINDEESVLL AQEIAKEIET KVQYPGEIKV SVIREVRAVE FAK