ID   AB26B_ARATH             Reviewed;         700 AA.
AC   Q8RY46; Q9CAB3; Q9CAL0;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   03-AUG-2022, entry version 140.
DE   RecName: Full=ABC transporter B family member 26, chloroplastic;
DE            Short=ABC transporter ABCB.26;
DE            Short=AtABCB26;
DE   AltName: Full=Antigen peptide transporter-like 1;
DE   AltName: Full=Transporter associated with antigen processing-like protein 1;
DE            Short=AtTAP1;
DE   Flags: Precursor;
GN   Name=ABCB26; Synonyms=TAP1; OrderedLocusNames=At1g70610;
GN   ORFNames=F24J13.18, F5A18.21;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=11346655; DOI=10.1074/jbc.m103104200;
RA   Sanchez-Fernandez R., Davies T.G., Coleman J.O., Rea P.A.;
RT   "The Arabidopsis thaliana ABC protein superfamily, a complete inventory.";
RL   J. Biol. Chem. 276:30231-30244(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130712; DOI=10.1038/35048500;
RA   Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA   Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA   Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA   Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA   Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA   Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA   Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA   Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA   Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA   Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA   Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA   Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA   Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA   Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA   Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT   "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL   Nature 408:816-820(2000).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RA   Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA   Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA   Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA   Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA   Shinozaki K.;
RT   "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL   Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN   [5]
RP   IDENTIFICATION BY MASS SPECTROMETRY, AND SUBCELLULAR LOCATION [LARGE SCALE
RP   ANALYSIS].
RX   PubMed=18431481; DOI=10.1371/journal.pone.0001994;
RA   Zybailov B., Rutschow H., Friso G., Rudella A., Emanuelsson O., Sun Q.,
RA   van Wijk K.J.;
RT   "Sorting signals, N-terminal modifications and abundance of the chloroplast
RT   proteome.";
RL   PLoS ONE 3:E1994-E1994(2008).
RN   [6]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=18299247; DOI=10.1016/j.tplants.2008.02.001;
RA   Verrier P.J., Bird D., Burla B., Dassa E., Forestier C., Geisler M.,
RA   Klein M., Kolukisaoglu H.U., Lee Y., Martinoia E., Murphy A., Rea P.A.,
RA   Samuels L., Schulz B., Spalding E.J., Yazaki K., Theodoulou F.L.;
RT   "Plant ABC proteins - a unified nomenclature and updated inventory.";
RL   Trends Plant Sci. 13:151-159(2008).
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast membrane
CC       {ECO:0000269|PubMed:18431481}; Multi-pass membrane protein
CC       {ECO:0000255|PROSITE-ProRule:PRU00441, ECO:0000269|PubMed:18431481}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCB family.
CC       Multidrug resistance exporter (TC 3.A.1.201) subfamily. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAG52334.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC       Sequence=AAG52466.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AY078409; AAL85485.1; -; mRNA.
DR   EMBL; AC010796; AAG52466.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AC011663; AAG52334.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002684; AEE35088.1; -; Genomic_DNA.
DR   EMBL; AK228750; BAF00650.1; -; mRNA.
DR   PIR; C96730; C96730.
DR   RefSeq; NP_177218.3; NM_105729.6.
DR   AlphaFoldDB; Q8RY46; -.
DR   SMR; Q8RY46; -.
DR   BioGRID; 28618; 13.
DR   IntAct; Q8RY46; 13.
DR   STRING; 3702.AT1G70610.1; -.
DR   PaxDb; Q8RY46; -.
DR   PRIDE; Q8RY46; -.
DR   ProteomicsDB; 244582; -.
DR   EnsemblPlants; AT1G70610.1; AT1G70610.1; AT1G70610.
DR   GeneID; 843398; -.
DR   Gramene; AT1G70610.1; AT1G70610.1; AT1G70610.
DR   KEGG; ath:AT1G70610; -.
DR   Araport; AT1G70610; -.
DR   TAIR; locus:2026790; AT1G70610.
DR   eggNOG; KOG0058; Eukaryota.
DR   HOGENOM; CLU_000604_84_3_1; -.
DR   InParanoid; Q8RY46; -.
DR   OMA; RVMHDLR; -.
DR   OrthoDB; 684058at2759; -.
DR   PhylomeDB; Q8RY46; -.
DR   PRO; PR:Q8RY46; -.
DR   Proteomes; UP000006548; Chromosome 1.
DR   ExpressionAtlas; Q8RY46; baseline and differential.
DR   Genevisible; Q8RY46; AT.
DR   GO; GO:0009507; C:chloroplast; HDA:TAIR.
DR   GO; GO:0009941; C:chloroplast envelope; HDA:TAIR.
DR   GO; GO:0031969; C:chloroplast membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005739; C:mitochondrion; HDA:TAIR.
DR   GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042626; F:ATPase-coupled transmembrane transporter activity; IBA:GO_Central.
DR   Gene3D; 1.20.1560.10; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR011527; ABC1_TM_dom.
DR   InterPro; IPR036640; ABC1_TM_sf.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00664; ABC_membrane; 1.
DR   Pfam; PF00005; ABC_tran; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   SUPFAM; SSF90123; SSF90123; 1.
DR   PROSITE; PS50929; ABC_TM1F; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE   1: Evidence at protein level;
KW   ATP-binding; Chloroplast; Membrane; Nucleotide-binding; Plastid;
KW   Reference proteome; Transit peptide; Transmembrane; Transmembrane helix;
KW   Transport.
FT   TRANSIT         1..59
FT                   /note="Chloroplast"
FT                   /evidence="ECO:0000255"
FT   CHAIN           60..700
FT                   /note="ABC transporter B family member 26, chloroplastic"
FT                   /id="PRO_0000300102"
FT   TRANSMEM        137..157
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        182..202
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        268..288
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   DOMAIN          139..421
FT                   /note="ABC transmembrane type-1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   DOMAIN          455..694
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   BINDING         490..497
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ   SEQUENCE   700 AA;  78039 MW;  AA7E3EC04C608216 CRC64;
     MAQQVLGCTS RPIRVSLHRC SVITTSDTIR RKNLRFVRNP RLSFSLQSST RNYRLPSINC
     STVNGAVAET AEYYEGEGDN VSLAEKIRQC IDFLRTILPG GSWWSFSDEV DGRFIAKPVT
     VWRALSRMWE LVAEDRWVIF AAFSTLIVAA LSEITIPHFL TASIFSAQSG DIAVFHRNVK
     LLVTLCVTSG ICSGIRGCFF GIANMILVKR MRETLYSTLL FQDISFFDSQ TVGDLTSRLG
     SDCQQVSRVI GNDLNMIFRN VLQGTGALIY LLILSWPLGL CTLVICCILA AVMFVYGMYQ
     KKTAKLIQEI TASANEVAQE TYSLMRTVRV YGTEKQEFKR YNHWLQRLAD ISLRQSAAYG
     IWNWSFNTLY HATQIIAVLV GGLSILAGQI TAEQLTKFLL YSEWLIYATW WVGDNLSSLM
     QSVGASEKVF QMMDLKPSDQ FISKGTRLQR LTGHIEFVDV SFSYPSRDEV AVVQNVNISV
     HPGEVVAIVG LSGSGKSTLV NLLLQLYEPT SGQILLDGVP LKELDVKWLR QRIGYVGQEP
     KLFRTDISSN IKYGCDRNIS QEDIISAAKQ AYAHDFITAL PNGYNTIVDD DLLSGGQKQR
     IAIARAILRD PRILILDEAT SALDAESEHN VKGVLRSIGN DSATKRSVIV IAHRLSTIQA
     ADRIVAMDSG RVVEMGSHKE LLSKDGLYAR LTKRQNDAVL