ID   RO31_XENLA              Reviewed;         373 AA.
AC   P51968;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   03-AUG-2022, entry version 87.
DE   RecName: Full=Heterogeneous nuclear ribonucleoprotein A3 homolog 1;
DE   AltName: Full=hnRNP A3(A);
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=8451200; DOI=10.1093/nar/21.4.999;
RA   Good P.J., Rebbert M.L., Dawid I.B.;
RT   "Three new members of the RNP protein family in Xenopus.";
RL   Nucleic Acids Res. 21:999-1006(1993).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Note=Component of
CC       ribonucleosomes. {ECO:0000250}.
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DR   EMBL; L02956; AAA49949.1; -; mRNA.
DR   PIR; S40777; S40777.
DR   RefSeq; NP_001081318.1; NM_001087849.1.
DR   AlphaFoldDB; P51968; -.
DR   SMR; P51968; -.
DR   PRIDE; P51968; -.
DR   GeneID; 397772; -.
DR   KEGG; xla:397772; -.
DR   CTD; 397772; -.
DR   Xenbase; XB-GENE-17331347; hnrnpa3.L.
DR   OrthoDB; 1202220at2759; -.
DR   Proteomes; UP000186698; Chromosome 9_10L.
DR   Bgee; 397772; Expressed in internal ear and 19 other tissues.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   CDD; cd12763; RRM1_hnRNPA3; 1.
DR   CDD; cd12582; RRM2_hnRNPA3; 1.
DR   Gene3D; 3.30.70.330; -; 2.
DR   InterPro; IPR034513; hnRNPA3_RRM1.
DR   InterPro; IPR034516; hnRNPA3_RRM2.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR000504; RRM_dom.
DR   Pfam; PF00076; RRM_1; 2.
DR   SMART; SM00360; RRM; 2.
DR   SUPFAM; SSF54928; SSF54928; 2.
DR   PROSITE; PS50102; RRM; 2.
PE   2: Evidence at transcript level;
KW   Nucleus; Reference proteome; Repeat; Ribonucleoprotein; RNA-binding.
FT   CHAIN           1..373
FT                   /note="Heterogeneous nuclear ribonucleoprotein A3 homolog
FT                   1"
FT                   /id="PRO_0000081824"
FT   DOMAIN          27..110
FT                   /note="RRM 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   DOMAIN          118..206
FT                   /note="RRM 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   REGION          1..25
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          196..218
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          319..373
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        319..347
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   373 AA;  38580 MW;  B02D958322507386 CRC64;
     MPRGGMDDHW PSSDDQGHDP KEPEQLRKLF IGGLSFETTD DSLREHFEQW GKLTDCVVMR
     DPQTKRSRGF GFVTYSCVEE VDASMSARPH KVDGRVVEPK RAVSREDSAR PGAHLTVKKI
     FVGGIKEDTE EYHLRDYSES YGKIETIEVM EDRQSGKKRG FAFVTFDDHD TVDKIVVQKY
     HTINGHNCEV KKALSKQEMQ TASAQRGRGG GGSNFMGRGG NYGGGDGGNF GRGGGGGFGN
     RGGYGGGGGR GGGGYGGGGD GYNGFGGDGG NYGGGPGYGG RGYGGSPGYG NQGGGYGGGG
     GGYDGYNESG NFGGGNYNDF GNYGGQQQSN YGPMKGGSFS GRSSGGSGSG PYGGGYGSGG
     GGGGGGSYGG RRF