ID   RO32_XENLA              Reviewed;         385 AA.
AC   P51992;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   03-AUG-2022, entry version 91.
DE   RecName: Full=Heterogeneous nuclear ribonucleoprotein A3 homolog 2;
DE   AltName: Full=hnRNP A3(B);
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=8451200; DOI=10.1093/nar/21.4.999;
RA   Good P.J., Rebbert M.L., Dawid I.B.;
RT   "Three new members of the RNP protein family in Xenopus.";
RL   Nucleic Acids Res. 21:999-1006(1993).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Note=Component of
CC       ribonucleosomes. {ECO:0000250}.
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DR   EMBL; L02957; AAA49950.1; -; mRNA.
DR   PIR; S40778; S40778.
DR   RefSeq; NP_001081320.1; NM_001087851.1.
DR   AlphaFoldDB; P51992; -.
DR   SMR; P51992; -.
DR   MaxQB; P51992; -.
DR   PRIDE; P51992; -.
DR   GeneID; 397773; -.
DR   KEGG; xla:397773; -.
DR   CTD; 397773; -.
DR   Xenbase; XB-GENE-5879146; hnrnpa3.S.
DR   OrthoDB; 1202220at2759; -.
DR   Proteomes; UP000186698; Chromosome 9_10S.
DR   Bgee; 397773; Expressed in internal ear and 19 other tissues.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   CDD; cd12763; RRM1_hnRNPA3; 1.
DR   CDD; cd12582; RRM2_hnRNPA3; 1.
DR   Gene3D; 3.30.70.330; -; 2.
DR   InterPro; IPR034513; hnRNPA3_RRM1.
DR   InterPro; IPR034516; hnRNPA3_RRM2.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR000504; RRM_dom.
DR   Pfam; PF00076; RRM_1; 2.
DR   SMART; SM00360; RRM; 2.
DR   SUPFAM; SSF54928; SSF54928; 2.
DR   PROSITE; PS50102; RRM; 2.
PE   2: Evidence at transcript level;
KW   Nucleus; Reference proteome; Repeat; Ribonucleoprotein; RNA-binding.
FT   CHAIN           1..385
FT                   /note="Heterogeneous nuclear ribonucleoprotein A3 homolog
FT                   2"
FT                   /id="PRO_0000081825"
FT   DOMAIN          27..110
FT                   /note="RRM 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   DOMAIN          118..206
FT                   /note="RRM 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   REGION          1..24
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          199..218
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          331..385
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        331..358
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   385 AA;  39437 MW;  96895F1B997C9E9D CRC64;
     MPRGGMDDHW PSSDDQGHEP KEPEQLRKLF IGGLSFETTD DSLREHFEQW GKLTDCVVMR
     DPQTKRSRGF GFVTYSCVEE VDASMSARPH KVDGRVVEPK RAVSREDSAR PGAHLTVKKI
     FVGGIKEDTE EYHLRDYFEG YGKIETIEVM EDRQSGKKRG FAFVTFDDHD TVDKIVVQKY
     HTINLHNCEV KKALSKQEMQ TASAQRGRGG GGSNFMGRGG NYGGGDGGGG GNFGRGGGFG
     NRGGYGGGGG RGGGYGGGGD GYNGFGGDGG NYGGGPGYGG RGYGGSPGYG NQGGGYGGGG
     GGGGAGGGGY DGYNEGGNFG GGNYNDFGSY GGQQQSNYGP MKAGNFSGRS TGGSGGSSSG
     PYGGGYGSGG GGGGGGGGSY GGRRF