ID   ROA1_SCHAM              Reviewed;         342 AA.
AC   P21522;
DT   01-MAY-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1991, sequence version 1.
DT   25-MAY-2022, entry version 88.
DE   RecName: Full=Heterogeneous nuclear ribonucleoprotein A1, A2/B1 homolog;
GN   Name=HNRNP;
OS   Schistocerca americana (American grasshopper).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Polyneoptera; Orthoptera; Caelifera; Acrididea; Acridomorpha;
OC   Acridoidea; Acrididae; Cyrtacanthacridinae; Schistocerca.
OX   NCBI_TaxID=7009;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND DEVELOPMENTAL STAGE.
RX   PubMed=1901646; DOI=10.1093/nar/19.2.397;
RA   Ball E.E., Rehm E.J., Goodman C.S.;
RT   "Cloning of a grasshopper cDNA coding for a protein homologous to the A1,
RT   A2/B1 proteins of mammalian hnRNP.";
RL   Nucleic Acids Res. 19:397-397(1991).
CC   -!- FUNCTION: This protein is a component of ribonucleosomes.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- DEVELOPMENTAL STAGE: Abundant in embryos younger than 50% of embryonic
CC       development. {ECO:0000269|PubMed:1901646}.
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DR   EMBL; X54670; CAA38481.1; -; mRNA.
DR   PIR; S14432; S14432.
DR   AlphaFoldDB; P21522; -.
DR   SMR; P21522; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.70.330; -; 2.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR000504; RRM_dom.
DR   Pfam; PF00076; RRM_1; 2.
DR   SMART; SM00360; RRM; 2.
DR   SUPFAM; SSF54928; SSF54928; 2.
DR   PROSITE; PS50102; RRM; 2.
PE   2: Evidence at transcript level;
KW   Nucleus; Repeat; Ribonucleoprotein; RNA-binding.
FT   CHAIN           1..342
FT                   /note="Heterogeneous nuclear ribonucleoprotein A1, A2/B1
FT                   homolog"
FT                   /id="PRO_0000081835"
FT   DOMAIN          17..93
FT                   /note="RRM 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   DOMAIN          108..185
FT                   /note="RRM 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   REGION          180..342
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   342 AA;  35404 MW;  F8426A21C8125DD8 CRC64;
     MVNMDRENDH GEPEHVRKLF IGGLDYRTTD ESLKQHFEQW GEIVDVVVMK DPKTKRSRGF
     GFITYSRAHM VDDAQNARPH KVDGRVVEPK RAVPRTEIGR PEAGATVKKL FVGGIKEEME
     ENDLRDYFKQ YGTVVSAAIV VDKETRKKRG FAFVEFDDYD PVDKICLSRN HQIRGKHIDV
     KKALPKGDAP GGRGGGGRGG VGGGAGGGWG GGRGDWGGSA GGGGGGGWGG ADPWENGRGG
     GGDRWGGGGG GMGGGDRWGG GGGMGGGDRY GGGGGRSGGW SNDGYNSGPQ SDGFGGGYKQ
     SYGGGAVRGS SGYGGSRSAP YSDRGSRGGG GGGYGSGGGR RY