ID   ROB2_AGRRH              Reviewed;         262 AA.
AC   P49409; Q9F5H3;
DT   01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1996, sequence version 1.
DT   25-MAY-2022, entry version 62.
DE   RecName: Full=Protein-tyrosine phosphatase RolB;
DE            Short=ROL B protein;
DE            EC=3.1.3.48;
GN   Name=rolB; ORFNames=riorf15;
OS   Agrobacterium rhizogenes.
OG   Plasmid pRi1724.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Rhizobium/Agrobacterium group; Agrobacterium.
OX   NCBI_TaxID=359;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=MAFF03-01724;
RX   PubMed=8159796; DOI=10.1104/pp.104.2.801;
RA   Kiyokawa S., Kobayashi K., Kikuchi Y., Kamada H., Harada H.;
RT   "Root-inducing region of mikimopine type Ri plasmid pRi1724.";
RL   Plant Physiol. 104:801-802(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=MAFF03-01724;
RX   PubMed=7764693; DOI=10.1271/bbb.58.548;
RA   Tanaka N., Ikeda T., Oka A.;
RT   "Nucleotide sequence of the rol region of the mikimopine-type root-inducing
RT   plasmid pRi1724.";
RL   Biosci. Biotechnol. Biochem. 58:548-551(1994).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=MAFF03-01724;
RX   PubMed=11273700; DOI=10.1006/jmbi.2001.4488;
RA   Moriguchi K., Maeda Y., Satou M., Hardayani N.S.N., Kataoka M., Tanaka N.,
RA   Yoshida K.;
RT   "The complete nucleotide sequence of a plant root-inducing (Ri) plasmid
RT   indicates its chimeric structure and evolutionary relationship between
RT   tumor-inducing (Ti) and symbiotic (Sym) plasmids in Rhizobiaceae.";
RL   J. Mol. Biol. 307:771-784(2001).
CC   -!- FUNCTION: Induces differentiation and growth of neoplastic roots (hairy
CC       roots). Seems to function as a tyrosine phosphatase.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] +
CC         phosphate; Xref=Rhea:RHEA:10684, Rhea:RHEA-COMP:10136, Rhea:RHEA-
CC         COMP:10137, ChEBI:CHEBI:15377, ChEBI:CHEBI:43474, ChEBI:CHEBI:46858,
CC         ChEBI:CHEBI:82620; EC=3.1.3.48;
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAA22335.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC       Sequence=BAB16134.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; X64255; CAA45540.1; -; Genomic_DNA.
DR   EMBL; AB006689; BAA22335.1; ALT_INIT; Genomic_DNA.
DR   EMBL; AP002086; BAB16134.1; ALT_INIT; Genomic_DNA.
DR   PIR; JC2106; JC2106.
DR   RefSeq; NP_066596.1; NC_002575.1.
DR   RefSeq; WP_010900205.1; NC_002575.1.
DR   AlphaFoldDB; P49409; -.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:UniProtKB-EC.
DR   InterPro; IPR006064; Glycosidase.
DR   Pfam; PF02027; RolB_RolC; 1.
PE   4: Predicted;
KW   Hydrolase; Plasmid; Protein phosphatase.
FT   CHAIN           1..262
FT                   /note="Protein-tyrosine phosphatase RolB"
FT                   /id="PRO_0000097392"
FT   REGION          221..262
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        238..252
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   262 AA;  30097 MW;  32DD34DCDA200BF4 CRC64;
     MAPRSLFLQR FQPRDLTKAW NQLNLFDEIQ FAFLIYSQVY SKTLMDFQKR WAQGVLDLEE
     NAPPVVILKQ LAHLLKNKVC YHPPMLVDHP DLARENDRHV FVYLSREKMQ KVLEEKSITF
     GLEAVLATTM QPYRSDLVLQ EMVRAHNIAW PHRRVEEPDL EGFIAIFAST LFIHLLELKV
     TNVYGREVAC TFFVRQGTGN RSYDVIACGI TQFTKNAGVM PRPAVPSPEP DLTLRLSGPN
     QKREEGDMKP AIVNLKKETS AT