ID   ROC1_ORYSJ              Reviewed;         784 AA.
AC   Q6ZAR0; Q8S918;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 116.
DE   RecName: Full=Homeobox-leucine zipper protein ROC1;
DE   AltName: Full=GLABRA 2-like homeobox protein 1;
DE   AltName: Full=HD-ZIP protein ROC1;
DE   AltName: Full=Homeodomain transcription factor ROC1;
DE   AltName: Full=Protein RICE OUTERMOST CELL-SPECIFIC 1;
GN   Name=ROC1; Synonyms=GL2-1; OrderedLocusNames=Os08g0187500, LOC_Os08g08820;
GN   ORFNames=P0020B10.22, P0547A06.49;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, AND DEVELOPMENTAL STAGE.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=11846882; DOI=10.1046/j.1365-313x.2002.01234.x;
RA   Ito M., Sentoku N., Nishimura A., Hong S.-K., Sato Y., Matsuoka M.;
RT   "Position dependent expression of GL2-type homeobox gene, Roc1:
RT   significance for protoderm differentiation and radial pattern formation in
RT   early rice embryogenesis.";
RL   Plant J. 29:497-507(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [4]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
CC   -!- FUNCTION: Probable transcription factor that may be involved in
CC       protoderm differentiation and radial pattern formation during early
CC       embryogenesis. {ECO:0000269|PubMed:11846882}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- DEVELOPMENTAL STAGE: Specifically expressed in the L1-layer of the
CC       meristem and protoderm (epidermis) of leaf primordia. During leaf
CC       development, expressed in protoderm from plastochron 1 (P1) to P4 and
CC       down-regulated at P5 to then disappear. Expressed in the epidermis of
CC       primary rachis branch, and in the protoderm of secondary rachis branch
CC       primordia. Expressed similarly in L1-layer or protoderm in young and
CC       developed floral shoots. During embryogenesis, expressed in the
CC       outermost (epidermal) cells 2 days after pollination (DAP) and later at
CC       4 DAP in protodermal cells without any organ differentiation. In nearly
CC       mature embryo, strongly expressed in protoderm in the shoot apical
CC       meristem (SAM) and lateral organ primordia.
CC       {ECO:0000269|PubMed:11846882}.
CC   -!- SIMILARITY: Belongs to the HD-ZIP homeobox family. Class IV subfamily.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAF23064.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AB077993; BAB85750.1; -; mRNA.
DR   EMBL; AP004568; BAD03194.1; -; Genomic_DNA.
DR   EMBL; AP004656; BAD03323.1; -; Genomic_DNA.
DR   EMBL; AP008214; BAF23064.2; ALT_SEQ; Genomic_DNA.
DR   EMBL; AP014964; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_015650023.1; XM_015794537.1.
DR   AlphaFoldDB; Q6ZAR0; -.
DR   STRING; 4530.OS08T0187500-01; -.
DR   PaxDb; Q6ZAR0; -.
DR   PRIDE; Q6ZAR0; -.
DR   GeneID; 4344832; -.
DR   KEGG; osa:4344832; -.
DR   eggNOG; ENOG502QU3P; Eukaryota.
DR   InParanoid; Q6ZAR0; -.
DR   OrthoDB; 279393at2759; -.
DR   PlantReactome; R-OSA-9631623; Regulation of embryo development.
DR   Proteomes; UP000000763; Chromosome 8.
DR   Proteomes; UP000059680; Chromosome 8.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR   GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR   CDD; cd00086; homeodomain; 1.
DR   Gene3D; 3.30.530.20; -; 1.
DR   InterPro; IPR042160; GLABRA2/ANL2/PDF2/ATML1-like.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR017970; Homeobox_CS.
DR   InterPro; IPR001356; Homeobox_dom.
DR   InterPro; IPR023393; START-like_dom_sf.
DR   InterPro; IPR002913; START_lipid-bd_dom.
DR   PANTHER; PTHR45654; PTHR45654; 1.
DR   Pfam; PF00046; Homeodomain; 1.
DR   Pfam; PF01852; START; 1.
DR   SMART; SM00389; HOX; 1.
DR   SMART; SM00234; START; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   PROSITE; PS00027; HOMEOBOX_1; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
DR   PROSITE; PS50848; START; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; DNA-binding; Homeobox; Nucleus; Reference proteome;
KW   Transcription; Transcription regulation.
FT   CHAIN           1..784
FT                   /note="Homeobox-leucine zipper protein ROC1"
FT                   /id="PRO_0000331737"
FT   DOMAIN          290..522
FT                   /note="START"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00197"
FT   DNA_BIND        106..165
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT   REGION          81..115
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          155..196
FT                   /evidence="ECO:0000255"
FT   CONFLICT        246
FT                   /note="P -> S (in Ref. 1; BAB85750)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   784 AA;  84615 MW;  DAB99584407BEC30 CRC64;
     MTPARRMPPV IGRNGVAYES PSAQLPLTQA DMLDSHHLQQ ALQQQYFDQI PVTTTAAADS
     GDNMLHGRAD AGGLVDEFES KSCSENVDGA GDGLSGDDQD PNQRPRKKRY HRHTQHQIQE
     MEAFFKECPH PDDKQRKELS RELGLEPLQV KFWFQNKRTQ MKNQHERHEN AQLRAENDKL
     RAENMRYKEA LSSASCPNCG GPAALGEMSF DEHHLRVENA RLRDEIDRIS GIAAKHVGKP
     PIVSFPVLSS PLAVAAARSP LDLAGAYGVV TPGLDMFGGA GDLLRGVHPL DADKPMIVEL
     AVAAMDELVQ MAQLDEPLWS SSSEPAAALL DEEEYARMFP RGLGPKQYGL KSEASRHGAV
     VIMTHSNLVE ILMDVNQFAT VFSSIVSRAS THEVLSTGVA GNYNGALQVM SMEFQVPSPL
     VPTRESYFVR YCKNNSDGTW AVVDVSLDSL RPSPVQKCRR RPSGCLIQEM PNGYSKVTWV
     EHVEVDDSSV HNIYKPLVNS GLAFGAKRWV GTLDRQCERL ASAMASNIPN GDLGVITSVE
     GRKSMLKLAE RMVASFCGGV TASVAHQWTT LSGSGAEDVR VMTRKSVDDP GRPPGIVLNA
     ATSFWLPVPP AAVFDFLRDE TSRSEWDILS NGGAVQEMAH IANGRDHGNS VSLLRVNSAN
     SNQSNMLILQ ESCTDASGSY VVYAPVDIVA MNVVLNGGDP DYVALLPSGF AILPDGPSGN
     AQAAVGENGS GSGGGSLLTV AFQILVDSVP TAKLSLGSVA TVNSLIACTV ERIKAAVCRD
     SNPQ