ID   ROC2_ORYSJ              Reviewed;         784 AA.
AC   Q0J9X2; Q7XM83; Q7Y0W1;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2006, sequence version 1.
DT   03-AUG-2022, entry version 108.
DE   RecName: Full=Homeobox-leucine zipper protein ROC2;
DE   AltName: Full=GLABRA 2-like homeobox protein 2;
DE   AltName: Full=HD-ZIP protein ROC2;
DE   AltName: Full=Homeodomain transcription factor ROC2;
DE   AltName: Full=Protein RICE OUTERMOST CELL-SPECIFIC 2;
GN   Name=ROC2; Synonyms=GL2-2; OrderedLocusNames=Os04g0627000, LOC_Os04g53540;
GN   ORFNames=OSJNBb0060E08.16;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Ito M., Sentoku N., Nishimura A., Hong S.-K., Sato Y., Matsuoka M.;
RT   "The roles of rice GL2-type homeobox genes in epidermis differentiation.";
RL   Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=12447439; DOI=10.1038/nature01183;
RA   Feng Q., Zhang Y., Hao P., Wang S., Fu G., Huang Y., Li Y., Zhu J., Liu Y.,
RA   Hu X., Jia P., Zhang Y., Zhao Q., Ying K., Yu S., Tang Y., Weng Q.,
RA   Zhang L., Lu Y., Mu J., Lu Y., Zhang L.S., Yu Z., Fan D., Liu X., Lu T.,
RA   Li C., Wu Y., Sun T., Lei H., Li T., Hu H., Guan J., Wu M., Zhang R.,
RA   Zhou B., Chen Z., Chen L., Jin Z., Wang R., Yin H., Cai Z., Ren S., Lv G.,
RA   Gu W., Zhu G., Tu Y., Jia J., Zhang Y., Chen J., Kang H., Chen X., Shao C.,
RA   Sun Y., Hu Q., Zhang X., Zhang W., Wang L., Ding C., Sheng H., Gu J.,
RA   Chen S., Ni L., Zhu F., Chen W., Lan L., Lai Y., Cheng Z., Gu M., Jiang J.,
RA   Li J., Hong G., Xue Y., Han B.;
RT   "Sequence and analysis of rice chromosome 4.";
RL   Nature 420:316-320(2002).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [4]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [5]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
CC   -!- FUNCTION: Probable transcription factor. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the HD-ZIP homeobox family. Class IV subfamily.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAC77155.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC       Sequence=CAE04753.3; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AB101645; BAC77155.1; ALT_INIT; mRNA.
DR   EMBL; AL606669; CAE04753.3; ALT_SEQ; Genomic_DNA.
DR   EMBL; AP008210; BAF15865.1; -; Genomic_DNA.
DR   EMBL; AP014960; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_015636338.1; XM_015780852.1.
DR   RefSeq; XP_015636339.1; XM_015780853.1.
DR   RefSeq; XP_015636340.1; XM_015780854.1.
DR   AlphaFoldDB; Q0J9X2; -.
DR   SMR; Q0J9X2; -.
DR   STRING; 4530.OS04T0627000-02; -.
DR   iPTMnet; Q0J9X2; -.
DR   PaxDb; Q0J9X2; -.
DR   PRIDE; Q0J9X2; -.
DR   GeneID; 4337074; -.
DR   KEGG; osa:4337074; -.
DR   eggNOG; ENOG502QU3P; Eukaryota.
DR   HOGENOM; CLU_015002_3_2_1; -.
DR   InParanoid; Q0J9X2; -.
DR   OrthoDB; 279393at2759; -.
DR   Proteomes; UP000000763; Chromosome 4.
DR   Proteomes; UP000059680; Chromosome 4.
DR   Genevisible; Q0J9X2; OS.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR   GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR   CDD; cd00086; homeodomain; 1.
DR   Gene3D; 3.30.530.20; -; 1.
DR   InterPro; IPR042160; GLABRA2/ANL2/PDF2/ATML1-like.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR017970; Homeobox_CS.
DR   InterPro; IPR001356; Homeobox_dom.
DR   InterPro; IPR023393; START-like_dom_sf.
DR   InterPro; IPR002913; START_lipid-bd_dom.
DR   PANTHER; PTHR45654; PTHR45654; 1.
DR   Pfam; PF00046; Homeodomain; 1.
DR   Pfam; PF01852; START; 1.
DR   SMART; SM00389; HOX; 1.
DR   SMART; SM00234; START; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   PROSITE; PS00027; HOMEOBOX_1; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
DR   PROSITE; PS50848; START; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; DNA-binding; Homeobox; Nucleus; Reference proteome;
KW   Transcription; Transcription regulation.
FT   CHAIN           1..784
FT                   /note="Homeobox-leucine zipper protein ROC2"
FT                   /id="PRO_0000331738"
FT   DOMAIN          286..523
FT                   /note="START"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00197"
FT   DNA_BIND        104..163
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT   REGION          60..113
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          158..234
FT                   /evidence="ECO:0000255"
FT   CONFLICT        299
FT                   /note="A -> P (in Ref. 1; BAC77155)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        602
FT                   /note="A -> V (in Ref. 1; BAC77155)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        611
FT                   /note="P -> S (in Ref. 1; BAC77155)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        616
FT                   /note="D -> H (in Ref. 1; BAC77155)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   784 AA;  85259 MW;  AA9D3ABD0720642F CRC64;
     MMIPARHMPS MIGRNGAAYG SSSALSLSQP NLLDNHQFQQ AFQHQQQQHH LLDQIPATTA
     ESGDNMIRSR ASDPLGGDEF ESKSGSENVD GVSVDDQDPN QRPRKKRYHR HTQHQIQEME
     AFFKECPHPD DKQRKELSRE LGLEPLQVKF WFQNKRTQMK NQHERHENSQ LRSDNEKLRA
     ENMRYKEALS SASCPNCGGP AALGEMSFDE HHLRIENARL REEIDRISAI AAKYVGKPMV
     PFPVLSNPMA AAASRAPLDL PVAPYGVPGD MFGGGGAGEL LRGVQSEVDK PMIVELAVAA
     MEELVRMAQL DEPLWSVAPP LDATAAAMET LSEEEYARMF PRGLGPKQYG LRSEASRDSA
     VVIMTHANLV EILMDANQYA AVFSNIVSRA ITLEVLSTGV AGNYNGALQV MSVEFQVPSP
     LVPTRESYFV RYCKQNADGT WAVVDVSLDS LRPSPVLKCR RRPSGCLIQE MPNGYSKVTW
     VEHVEVDDRS VHNIYKLLVN SGLAFGARRW VGTLDRQCER LASVMASNIP TSDIGVITSS
     EGRKSMLKLA ERMVVSFCGG VTASVAHQWT TLSGSGAEDV RVMTRKSVDD PGRPPGIVLN
     AATSFWLPVP PKRVFDFLRD ESSRSEWDIL SNGGIVQEMA HIANGRDQGN CVSLLRVNSS
     NSNQSNMLIL QESCTDASGS YVIYAPVDVV AMNVVLNGGD PDYVALLPSG FAILPDGPAH
     DGGDGDGGVG VGSGGSLLTV AFQILVDSVP TAKLSLGSVA TVNSLIACTV ERIKAAVSGE
     SNPQ