ID   ROC3_ORYSJ              Reviewed;         882 AA.
AC   Q336P2; A3C7K9; F4MGZ9; Q7Y0W0; Q8W3I3;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 1.
DT   03-AUG-2022, entry version 112.
DE   RecName: Full=Homeobox-leucine zipper protein ROC3;
DE   AltName: Full=GLABRA 2-like homeobox protein 3;
DE   AltName: Full=HD-ZIP protein ROC3;
DE   AltName: Full=Homeodomain transcription factor ROC3;
DE   AltName: Full=Protein RICE OUTERMOST CELL-SPECIFIC 3;
GN   Name=ROC3; Synonyms=GL2-3; OrderedLocusNames=Os10g0575600, LOC_Os10g42490;
GN   ORFNames=OsJ_031281, OSJNBa0027L23.2;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Ito M., Sentoku N., Nishimura A., Hong S.-K., Sato Y., Matsuoka M.;
RT   "The roles of rice GL2-type homeobox genes in epidermis differentiation.";
RL   Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=12791992; DOI=10.1126/science.1083523;
RA   Yu Y., Rambo T., Currie J., Saski C., Kim H.-R., Collura K., Thompson S.,
RA   Simmons J., Yang T.-J., Nah G., Patel A.J., Thurmond S., Henry D.,
RA   Oates R., Palmer M., Pries G., Gibson J., Anderson H., Paradkar M.,
RA   Crane L., Dale J., Carver M.B., Wood T., Frisch D., Engler F.,
RA   Soderlund C., Palmer L.E., Teytelman L., Nascimento L., De la Bastide M.,
RA   Spiegel L., Ware D., O'Shaughnessy A., Dike S., Dedhia N., Preston R.,
RA   Huang E., Ferraro K., Kuit K., Miller B., Zutavern T., Katzenberger F.,
RA   Muller S., Balija V., Martienssen R.A., Stein L., Minx P., Johnson D.,
RA   Cordum H., Mardis E., Cheng Z., Jiang J., Wilson R., McCombie W.R.,
RA   Wing R.A., Yuan Q., Ouyang S., Liu J., Jones K.M., Gansberger K.,
RA   Moffat K., Hill J., Tsitrin T., Overton L., Bera J., Kim M., Jin S.,
RA   Tallon L., Ciecko A., Pai G., Van Aken S., Utterback T., Reidmuller S.,
RA   Bormann J., Feldblyum T., Hsiao J., Zismann V., Blunt S., de Vazeille A.R.,
RA   Shaffer T., Koo H., Suh B., Yang Q., Haas B., Peterson J., Pertea M.,
RA   Volfovsky N., Wortman J., White O., Salzberg S.L., Fraser C.M., Buell C.R.,
RA   Messing J., Song R., Fuks G., Llaca V., Kovchak S., Young S., Bowers J.E.,
RA   Paterson A.H., Johns M.A., Mao L., Pan H., Dean R.A.;
RT   "In-depth view of structure, activity, and evolution of rice chromosome
RT   10.";
RL   Science 300:1566-1569(2003).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [4]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [5]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [6]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
CC   -!- FUNCTION: Probable transcription factor. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the HD-ZIP homeobox family. Class IV subfamily.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAL67592.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC       Sequence=BAC77156.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC       Sequence=EAZ17072.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AB101646; BAC77156.1; ALT_INIT; mRNA.
DR   EMBL; AC018929; AAL67592.1; ALT_INIT; Genomic_DNA.
DR   EMBL; DP000086; ABB48020.1; -; Genomic_DNA.
DR   EMBL; DP000086; ABB48021.1; -; Genomic_DNA.
DR   EMBL; AP008216; BAF27318.1; -; Genomic_DNA.
DR   EMBL; AP014966; BAT12196.1; -; Genomic_DNA.
DR   EMBL; CM000147; EAZ17072.1; ALT_SEQ; Genomic_DNA.
DR   RefSeq; XP_015613461.1; XM_015757975.1.
DR   AlphaFoldDB; Q336P2; -.
DR   SMR; Q336P2; -.
DR   STRING; 4530.OS10T0575600-01; -.
DR   PaxDb; Q336P2; -.
DR   PRIDE; Q336P2; -.
DR   EnsemblPlants; Os10t0575600-01; Os10t0575600-01; Os10g0575600.
DR   GeneID; 4349488; -.
DR   Gramene; Os10t0575600-01; Os10t0575600-01; Os10g0575600.
DR   KEGG; osa:4349488; -.
DR   eggNOG; ENOG502QU3P; Eukaryota.
DR   HOGENOM; CLU_015002_2_1_1; -.
DR   InParanoid; Q336P2; -.
DR   OMA; WVEHMEM; -.
DR   OrthoDB; 223056at2759; -.
DR   Proteomes; UP000000763; Chromosome 10.
DR   Proteomes; UP000007752; Chromosome 10.
DR   Proteomes; UP000059680; Chromosome 10.
DR   Genevisible; Q336P2; OS.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR   GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR   CDD; cd00086; homeodomain; 1.
DR   Gene3D; 3.30.530.20; -; 1.
DR   InterPro; IPR042160; GLABRA2/ANL2/PDF2/ATML1-like.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR017970; Homeobox_CS.
DR   InterPro; IPR001356; Homeobox_dom.
DR   InterPro; IPR023393; START-like_dom_sf.
DR   InterPro; IPR002913; START_lipid-bd_dom.
DR   PANTHER; PTHR45654; PTHR45654; 2.
DR   Pfam; PF00046; Homeodomain; 1.
DR   Pfam; PF01852; START; 1.
DR   SMART; SM00389; HOX; 1.
DR   SMART; SM00234; START; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   PROSITE; PS00027; HOMEOBOX_1; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
DR   PROSITE; PS50848; START; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; DNA-binding; Homeobox; Nucleus; Reference proteome;
KW   Transcription; Transcription regulation.
FT   CHAIN           1..882
FT                   /note="Homeobox-leucine zipper protein ROC3"
FT                   /id="PRO_0000331740"
FT   DOMAIN          340..584
FT                   /note="START"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00197"
FT   DNA_BIND        134..193
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT   REGION          104..144
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          782..820
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          200..263
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   882 AA;  94667 MW;  5C83A6D6F6B7B9FC CRC64;
     MRRMFGDCQV LSSMAAMAGA ASSADALFAS PLIPNPALAG FMSSSAAMPF HHFSNAAATL
     IPKEEGLMGG LHVAKDEGMD LEMDMELSGG SGSAHLDGLL SFADVDDDHK PQHSGHDQPP
     DAAQPSGAAG GNAKKKRYHR HTAHQIQQME ALFKECPHPD DKQRLKLSQE LGLKPRQVKF
     WFQNRRTQMK AQQDRADNVI LRAENENLKS DNFRLQAAIR NVVCPNCGHA AVLADMSYEE
     QQLRIENARL KDELDRLACI ATRYGGGGGR QPVLSTSALS CISAPPPVLM PPLDLDMNVY
     SRHFAEQAPV MGCGDLIPPP VVPQHDGAAA YMGAMMAPVQ EQDKQLVVDL AATAADQLAR
     MCRAGEPLWV RQRGAEVMAV EEHARMFSWP VDGAKQGDGG AVARAEGTRD NAVVIMNSIN
     LVDAFLDANK WMELFPSIVC KARTIQIINH GAASGHLGSG TLLLMQAEVQ FLSPLVAARE
     VVFFRYCVHN ADEGSWAIVD FPAEGFEEGL LQASVVRCRR RPSGCIIQDM PNGYSRVVWV
     EHMEMVGEEK PLQPVFRDYV ASGAAFGATR WLSILQRQCE RLASELARNI ADLGVIRTPE
     ARTNMMKLSQ RMITTFCANI SASGTQSWTA LSDSTQDTIR VTTRKNTEPG QPSGVILTAV
     STSWLPFTHQ QVFELLADEQ QRCQLEILSN GGSLHEVAHI ANGSHPRNCI SLLRINAASN
     SSQNVELLLQ ESSTHPDGGS LVVFATVDVD AIQVTMSGED PSYIPLLPLG FAIFPATSPS
     PAAAPTISSS TTTTTGNGNG ETSSTPPRNS SSNNNNADEL LPPNGCLLTV GMQVLASAVP
     SAKLNLSSVT AINSHVCNAI HQITAALKSS AGGAGGEPAS DQ