ID   ROC5_ORYSJ              Reviewed;         804 AA.
AC   Q6EPF0; B9F1M1; Q7Y0V8;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 124.
DE   RecName: Full=Homeobox-leucine zipper protein ROC5;
DE   AltName: Full=GLABRA 2-like homeobox protein 5;
DE   AltName: Full=HD-ZIP protein ROC5;
DE   AltName: Full=Homeodomain transcription factor ROC5;
DE   AltName: Full=Protein RICE OUTERMOST CELL-SPECIFIC 5;
GN   Name=ROC5; Synonyms=GL2-5; OrderedLocusNames=Os02g0674800, LOC_Os02g45250;
GN   ORFNames=OsJ_07908 {ECO:0000312|EMBL:EEE57563.1}, P0657H12.28;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Ito M., Sentoku N., Nishimura A., Hong S.-K., Sato Y., Matsuoka M.;
RT   "The roles of rice GL2-type homeobox genes in epidermis differentiation.";
RL   Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [4]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
CC   -!- FUNCTION: Probable transcription factor. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the HD-ZIP homeobox family. Class IV subfamily.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAC77158.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AB101648; BAC77158.1; ALT_INIT; mRNA.
DR   EMBL; AP005885; BAD29470.1; -; Genomic_DNA.
DR   EMBL; AP008208; BAF09632.1; -; Genomic_DNA.
DR   EMBL; AP014958; BAS80261.1; -; Genomic_DNA.
DR   EMBL; CM000139; EEE57563.1; -; Genomic_DNA.
DR   RefSeq; XP_015625616.1; XM_015770130.1.
DR   AlphaFoldDB; Q6EPF0; -.
DR   SMR; Q6EPF0; -.
DR   STRING; 4530.OS02T0674800-01; -.
DR   PaxDb; Q6EPF0; -.
DR   PRIDE; Q6EPF0; -.
DR   EnsemblPlants; Os02t0674800-01; Os02t0674800-01; Os02g0674800.
DR   GeneID; 4330297; -.
DR   Gramene; Os02t0674800-01; Os02t0674800-01; Os02g0674800.
DR   KEGG; osa:4330297; -.
DR   eggNOG; ENOG502QUAY; Eukaryota.
DR   HOGENOM; CLU_015002_2_1_1; -.
DR   InParanoid; Q6EPF0; -.
DR   OMA; PCIGMRP; -.
DR   OrthoDB; 226429at2759; -.
DR   Proteomes; UP000000763; Chromosome 2.
DR   Proteomes; UP000007752; Chromosome 2.
DR   Proteomes; UP000059680; Chromosome 2.
DR   Genevisible; Q6EPF0; OS.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR   GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR   CDD; cd00086; homeodomain; 1.
DR   Gene3D; 3.30.530.20; -; 1.
DR   InterPro; IPR042160; GLABRA2/ANL2/PDF2/ATML1-like.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR017970; Homeobox_CS.
DR   InterPro; IPR001356; Homeobox_dom.
DR   InterPro; IPR023393; START-like_dom_sf.
DR   InterPro; IPR002913; START_lipid-bd_dom.
DR   PANTHER; PTHR45654; PTHR45654; 1.
DR   Pfam; PF00046; Homeodomain; 1.
DR   Pfam; PF01852; START; 1.
DR   SMART; SM00389; HOX; 1.
DR   SMART; SM00234; START; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   PROSITE; PS00027; HOMEOBOX_1; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
DR   PROSITE; PS50848; START; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; DNA-binding; Homeobox; Nucleus; Reference proteome;
KW   Transcription; Transcription regulation.
FT   CHAIN           1..804
FT                   /note="Homeobox-leucine zipper protein ROC5"
FT                   /id="PRO_0000331742"
FT   DOMAIN          305..549
FT                   /note="START"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00197"
FT   DNA_BIND        98..157
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT   REGION          47..106
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          146..223
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   804 AA;  86047 MW;  390D1C72BC95247D CRC64;
     MSFGGLFDGG GGGGMQFPFA SGFASSPALS LALDNAGGGI GGRMLGGGAG AGSSAGGAMT
     RDTEAENDSR SGSDHLDAIS AAGEDDVEDA EPSNSRKRKK RYHRHTPQQI QELEALFKEC
     PHPDEKQRAE LSRRLSLDAR QVKFWFQNRR TQMKTQLERH ENALLKQEND KLRAENMTIR
     EAMRSPMCGS CGSPAMLGEV SLEEQHLRIE NARLKDELNR VCALATKFLG KPISLLSPPP
     LLQPHLSLPM PNSSLELAIG GIGGLGSLGT LPGCMNEFAG GVSSPMGTVI TPARATGAAI
     PSLVGNIDRS VFLELAISAM DELVKMAQMD DPLWVPALPG SPSKEVLNFE EYLHSFLPCI
     GMKPAGYVSE ASRESGLVII DNSLALVETL MDERRWSDMF SCMIAKATVL EEVSTGIAGS
     RNGALLLMKA ELQVLSPLVP IREVTFLRFC KQLAEGAWAV VDVSIDGLVR DHNSGTAPTG
     GNVKCRRVPS GCVMQDTPNG YCKVTWVEHT EYDEASVHQL YRPLLRSGLA FGARRWLATL
     QRQCECLAIL MSSATVTAND STAISQEGKR SMLKLARRMT ENFCAGVSAS SAREWSKLDG
     ATGSIGEDVR VMARKSVSEP GEPPGVVLSA ATSVWVPVAP EKLFNFLRDE QLRAEWDILS
     NGGPMQEMTQ IAKGQRDGNS VSLLRASAVS ANQSSMLILQ ETCTDASGSI VVYAPVDIPA
     MQLVMNGGDS TYVALLPSGF AILPDGPRIG ATGYETGGSL LTVAFQILVN NQPTAKLTVE
     SVETVNNLIS CTIKKIKTAL QCDA