ID   RODL_EMENI              Reviewed;         157 AA.
AC   P28346; C8V9N5; Q5ASC7;
DT   01-DEC-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-1992, sequence version 1.
DT   25-MAY-2022, entry version 97.
DE   RecName: Full=Rodlet protein;
DE   Flags: Precursor;
GN   Name=rodA; ORFNames=AN8803;
OS   Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 /
OS   M139) (Aspergillus nidulans).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Nidulantes.
OX   NCBI_TaxID=227321;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2065971; DOI=10.1101/gad.5.7.1161;
RA   Stringer M.A., Dean R.A., Sewall T.C., Timberlake W.E.;
RT   "Rodletless, a new Aspergillus developmental mutant induced by directed
RT   gene inactivation.";
RL   Genes Dev. 5:1161-1171(1991).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX   PubMed=16372000; DOI=10.1038/nature04341;
RA   Galagan J.E., Calvo S.E., Cuomo C., Ma L.-J., Wortman J.R., Batzoglou S.,
RA   Lee S.-I., Bastuerkmen M., Spevak C.C., Clutterbuck J., Kapitonov V.,
RA   Jurka J., Scazzocchio C., Farman M.L., Butler J., Purcell S., Harris S.,
RA   Braus G.H., Draht O., Busch S., D'Enfert C., Bouchier C., Goldman G.H.,
RA   Bell-Pedersen D., Griffiths-Jones S., Doonan J.H., Yu J., Vienken K.,
RA   Pain A., Freitag M., Selker E.U., Archer D.B., Penalva M.A., Oakley B.R.,
RA   Momany M., Tanaka T., Kumagai T., Asai K., Machida M., Nierman W.C.,
RA   Denning D.W., Caddick M.X., Hynes M., Paoletti M., Fischer R., Miller B.L.,
RA   Dyer P.S., Sachs M.S., Osmani S.A., Birren B.W.;
RT   "Sequencing of Aspergillus nidulans and comparative analysis with A.
RT   fumigatus and A. oryzae.";
RL   Nature 438:1105-1115(2005).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX   PubMed=19146970; DOI=10.1016/j.fgb.2008.12.003;
RA   Wortman J.R., Gilsenan J.M., Joardar V., Deegan J., Clutterbuck J.,
RA   Andersen M.R., Archer D., Bencina M., Braus G., Coutinho P., von Dohren H.,
RA   Doonan J., Driessen A.J., Durek P., Espeso E., Fekete E., Flipphi M.,
RA   Estrada C.G., Geysens S., Goldman G., de Groot P.W., Hansen K.,
RA   Harris S.D., Heinekamp T., Helmstaedt K., Henrissat B., Hofmann G.,
RA   Homan T., Horio T., Horiuchi H., James S., Jones M., Karaffa L.,
RA   Karanyi Z., Kato M., Keller N., Kelly D.E., Kiel J.A., Kim J.M.,
RA   van der Klei I.J., Klis F.M., Kovalchuk A., Krasevec N., Kubicek C.P.,
RA   Liu B., Maccabe A., Meyer V., Mirabito P., Miskei M., Mos M., Mullins J.,
RA   Nelson D.R., Nielsen J., Oakley B.R., Osmani S.A., Pakula T., Paszewski A.,
RA   Paulsen I., Pilsyk S., Pocsi I., Punt P.J., Ram A.F., Ren Q., Robellet X.,
RA   Robson G., Seiboth B., van Solingen P., Specht T., Sun J.,
RA   Taheri-Talesh N., Takeshita N., Ussery D., vanKuyk P.A., Visser H.,
RA   van de Vondervoort P.J., de Vries R.P., Walton J., Xiang X., Xiong Y.,
RA   Zeng A.P., Brandt B.W., Cornell M.J., van den Hondel C.A., Visser J.,
RA   Oliver S.G., Turner G.;
RT   "The 2008 update of the Aspergillus nidulans genome annotation: a community
RT   effort.";
RL   Fungal Genet. Biol. 46:S2-13(2009).
CC   -!- FUNCTION: Contributes to surface hydrophobicity, which is important for
CC       processes such as association of hyphae in reproductive structures,
CC       dispersal of aerial spores and adhesion of pathogens to host
CC       structures. Important for the formation of hydrophobic rodlet layers of
CC       asexually-produced spores.
CC   -!- SUBCELLULAR LOCATION: Secreted, cell wall.
CC   -!- DEVELOPMENTAL STAGE: Accumulates at about the time sterigmata appear
CC       and remains at high levels throughout the final stages of conidiophore
CC       formation and during spore differentiation and maturation.
CC   -!- INDUCTION: By brlA.
CC   -!- SIMILARITY: Belongs to the fungal hydrophobin family. {ECO:0000305}.
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DR   EMBL; M61113; AAA33321.1; -; Genomic_DNA.
DR   EMBL; AACD01000161; EAA60596.1; -; Genomic_DNA.
DR   EMBL; BN001303; CBF77990.1; -; Genomic_DNA.
DR   PIR; A40323; A40323.
DR   RefSeq; XP_682072.1; XM_676980.1.
DR   AlphaFoldDB; P28346; -.
DR   SMR; P28346; -.
DR   STRING; 162425.CADANIAP00006259; -.
DR   PRIDE; P28346; -.
DR   EnsemblFungi; CBF77990; CBF77990; ANIA_08803.
DR   EnsemblFungi; EAA60596; EAA60596; AN8803.2.
DR   GeneID; 2868430; -.
DR   KEGG; ani:AN8803.2; -.
DR   VEuPathDB; FungiDB:AN8803; -.
DR   eggNOG; ENOG502T10M; Eukaryota.
DR   HOGENOM; CLU_106380_1_0_1; -.
DR   InParanoid; P28346; -.
DR   OMA; MTVKQAQ; -.
DR   OrthoDB; 1513191at2759; -.
DR   Proteomes; UP000000560; Chromosome III.
DR   Proteomes; UP000005890; Unassembled WGS sequence.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR   GO; GO:0009277; C:fungal-type cell wall; IEA:InterPro.
DR   GO; GO:0031160; C:spore wall; IDA:AspGD.
DR   GO; GO:0005199; F:structural constituent of cell wall; IEA:InterPro.
DR   GO; GO:0042243; P:asexual spore wall assembly; IMP:AspGD.
DR   InterPro; IPR001338; Hydrophobin.
DR   InterPro; IPR019778; Hydrophobin_CS.
DR   Pfam; PF01185; Hydrophobin; 1.
DR   SMART; SM00075; HYDRO; 1.
DR   PROSITE; PS00956; HYDROPHOBIN; 1.
PE   2: Evidence at transcript level;
KW   Cell wall; Cell wall biogenesis/degradation; Disulfide bond; Glycoprotein;
KW   Reference proteome; Secreted; Signal.
FT   SIGNAL          1..41
FT                   /evidence="ECO:0000255"
FT   CHAIN           42..157
FT                   /note="Rodlet protein"
FT                   /id="PRO_0000013508"
FT   CARBOHYD        47
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   DISULFID        57..131
FT                   /evidence="ECO:0000250"
FT   DISULFID        65..125
FT                   /evidence="ECO:0000250"
FT   DISULFID        66..106
FT                   /evidence="ECO:0000250"
FT   DISULFID        132..150
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   157 AA;  15643 MW;  69F08B2C7ED28277 CRC64;
     MKFSIAAAVV AFAASVAALP PAHDSQFAGN GVGNKGNSNV KFPVPENVTV KQASDKCGDQ
     AQLSCCNKAT YAGDTTTVDE GLLSGALSGL IGAGSGAEGL GLFDQCSKLD VAVLIGIQDL
     VNQKCKQNIA CCQNSPSSAD GNLIGVGLPC VALGSIL