ID   ROGDI_RAT               Reviewed;         287 AA.
AC   Q4V7D2;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2005, sequence version 1.
DT   03-AUG-2022, entry version 84.
DE   RecName: Full=Protein rogdi homolog;
GN   Name=Rogdi;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [2]
RP   SUBCELLULAR LOCATION, AND TISSUE SPECIFICITY.
RX   PubMed=29150638; DOI=10.1038/s41598-017-16004-1;
RA   Riemann D., Wallrafen R., Dresbach T.;
RT   "The Kohlschuetter-Toenz syndrome associated gene Rogdi encodes a novel
RT   presynaptic protein.";
RL   Sci. Rep. 7:15791-15791(2017).
CC   -!- SUBUNIT: Monomer. {ECO:0000250|UniProtKB:Q9GZN7}.
CC   -!- SUBCELLULAR LOCATION: Nucleus envelope {ECO:0000250|UniProtKB:Q9GZN7}.
CC       Presynapse {ECO:0000269|PubMed:29150638}. Cell projection, axon
CC       {ECO:0000269|PubMed:29150638}. Perikaryon
CC       {ECO:0000269|PubMed:29150638}. Cell projection, dendrite
CC       {ECO:0000269|PubMed:29150638}. Cytoplasmic vesicle, secretory vesicle,
CC       synaptic vesicle {ECO:0000269|PubMed:29150638}. Note=Detected primarily
CC       at presynaptic sites on axons, and to a lesser degree in soma and
CC       dendrites. Not detected at post-synaptic sites.
CC       {ECO:0000269|PubMed:29150638}.
CC   -!- TISSUE SPECIFICITY: Detected at synapses in the stratum lucidum in the
CC       hippocampus CA3 region (at protein level).
CC       {ECO:0000269|PubMed:29150638}.
CC   -!- SIMILARITY: Belongs to the rogdi family. {ECO:0000305}.
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DR   EMBL; BC098001; AAH98001.1; -; mRNA.
DR   RefSeq; NP_001020035.1; NM_001024864.1.
DR   AlphaFoldDB; Q4V7D2; -.
DR   SMR; Q4V7D2; -.
DR   BioGRID; 251991; 1.
DR   STRING; 10116.ENSRNOP00000004176; -.
DR   PaxDb; Q4V7D2; -.
DR   PRIDE; Q4V7D2; -.
DR   Ensembl; ENSRNOT00000004176; ENSRNOP00000004176; ENSRNOG00000003125.
DR   GeneID; 287061; -.
DR   KEGG; rno:287061; -.
DR   UCSC; RGD:1560021; rat.
DR   CTD; 79641; -.
DR   RGD; 1560021; Rogdi.
DR   eggNOG; KOG3992; Eukaryota.
DR   GeneTree; ENSGT00390000007164; -.
DR   HOGENOM; CLU_062094_0_1_1; -.
DR   InParanoid; Q4V7D2; -.
DR   OMA; NILMECA; -.
DR   OrthoDB; 1051737at2759; -.
DR   PhylomeDB; Q4V7D2; -.
DR   TreeFam; TF105859; -.
DR   PRO; PR:Q4V7D2; -.
DR   Proteomes; UP000002494; Chromosome 10.
DR   Bgee; ENSRNOG00000003125; Expressed in kidney and 20 other tissues.
DR   Genevisible; Q4V7D2; RN.
DR   GO; GO:0070161; C:anchoring junction; IEA:UniProtKB-KW.
DR   GO; GO:0030424; C:axon; IEA:UniProtKB-SubCell.
DR   GO; GO:0030425; C:dendrite; IEA:UniProtKB-SubCell.
DR   GO; GO:0005635; C:nuclear envelope; ISO:RGD.
DR   GO; GO:0043204; C:perikaryon; IEA:UniProtKB-SubCell.
DR   GO; GO:0098793; C:presynapse; IDA:SynGO.
DR   GO; GO:0043291; C:RAVE complex; IBA:GO_Central.
DR   GO; GO:0008021; C:synaptic vesicle; IEA:UniProtKB-SubCell.
DR   GO; GO:0007420; P:brain development; ISO:RGD.
DR   GO; GO:0030097; P:hemopoiesis; ISO:RGD.
DR   GO; GO:0022008; P:neurogenesis; ISO:RGD.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; ISO:RGD.
DR   GO; GO:0008284; P:positive regulation of cell population proliferation; ISO:RGD.
DR   InterPro; IPR028241; RAVE2/Rogdi.
DR   PANTHER; PTHR13618; PTHR13618; 1.
DR   Pfam; PF10259; Rogdi_lz; 1.
PE   1: Evidence at protein level;
KW   Acetylation; Cell projection; Cytoplasmic vesicle; Nucleus;
KW   Reference proteome; Synapse.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250|UniProtKB:Q9GZN7"
FT   CHAIN           2..287
FT                   /note="Protein rogdi homolog"
FT                   /id="PRO_0000315667"
FT   MOD_RES         2
FT                   /note="N-acetylalanine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9GZN7"
SQ   SEQUENCE   287 AA;  32205 MW;  175D990636AE4394 CRC64;
     MATAMAASAA ERAVLEEEFR WLLHAEVHAV LRQLQDILKE ASLRFTLPGP STEGPAKQEN
     FILGSCGTDQ VKGVLTLQGD ALSQADVNLK MPRNNQLLHF AFREDKQWKL QQIQDARNHV
     SQAIYLLANR DESYQFKTGA EVLKLMDAVM LQLTRARNRL TTPATLTLPE IAASGLTRMF
     APTLPSDLLV NVYINLNKLC LTVYQLHTLQ PTSTKNFRPA GGAVLHSPGA MFEWGSQRLE
     VSHVHKVECV IPWLNDALVY FTVSLQLCQQ LKDKISVFSS YWSSRPF