ROLB_NICGL
ID ROLB_NICGL Reviewed; 211 AA.
AC P09178;
DT 01-JUL-1989, integrated into UniProtKB/Swiss-Prot.
DT 01-JUL-1989, sequence version 1.
DT 25-MAY-2022, entry version 56.
DE RecName: Full=Protein-tyrosine phosphatase rolB;
DE Short=Protein ROL B;
DE EC=3.1.3.48;
GN Name=ROLB;
OS Nicotiana glauca (Glaucous tobacco) (Tree tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4090;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA Furner I.J., Huffman G.A., Amasino R.M., Garfinkel D.J., Gordon M.P.,
RA Nester E.W.;
RT "An Agrobacterium transformation in the evolution of the genus Nicotiana.";
RL Nature 319:422-427(1986).
CC -!- FUNCTION: Induces differentiation and growth of neoplastic roots (hairy
CC roots). Seems to function as a tyrosine phosphatase.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] +
CC phosphate; Xref=Rhea:RHEA:10684, Rhea:RHEA-COMP:10136, Rhea:RHEA-
CC COMP:10137, ChEBI:CHEBI:15377, ChEBI:CHEBI:43474, ChEBI:CHEBI:46858,
CC ChEBI:CHEBI:82620; EC=3.1.3.48;
CC -!- SIMILARITY: Belongs to the rolB/rolC family. {ECO:0000305}.
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DR EMBL; X03432; CAA27161.1; -; Genomic_DNA.
DR PIR; C27259; C27259.
DR AlphaFoldDB; P09178; -.
DR GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:UniProtKB-EC.
DR InterPro; IPR006064; Glycosidase.
DR Pfam; PF02027; RolB_RolC; 1.
PE 3: Inferred from homology;
KW Hydrolase; Protein phosphatase.
FT CHAIN 1..211
FT /note="Protein-tyrosine phosphatase rolB"
FT /id="PRO_0000097401"
SQ SEQUENCE 211 AA; 24862 MW; 7DB814CF2311F81F CRC64;
MASQSQFHPR FQPRNLTPAG KQINLSKEIQ SAFMTYSEVY SKTLLDYQKR WADVIFDLEE
KSLRMDILKQ LAELLKNKIC YHPPMFVEQP DLARERDQRV FIYLSREKMQ KVLEEQSITV
GMEAVLATTI QPYRSDLAVQ EMLRVHNRAW PHRRMEERDL ECFIAIFAST LFIHLTTLKV
TNLYGREVDC TFFVRRASTN RPYDVVAFGT T