ID   AB28G_ARATH             Reviewed;        1109 AA.
AC   Q9FF46;
DT   27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 141.
DE   RecName: Full=ABC transporter G family member 28;
DE            Short=ABC transporter ABCG.28;
DE            Short=AtABCG28;
DE   AltName: Full=Putative white-brown complex homolog protein 29;
DE            Short=AtWBC29;
GN   Name=ABCG28; Synonyms=WBC29; OrderedLocusNames=At5g60740;
GN   ORFNames=MUP24.16;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=9330910; DOI=10.1093/dnares/4.3.215;
RA   Sato S., Kotani H., Nakamura Y., Kaneko T., Asamizu E., Fukami M.,
RA   Miyajima N., Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 5. I. Sequence
RT   features of the 1.6 Mb regions covered by twenty physically assigned P1
RT   clones.";
RL   DNA Res. 4:215-230(1997).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=11346655; DOI=10.1074/jbc.m103104200;
RA   Sanchez-Fernandez R., Davies T.G., Coleman J.O., Rea P.A.;
RT   "The Arabidopsis thaliana ABC protein superfamily, a complete inventory.";
RL   J. Biol. Chem. 276:30231-30244(2001).
RN   [4]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=18299247; DOI=10.1016/j.tplants.2008.02.001;
RA   Verrier P.J., Bird D., Burla B., Dassa E., Forestier C., Geisler M.,
RA   Klein M., Kolukisaoglu H.U., Lee Y., Martinoia E., Murphy A., Rea P.A.,
RA   Samuels L., Schulz B., Spalding E.J., Yazaki K., Theodoulou F.L.;
RT   "Plant ABC proteins - a unified nomenclature and updated inventory.";
RL   Trends Plant Sci. 13:151-159(2008).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCG family.
CC       Eye pigment precursor importer (TC 3.A.1.204) subfamily. {ECO:0000305}.
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DR   EMBL; AB005246; BAB09847.1; -; Genomic_DNA.
DR   EMBL; CP002688; AED97372.1; -; Genomic_DNA.
DR   RefSeq; NP_200882.4; NM_125467.5.
DR   AlphaFoldDB; Q9FF46; -.
DR   SMR; Q9FF46; -.
DR   BioGRID; 21439; 1.
DR   STRING; 3702.AT5G60740.1; -.
DR   TCDB; 3.A.1.204.38; the atp-binding cassette (abc) superfamily.
DR   PaxDb; Q9FF46; -.
DR   PRIDE; Q9FF46; -.
DR   ProteomicsDB; 245115; -.
DR   EnsemblPlants; AT5G60740.1; AT5G60740.1; AT5G60740.
DR   GeneID; 836195; -.
DR   Gramene; AT5G60740.1; AT5G60740.1; AT5G60740.
DR   KEGG; ath:AT5G60740; -.
DR   Araport; AT5G60740; -.
DR   TAIR; locus:2175826; AT5G60740.
DR   eggNOG; KOG0061; Eukaryota.
DR   HOGENOM; CLU_000604_57_0_1; -.
DR   InParanoid; Q9FF46; -.
DR   OMA; AFFCMIT; -.
DR   OrthoDB; 1022017at2759; -.
DR   PhylomeDB; Q9FF46; -.
DR   PRO; PR:Q9FF46; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   ExpressionAtlas; Q9FF46; baseline and differential.
DR   Genevisible; Q9FF46; AT.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IBA:GO_Central.
DR   GO; GO:0090404; C:pollen tube tip; IDA:TAIR.
DR   GO; GO:0099503; C:secretory vesicle; IDA:TAIR.
DR   GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042626; F:ATPase-coupled transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0009860; P:pollen tube growth; IMP:TAIR.
DR   GO; GO:0015846; P:polyamine transport; IMP:TAIR.
DR   GO; GO:0055085; P:transmembrane transport; IBA:GO_Central.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR043926; ABCG_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF19055; ABC2_membrane_7; 1.
DR   Pfam; PF00005; ABC_tran; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Membrane; Nucleotide-binding; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..1109
FT                   /note="ABC transporter G family member 28"
FT                   /id="PRO_0000240700"
FT   TRANSMEM        5..25
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        291..311
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        879..899
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        904..924
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        954..974
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        986..1006
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        1008..1028
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        1084..1104
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          499..741
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   DOMAIN          859..1056
FT                   /note="ABC transmembrane type-2"
FT   REGION          325..411
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        325..356
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         533..540
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ   SEQUENCE   1109 AA;  123342 MW;  B5A425393406FD82 CRC64;
     MGRRNSYFPG NFVPLFFVFI VLILQQERVI CQEDRSLDNP AANRLYNQFV FDKISNLTEV
     FEDDIKRELG FCITNVKEDY NEAFNFSTKP DFLNACGKTT KGDMMQRICT AAEVRIYFNG
     LLGGAKRATN YLKPNKNCNL SSWMSGCEPG WACRTAKDVK VDLKDDKNVP VRTQQCAPCC
     AGFFCPRGIT CMIPCPLGAY CPEANLNRTT GLCDPYHYQL PSGQPNHTCG GADIWADIGS
     SSEVFCSAGS FCPSTIDKLP CTKGHYCRTG STAELNCFKL ATCNPRSTNQ NITAYGIMLF
     AGLGFLLIIL YNCSDQVLAT RERRQAKSRE KAVQSVRDSQ SREKWKSAKD IAKKHATELQ
     QSFSRTFSRR KSMKQPDLMR GLSQAKPGSD AALPPMLGSS SDTKKGKKKE KNKLTEMLHD
     IEQNPEDPEG FNLEIGDKNI KKHAPKGKAL HTQSQMFRYA YGQIEKEKAM QEQNKNLTFS
     GVISMANDID IRKRPMIEVA FKDLSITLKG KNKHLMRCVT GKLSPGRVSA VMGPSGAGKT
     TFLTALTGKA PGCIMTGMIL VNGKVESIQS YKKIIGFVPQ DDIVHGNLTV EENLWFSARC
     RLPADLPKPE KVLVVERVIE SLGLQHVRDS LVGTVEKRGI SGGQRKRVNV GLEMVMEPSL
     LILDEPTSGL DSSSSQLLLR ALRREALEGV NICMVVHQPS YTLFRMFDDL ILLAKGGLIC
     YQGPVKKVEE YFSSLGIVVP ERVNPPDYYI DILEGILKPS TSSGVTYKQL PVRWMLHNGY
     PVPMDMLKSI EGMASSASGE NSAHGGSAHG SVVGDDGTSF AGEFWQDVKA NVEIKKDNLQ
     NNFSSSGDLS EREVPGVYQQ YRYFLGRLGK QRLREARTLA VDYLILLLAG ICLGTLAKVS
     DETFGAMGYT YTVIAVSLLC KITALRSFSL DKLHYWRESR AGMSSLAYFL AKDTVDHFNT
     IVKPLVYLSM FYFFNNPRST VTDNYVVLIC LVYCVTGIAY TLAILFEPGP AQLWSVLLPV
     VLTLIATSTN DNKIVDSISE LCYTRWALEA FVVSNAQRYK GVWLITRCGS LMENGYNIKH
     FPRCLVFLTL TGILSRCAAF FCMVTFQKK