ID   RP54_HELPJ              Reviewed;         414 AA.
AC   Q9ZLC8;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   03-AUG-2022, entry version 119.
DE   RecName: Full=RNA polymerase sigma-54 factor;
GN   Name=rpoN; OrderedLocusNames=jhp_0652;
OS   Helicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99).
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=85963;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=J99 / ATCC 700824;
RX   PubMed=9923682; DOI=10.1038/16495;
RA   Alm R.A., Ling L.-S.L., Moir D.T., King B.L., Brown E.D., Doig P.C.,
RA   Smith D.R., Noonan B., Guild B.C., deJonge B.L., Carmel G., Tummino P.J.,
RA   Caruso A., Uria-Nickelsen M., Mills D.M., Ives C., Gibson R., Merberg D.,
RA   Mills S.D., Jiang Q., Taylor D.E., Vovis G.F., Trust T.J.;
RT   "Genomic sequence comparison of two unrelated isolates of the human gastric
RT   pathogen Helicobacter pylori.";
RL   Nature 397:176-180(1999).
CC   -!- FUNCTION: Sigma factors are initiation factors that promote the
CC       attachment of RNA polymerase to specific initiation sites and are then
CC       released.
CC   -!- SIMILARITY: Belongs to the sigma-54 factor family. {ECO:0000305}.
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DR   EMBL; AE001439; AAD06228.1; -; Genomic_DNA.
DR   PIR; F71905; F71905.
DR   RefSeq; WP_000996390.1; NZ_CP011330.1.
DR   AlphaFoldDB; Q9ZLC8; -.
DR   SMR; Q9ZLC8; -.
DR   STRING; 85963.jhp_0652; -.
DR   EnsemblBacteria; AAD06228; AAD06228; jhp_0652.
DR   KEGG; hpj:jhp_0652; -.
DR   PATRIC; fig|85963.30.peg.329; -.
DR   eggNOG; COG1508; Bacteria.
DR   OMA; NPPAIEF; -.
DR   Proteomes; UP000000804; Chromosome.
DR   GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0001216; F:DNA-binding transcription activator activity; IEA:InterPro.
DR   GO; GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; IEA:InterPro.
DR   Gene3D; 1.10.10.1330; -; 1.
DR   InterPro; IPR000394; RNA_pol_sigma_54.
DR   InterPro; IPR007046; RNA_pol_sigma_54_core-bd.
DR   InterPro; IPR007634; RNA_pol_sigma_54_DNA-bd.
DR   InterPro; IPR038709; RpoN_core-bd_sf.
DR   PANTHER; PTHR32248; PTHR32248; 1.
DR   Pfam; PF00309; Sigma54_AID; 1.
DR   Pfam; PF04963; Sigma54_CBD; 1.
DR   Pfam; PF04552; Sigma54_DBD; 1.
DR   PIRSF; PIRSF000774; RpoN; 1.
DR   PRINTS; PR00045; SIGMA54FCT.
DR   TIGRFAMs; TIGR02395; rpoN_sigma; 1.
DR   PROSITE; PS00717; SIGMA54_1; 1.
DR   PROSITE; PS00718; SIGMA54_2; 1.
DR   PROSITE; PS50044; SIGMA54_3; 1.
PE   3: Inferred from homology;
KW   DNA-binding; DNA-directed RNA polymerase; Nucleotidyltransferase;
KW   Sigma factor; Transcription; Transcription regulation; Transferase.
FT   CHAIN           1..414
FT                   /note="RNA polymerase sigma-54 factor"
FT                   /id="PRO_0000205532"
FT   DNA_BIND        301..320
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000250"
FT   MOTIF           387..395
FT                   /note="RPON box"
SQ   SEQUENCE   414 AA;  48247 MW;  879845780DB89FD3 CRC64;
     MAILRANLSP KNKLNATLKG WLPILQSELE DLEEVLKQNA LDNPLIKIEN KRIKNFSDRF
     NTKKSSDHLE NCATASKSLF ETLESQIIPP LFPTETSQKI AMDIISGLNN EGYFEENIEE
     RAKVLGVESE VYEKVRKRFS YLNPAGIGAK DVKEGFLFQL DGRELDNNEL YEETRKIILN
     LEKHHEFSKD FYYEKALKIL KSFKNPPAIE FLEKEIEVIP ELFILEVDNE MIVRLNDESY
     PTISLEENRF KDSDYLKEKL KEAKDLIDAL NLRKATIYKI GLMLLEYQYD FFKGKELRPL
     KLLDLANEFN HSVSTISRAI SNKYLACERG VFPIKHFFSI ALDNSETSNA VIKDYLLELI
     KNEDKKEPLS DAKILELIEE KFHLKMVRRT ITKYRQLLNI ASSSERKRLY LMRA